STRINGSTRING
LOC101353522 LOC101353522 LOC101357085 LOC101357085 LOC101342638 LOC101342638 LOC101349247 LOC101349247 LOC101348142 LOC101348142 LOC101350704 LOC101350704 LOC101344705 LOC101344705 LOC101356454 LOC101356454 LOC101345870 LOC101345870 LOC101345357 LOC101345357 LOC101348250 LOC101348250 LOC101357207 LOC101357207 LOC101343945 LOC101343945 LOC101355181 LOC101355181 LOC101352110 LOC101352110 LOC101340818 LOC101340818 LOC101343253 LOC101343253 LOC101359460 LOC101359460 LOC101349290 LOC101349290 LOC101350203 LOC101350203 LOC101355436 LOC101355436 LOC101345798 LOC101345798 LOC101345890 LOC101345890 LOC101355964 LOC101355964 LOC101348360 LOC101348360 LOC101341082 LOC101341082 LOC101350143 LOC101350143 LOC101346145 LOC101346145 LOC101358325 LOC101358325 LOC101361788 LOC101361788 LOC101348695 LOC101348695 LOC101360334 LOC101360334 LOC101361533 LOC101361533 LOC101360945 LOC101360945 LOC101351254 LOC101351254 LOC101352296 LOC101352296 LOC101349137 LOC101349137 LOC101340320 LOC101340320 LOC101347779 LOC101347779 LOC101358687 LOC101358687 LOC101359224 LOC101359224 LOC101343204 LOC101343204 LOC101353435 LOC101353435 LOC101354868 LOC101354868 LOC101353082 LOC101353082 LOC101350672 LOC101350672 LOC101349243 LOC101349243 LOC101361911 LOC101361911 LOC101344076 LOC101344076 LOC101346019 LOC101346019 LOC101345071 LOC101345071 LOC101344337 LOC101344337 LOC101354392 LOC101354392 LOC101345427 LOC101345427 LOC101350438 LOC101350438 LOC101359950 LOC101359950 LOC101355408 LOC101355408 LOC101359524 LOC101359524 LOC101358487 LOC101358487 LOC101358846 LOC101358846 LOC101359884 LOC101359884 LOC101361121 LOC101361121 LOC101359111 LOC101359111 LOC101359783 LOC101359783 LOC101361837 LOC101361837 LOC101348995 LOC101348995 LOC101361490 LOC101361490 LOC101351576 LOC101351576 LOC101348553 LOC101348553 LOC101346473 LOC101346473 LOC101341715 LOC101341715 LOC101352607 LOC101352607 LOC101344111 LOC101344111 LOC101346041 LOC101346041 LOC101342003 LOC101342003 LOC101341230 LOC101341230 LOC101356881 LOC101356881 LOC101356210 LOC101356210 LOC101343098 LOC101343098 LOC101351856 LOC101351856 LOC101346534 LOC101346534 LOC101349967 LOC101349967 LOC101361961 LOC101361961 LOC101344242 LOC101344242 LOC101347126 LOC101347126 LOC101341622 LOC101341622 LOC101343540 LOC101343540 LOC101352129 LOC101352129 LOC101361375 LOC101361375 LOC101347192 LOC101347192 LOC101356404 LOC101356404 LOC101345311 LOC101345311 LOC101346441 LOC101346441 LOC101361564 LOC101361564
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101353522Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
LOC101357085Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2179 aa)
LOC101342638cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
LOC101349247Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
LOC101348142Neuroendocrine secretory protein 55. (248 aa)
LOC101350704Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
LOC101344705Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC101356454Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC101345870Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2178 aa)
LOC101345357Cyclic AMP-dependent transcription factor ATF-4. (352 aa)
LOC101348250Protein kinase C alpha type isoform X2. (549 aa)
LOC101357207Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (521 aa)
LOC101343945Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
LOC101355181Nuclear receptor subfamily 4 group A member 2 isoform X1. (609 aa)
LOC101352110Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
LOC101340818Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1975 aa)
LOC101343253Calcium/calmodulin-dependent protein kinase type IV isoform X3; Belongs to the protein kinase superfamily. (472 aa)
LOC101359460Natriuretic peptides A. (153 aa)
LOC101349290Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
LOC101350203Pro-opiomelanocortin. (270 aa)
LOC101355436Potassium channel subfamily K member. (400 aa)
LOC101345798Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
LOC101345890Guanine nucleotide-binding protein subunit alpha-11. (354 aa)
LOC101355964Cyclic AMP-responsive element-binding protein 3-like protein 3. (483 aa)
LOC101348360Calcium release-activated calcium channel protein 1. (218 aa)
LOC101341082G protein-activated inward rectifier potassium channel 4. (419 aa)
LOC101350143Calcium/calmodulin-dependent protein kinase type 1D; Belongs to the protein kinase superfamily. (384 aa)
LOC101346145Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC1013583253 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2; Belongs to the 3-beta-HSD family. (373 aa)
LOC101361788Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
LOC101348695Sn1-specific diacylglycerol lipase beta isoform X1. (670 aa)
LOC101360334Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (977 aa)
LOC101361533Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (879 aa)
LOC101360945Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2109 aa)
LOC101351254Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
LOC1013522961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC101349137Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
LOC101340320Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
LOC101347779Sn1-specific diacylglycerol lipase alpha. (1040 aa)
LOC101358687Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
LOC101359224Calcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (486 aa)
LOC101343204Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
LOC101353435Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1; Belongs to the protein kinase superfamily. (499 aa)
LOC101354868Adenylate cyclase type 1. (903 aa)
LOC101353082Calcium/calmodulin-dependent protein kinase type II subunit beta. (655 aa)
LOC101350672Potassium channel subfamily K member. (372 aa)
LOC101349243Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC101361911Cyclic AMP-dependent transcription factor ATF-1 isoform X1. (279 aa)
LOC101344076Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
LOC101346019Guanylate cyclase. (1056 aa)
LOC101345071Sodium/potassium-transporting ATPase subunit alpha. (983 aa)
LOC101344337Cyclic AMP-responsive element-binding protein 3-like protein 4. (395 aa)
LOC101354392Inositol 1,4,5-trisphosphate receptor type 3. (2670 aa)
LOC101345427Adrenocorticotropic hormone receptor. (300 aa)
LOC101350438Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
LOC101359950Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1221 aa)
LOC101355408Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
LOC101359524Steroid 21-hydroxylase; Belongs to the cytochrome P450 family. (494 aa)
LOC101358487Calmodulin; Belongs to the calmodulin family. (113 aa)
LOC101358846LOW QUALITY PROTEIN: calmodulin-like protein 3; Belongs to the calmodulin family. (148 aa)
LOC101359884Cyclic AMP-dependent transcription factor ATF-2. (455 aa)
LOC101361121LOW QUALITY PROTEIN: calmodulin-like protein 6. (188 aa)
LOC101359111Calmodulin-like. (149 aa)
LOC101359783Cyclic AMP-dependent transcription factor ATF-6 beta. (711 aa)
LOC101361837Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (922 aa)
LOC101348995cAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
LOC101361490Sodium/potassium-transporting ATPase subunit alpha. (824 aa)
LOC101351576Angiotensinogen; Belongs to the serpin family. (491 aa)
LOC101348553Calcium/calmodulin-dependent protein kinase type 1; Belongs to the protein kinase superfamily. (370 aa)
LOC101346473Calmodulin-like protein 4. (153 aa)
LOC101341715Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
LOC101352607Cyclic AMP-responsive element-binding protein 3. (377 aa)
LOC101344111Voltage-dependent T-type calcium channel subunit alpha-1H. (2355 aa)
LOC101346041Adenylate cyclase type 5. (1265 aa)
LOC101342003Low-density lipoprotein receptor. (866 aa)
LOC101341230Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (917 aa)
LOC101356881Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
LOC101356210Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
LOC101343098Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (355 aa)
LOC101351856Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2379 aa)
LOC101346534Inositol 1,4,5-trisphosphate receptor type 1. (2715 aa)
LOC101349967Phosphoinositide phospholipase C. (909 aa)
LOC101361961Calcium/calmodulin-dependent protein kinase type II subunit gamma. (821 aa)
LOC1013442421-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1226 aa)
LOC101347126Calmodulin-2 isoform X1; Belongs to the calmodulin family. (153 aa)
LOC101341622Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (890 aa)
LOC101343540Scavenger receptor class B member 1; Belongs to the CD36 family. (507 aa)
LOC101352129Phosphodiesterase. (948 aa)
LOC1013613751-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1166 aa)
LOC101347192Guanine nucleotide-binding protein G(Q) subunit alpha isoform X3. (381 aa)
LOC101356404Inositol 1,4,5-trisphosphate receptor type 2. (2441 aa)
LOC101345311Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
LOC101346441Nuclear receptor subfamily 4 group A member 1 isoform X1. (649 aa)
LOC101361564Hormone-sensitive lipase. (771 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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