STRINGSTRING
LOC101345239 LOC101345239 LOC101357840 LOC101357840 LOC101356840 LOC101356840 LOC101341952 LOC101341952 LOC101358626 LOC101358626 LOC101357085 LOC101357085 LOC101361653 LOC101361653 LOC101360368 LOC101360368 LOC101342638 LOC101342638 LOC101348142 LOC101348142 LOC101346277 LOC101346277 LOC101345850 LOC101345850 LOC101357016 LOC101357016 LOC101352434 LOC101352434 LOC101357613 LOC101357613 LOC101351573 LOC101351573 LOC101355330 LOC101355330 LOC101345018 LOC101345018 LOC101350704 LOC101350704 LOC101344705 LOC101344705 LOC101351746 LOC101351746 LOC101356454 LOC101356454 LOC101356862 LOC101356862 LOC101353227 LOC101353227 LOC101340366 LOC101340366 LOC101348250 LOC101348250 LOC101343591 LOC101343591 LOC101349018 LOC101349018 LOC101348506 LOC101348506 LOC101344372 LOC101344372 LOC101348759 LOC101348759 LOC101343332 LOC101343332 LOC101345785 LOC101345785 LOC101351408 LOC101351408 LOC101354503 LOC101354503 LOC101343945 LOC101343945 LOC101341480 LOC101341480 LOC101340818 LOC101340818 LOC101352015 LOC101352015 LOC101343253 LOC101343253 LOC101359460 LOC101359460 LOC101349290 LOC101349290 LOC101341078 LOC101341078 LOC101341582 LOC101341582 LOC101341082 LOC101341082 LOC101350143 LOC101350143 LOC101352985 LOC101352985 LOC101344230 LOC101344230 LOC101353247 LOC101353247 LOC101347686 LOC101347686 LOC101353066 LOC101353066 LOC101355199 LOC101355199 LOC101352550 LOC101352550 LOC101360334 LOC101360334 LOC101346669 LOC101346669 LOC101354943 LOC101354943 LOC101355114 LOC101355114 LOC101358244 LOC101358244 LOC101355540 LOC101355540 LOC101351514 LOC101351514 LOC101360945 LOC101360945 LOC101355625 LOC101355625 LOC101343271 LOC101343271 LOC101345222 LOC101345222 LOC101351254 LOC101351254 LOC101360343 LOC101360343 LOC101355368 LOC101355368 LOC101341671 LOC101341671 LOC101357819 LOC101357819 LOC101356743 LOC101356743 LOC101352296 LOC101352296 LOC101359745 LOC101359745 LOC101356822 LOC101356822 LOC101347525 LOC101347525 LOC101359224 LOC101359224 LOC101341352 LOC101341352 LOC101353435 LOC101353435 LOC101354868 LOC101354868 LOC101340589 LOC101340589 LOC101353082 LOC101353082 LOC101349665 LOC101349665 LOC101349243 LOC101349243 LOC101352672 LOC101352672 LOC101346092 LOC101346092 LOC101353011 LOC101353011 LOC101346019 LOC101346019 LOC101359245 LOC101359245 LOC101354392 LOC101354392 LOC101356093 LOC101356093 LOC101350438 LOC101350438 LOC101350695 LOC101350695 LOC101358487 LOC101358487 LOC101358846 LOC101358846 LOC101361121 LOC101361121 LOC101344991 LOC101344991 LOC101353424 LOC101353424 LOC101347250 LOC101347250 LOC101342555 LOC101342555 LOC101359111 LOC101359111 LOC101346368 LOC101346368 LOC101359059 LOC101359059 LOC101361837 LOC101361837 LOC101346784 LOC101346784 LOC101348995 LOC101348995 LOC101349182 LOC101349182 LOC101346209 LOC101346209 LOC101342804 LOC101342804 LOC101340959 LOC101340959 LOC101348553 LOC101348553 LOC101345959 LOC101345959 LOC101346473 LOC101346473 LOC101356953 LOC101356953 LOC101345270 LOC101345270 LOC101341715 LOC101341715 LOC101343689 LOC101343689 LOC101346475 LOC101346475 LOC101346041 LOC101346041 LOC101352786 LOC101352786 LOC101347848 LOC101347848 LOC101345455 LOC101345455 LOC101355453 LOC101355453 LOC101356476 LOC101356476 LOC101348272 LOC101348272 LOC101346534 LOC101346534 LOC101343394 LOC101343394 LOC101349967 LOC101349967 LOC101361359 LOC101361359 LOC101342008 LOC101342008 LOC101346316 LOC101346316 LOC101361961 LOC101361961 LOC101357894 LOC101357894 LOC101344242 LOC101344242 LOC101347440 LOC101347440 LOC101347126 LOC101347126 LOC101354532 LOC101354532 LOC101344808 LOC101344808 LOC101344143 LOC101344143 LOC101361375 LOC101361375 LOC101347192 LOC101347192 LOC101344889 LOC101344889 LOC101356404 LOC101356404 LOC101358526 LOC101358526 LOC101351543 LOC101351543 LOC101341433 LOC101341433 LOC101355751 LOC101355751
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101345239Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (391 aa)
LOC101357840RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
LOC101356840Transforming protein RhoA. (193 aa)
LOC101341952Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (355 aa)
LOC101358626Voltage-dependent calcium channel subunit alpha-2/delta-3. (1091 aa)
LOC101357085Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2179 aa)
LOC101361653Transcription factor AP-1; Belongs to the bZIP family. (329 aa)
LOC101360368Non-specific serine/threonine protein kinase. (552 aa)
LOC101342638cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
LOC101348142Neuroendocrine secretory protein 55. (248 aa)
LOC101346277Myosin regulatory light polypeptide 9. (172 aa)
LOC101345850Myosin light chain kinase 2, skeletal/cardiac muscle. (606 aa)
LOC101357016Proto-oncogene c-Fos. (380 aa)
LOC101352434Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1074 aa)
LOC101357613Guanine nucleotide-binding protein G(O) subunit alpha isoform X1. (354 aa)
LOC101351573Guanylate cyclase. (1047 aa)
LOC101355330Calcineurin subunit B type 2. (170 aa)
LOC101345018Prostaglandin G/H synthase 2. (604 aa)
LOC101350704Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
LOC101344705Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC101351746Eukaryotic elongation factor 2 kinase. (725 aa)
LOC101356454Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC101356862Voltage-dependent calcium channel gamma-3 subunit. (315 aa)
LOC101353227Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
LOC101340366Inward rectifier potassium channel 4. (444 aa)
LOC101348250Protein kinase C alpha type isoform X2. (549 aa)
LOC101343591Inward rectifier potassium channel 2. (427 aa)
LOC101349018Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
LOC101348506Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
LOC101344372Actin, cytoplasmic 2. (375 aa)
LOC101348759Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
LOC101343332Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC101345785Dual specificity mitogen-activated protein kinase kinase 5 isoform X1; Belongs to the protein kinase superfamily. (448 aa)
LOC101351408Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (519 aa)
LOC101354503G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
LOC101343945Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
LOC1013414805'-AMP-activated protein kinase subunit gamma-3. (500 aa)
LOC101340818Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1975 aa)
LOC101352015ETS domain-containing protein Elk-1. (432 aa)
LOC101343253Calcium/calmodulin-dependent protein kinase type IV isoform X3; Belongs to the protein kinase superfamily. (472 aa)
LOC101359460Natriuretic peptides A. (153 aa)
LOC101349290Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
LOC101341078Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC101341582Elongation factor 2. (858 aa)
LOC101341082G protein-activated inward rectifier potassium channel 4. (419 aa)
LOC101350143Calcium/calmodulin-dependent protein kinase type 1D; Belongs to the protein kinase superfamily. (384 aa)
LOC101352985Myosin light polypeptide 6. (151 aa)
LOC101344230GTPase NRas isoform X1. (189 aa)
LOC101353247Myosin light chain 6B. (215 aa)
LOC101347686Ryanodine receptor 3. (4875 aa)
LOC101353066Phospholipase A2. (818 aa)
LOC101355199Phospholipase A2. (850 aa)
LOC101352550Phospholipase A2. (784 aa)
LOC101360334Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (977 aa)
LOC101346669Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (799 aa)
LOC101354943Phospholipase A2. (863 aa)
LOC101355114Voltage-dependent calcium channel subunit alpha-2/delta-4. (1120 aa)
LOC101358244ATP-sensitive inward rectifier potassium channel 14. (421 aa)
LOC101355540Protein phosphatase 1 regulatory subunit. (715 aa)
LOC101351514Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
LOC101360945Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2109 aa)
LOC101355625Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (261 aa)
LOC101343271Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC101345222Voltage-dependent calcium channel subunit alpha-2/delta-1. (1091 aa)
LOC101351254Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
LOC101360343Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (730 aa)
LOC101355368Voltage-dependent calcium channel gamma-8 subunit. (550 aa)
LOC101341671Regulator of G-protein signaling 2. (213 aa)
LOC101357819Guanylate cyclase soluble subunit alpha-3 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
LOC101356743Oxytocin-neurophysin 1; Belongs to the vasopressin/oxytocin family. (125 aa)
LOC1013522961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC101359745G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
LOC101356822Receptor protein-tyrosine kinase. (1156 aa)
LOC101347525GTPase KRas isoform X3. (227 aa)
LOC101359224Calcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (486 aa)
LOC101341352Protein phosphatase 1 regulatory subunit. (1030 aa)
LOC101353435Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1; Belongs to the protein kinase superfamily. (499 aa)
LOC101354868Adenylate cyclase type 1. (903 aa)
LOC101340589Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
LOC101353082Calcium/calmodulin-dependent protein kinase type II subunit beta. (655 aa)
LOC101349665Voltage-dependent L-type calcium channel subunit beta-3 isoform X1. (484 aa)
LOC101349243Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC1013526725'-AMP-activated protein kinase subunit gamma-1 isoform X1. (331 aa)
LOC101346092Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
LOC101353011Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (389 aa)
LOC101346019Guanylate cyclase. (1056 aa)
LOC101359245G protein-activated inward rectifier potassium channel 2. (423 aa)
LOC101354392Inositol 1,4,5-trisphosphate receptor type 3. (2670 aa)
LOC101356093G protein-activated inward rectifier potassium channel 3. (393 aa)
LOC101350438Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
LOC101350695Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (900 aa)
LOC101358487Calmodulin; Belongs to the calmodulin family. (113 aa)
LOC101358846LOW QUALITY PROTEIN: calmodulin-like protein 3; Belongs to the calmodulin family. (148 aa)
LOC101361121LOW QUALITY PROTEIN: calmodulin-like protein 6. (188 aa)
LOC101344991Voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1. (1081 aa)
LOC101353424Serine/threonine-protein phosphatase. (525 aa)
LOC101347250Guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (602 aa)
LOC101342555Tyrosine-protein kinase. (542 aa)
LOC101359111Calmodulin-like. (149 aa)
LOC101346368ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1. (294 aa)
LOC101359059Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (933 aa)
LOC101361837Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (922 aa)
LOC101346784Non-specific serine/threonine protein kinase. (565 aa)
LOC101348995cAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
LOC1013491825'-AMP-activated protein kinase subunit gamma-2 isoform X1. (574 aa)
LOC101346209Ryanodine receptor 2. (5041 aa)
LOC101342804GTPase HRas isoform X1. (189 aa)
LOC101340959Myosin light chain kinase, smooth muscle isoform X1. (1961 aa)
LOC101348553Calcium/calmodulin-dependent protein kinase type 1; Belongs to the protein kinase superfamily. (370 aa)
LOC101345959Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1405 aa)
LOC101346473Calmodulin-like protein 4. (153 aa)
LOC101356953Nitric oxide synthase; Produces nitric oxide (NO). (1214 aa)
LOC101345270Phospholipase A2. (757 aa)
LOC101341715Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
LOC101343689Phosphoinositide 3-kinase regulatory subunit 5. (875 aa)
LOC101346475Myocyte-specific enhancer factor 2C isoform X1. (483 aa)
LOC101346041Adenylate cyclase type 5. (1265 aa)
LOC101352786Phosphoinositide 3-kinase regulatory subunit 6. (422 aa)
LOC101347848LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase kinase 2. (548 aa)
LOC101345455Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
LOC101355453ATP-sensitive inward rectifier potassium channel 12. (435 aa)
LOC1013564765'-AMP-activated protein kinase subunit beta-2 isoform X1. (282 aa)
LOC101348272Voltage-dependent L-type calcium channel subunit beta-2. (595 aa)
LOC101346534Inositol 1,4,5-trisphosphate receptor type 1. (2715 aa)
LOC101343394Calcineurin subunit B type 1 isoform X1. (170 aa)
LOC101349967Phosphoinositide phospholipase C. (909 aa)
LOC1013613595'-AMP-activated protein kinase subunit beta-1 isoform X1. (271 aa)
LOC101342008Cyclin-dependent kinase inhibitor 1 isoform X1. (189 aa)
LOC101346316Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (319 aa)
LOC101361961Calcium/calmodulin-dependent protein kinase type II subunit gamma. (821 aa)
LOC101357894Serine/threonine-protein phosphatase. (511 aa)
LOC1013442421-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1226 aa)
LOC101347440Serine/threonine-protein phosphatase. (418 aa)
LOC101347126Calmodulin-2 isoform X1; Belongs to the calmodulin family. (153 aa)
LOC101354532Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1102 aa)
LOC101344808Transient receptor potential cation channel subfamily M member 2 isoform X1. (1477 aa)
LOC101344143Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (614 aa)
LOC1013613751-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1166 aa)
LOC101347192Guanine nucleotide-binding protein G(Q) subunit alpha isoform X3. (381 aa)
LOC101344889Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (348 aa)
LOC101356404Inositol 1,4,5-trisphosphate receptor type 2. (2441 aa)
LOC101358526Mitogen-activated protein kinase 1. (263 aa)
LOC101351543Ryanodine receptor 1. (4842 aa)
LOC101341433Calcipressin-1 isoform X1. (207 aa)
LOC101355751Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (930 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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