STRINGSTRING
LOC101357840 LOC101357840 LOC101341952 LOC101341952 LOC101345326 LOC101345326 LOC101361653 LOC101361653 LOC101342638 LOC101342638 LOC101351720 LOC101351720 LOC101359592 LOC101359592 LOC101348142 LOC101348142 LOC101347888 LOC101347888 LOC101357016 LOC101357016 LOC101347392 LOC101347392 LOC101357613 LOC101357613 LOC101351035 LOC101351035 LOC101358817 LOC101358817 LOC101359953 LOC101359953 LOC101357541 LOC101357541 LOC101350704 LOC101350704 LOC101344705 LOC101344705 LOC101351136 LOC101351136 LOC101359012 LOC101359012 LOC101345357 LOC101345357 LOC101348250 LOC101348250 LOC101347746 LOC101347746 LOC101343332 LOC101343332 LOC101355353 LOC101355353 LOC101360493 LOC101360493 LOC101354258 LOC101354258 LOC101349290 LOC101349290 LOC101345798 LOC101345798 LOC101354262 LOC101354262 LOC101359726 LOC101359726 LOC101346746 LOC101346746 LOC101341078 LOC101341078 LOC101355964 LOC101355964 LOC101361614 LOC101361614 LOC101342004 LOC101342004 LOC101349964 LOC101349964 LOC101361872 LOC101361872 LOC101344230 LOC101344230 LOC101352466 LOC101352466 LOC101351866 LOC101351866 LOC101360334 LOC101360334 LOC101360162 LOC101360162 LOC101343271 LOC101343271 LOC101348280 LOC101348280 LOC101345564 LOC101345564 LOC101349561 LOC101349561 LOC101352296 LOC101352296 LOC101349137 LOC101349137 LOC101342107 LOC101342107 LOC101356822 LOC101356822 LOC101360084 LOC101360084 LOC101347525 LOC101347525 LOC101352912 LOC101352912 LOC101346849 LOC101346849 LOC101343804 LOC101343804 LOC101350086 LOC101350086 LOC101355897 LOC101355897 LOC101340756 LOC101340756 LOC101354868 LOC101354868 LOC101351888 LOC101351888 LOC101342034 LOC101342034 LOC101355900 LOC101355900 LOC101341516 LOC101341516 LOC101340589 LOC101340589 LOC101341020 LOC101341020 LOC101341777 LOC101341777 LOC101344331 LOC101344331 LOC101355136 LOC101355136 LOC101345319 LOC101345319 LOC101349243 LOC101349243 LOC101344076 LOC101344076 LOC101346092 LOC101346092 LOC101358105 LOC101358105 LOC101344337 LOC101344337 LOC101353198 LOC101353198 LOC101360380 LOC101360380 LOC101351734 LOC101351734 LOC101350438 LOC101350438 LOC101348656 LOC101348656 LOC101359884 LOC101359884 LOC101356099 LOC101356099 LOC101355426 LOC101355426 LOC101341327 LOC101341327 LOC101349706 LOC101349706 LOC101356579 LOC101356579 LOC101342555 LOC101342555 LOC101345305 LOC101345305 LOC101359783 LOC101359783 LOC101343546 LOC101343546 LOC101350595 LOC101350595 LOC101361837 LOC101361837 LOC111819060 LOC111819060 LOC101348995 LOC101348995 LOC101352593 LOC101352593 LOC101355579 LOC101355579 LOC101342804 LOC101342804 LOC111819711 LOC111819711 LOC101356953 LOC101356953 LOC101341715 LOC101341715 LOC101352607 LOC101352607 LOC101350197 LOC101350197 LOC101351188 LOC101351188 LOC101341907 LOC101341907 LOC101346041 LOC101346041 LOC101356881 LOC101356881 LOC101341920 LOC101341920 LOC101360148 LOC101360148 LOC101349700 LOC101349700 LOC101347845 LOC101347845 LOC101347350 LOC101347350 LOC111821467 LOC111821467 LOC101358678 LOC101358678 LOC101349967 LOC101349967 LOC101344242 LOC101344242 LOC101354945 LOC101354945 LOC101352051 LOC101352051 LOC101359658 LOC101359658 LOC101350742 LOC101350742 LOC101357176 LOC101357176 LOC101358346 LOC101358346 LOC101361375 LOC101361375 LOC101361706 LOC101361706 LOC101358526 LOC101358526 LOC101359491 LOC101359491 LOC101342543 LOC101342543
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101357840RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
LOC101341952Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (355 aa)
LOC101345326Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC101361653Transcription factor AP-1; Belongs to the bZIP family. (329 aa)
LOC101342638cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
LOC101351720Insulin-like peptide INSL5. (135 aa)
LOC101359592Son of sevenless homolog 1 isoform X1. (1333 aa)
LOC101348142Neuroendocrine secretory protein 55. (248 aa)
LOC101347888Matrix metalloproteinase-9. (724 aa)
LOC101357016Proto-oncogene c-Fos. (380 aa)
LOC101347392Son of sevenless homolog 2 isoform X1. (1328 aa)
LOC101357613Guanine nucleotide-binding protein G(O) subunit alpha isoform X1. (354 aa)
LOC101351035Phosphatidylinositol 3-kinase regulatory subunit gamma. (462 aa)
LOC10135881772 kDa type IV collagenase. (659 aa)
LOC101359953Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
LOC101357541Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC101350704Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
LOC101344705Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC101351136Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
LOC101359012Growth factor receptor-bound protein 2. (176 aa)
LOC101345357Cyclic AMP-dependent transcription factor ATF-4. (352 aa)
LOC101348250Protein kinase C alpha type isoform X2. (549 aa)
LOC101347746Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC101343332Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC101355353NF-kappa-B inhibitor alpha. (314 aa)
LOC101360493Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC101354258TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LOC101349290Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
LOC101345798Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
LOC101354262Collagen alpha-1(I) chain. (1460 aa)
LOC101359726SHC-transforming protein 2. (428 aa)
LOC101346746Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
LOC101341078Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC101355964Cyclic AMP-responsive element-binding protein 3-like protein 3. (483 aa)
LOC101361614Mitogen-activated protein kinase. (283 aa)
LOC101342004Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa)
LOC101349964Collagen alpha-5(IV) chain isoform X2. (1691 aa)
LOC101361872Mitogen-activated protein kinase. (366 aa)
LOC101344230GTPase NRas isoform X1. (189 aa)
LOC101352466Mitogen-activated protein kinase. (595 aa)
LOC101351866Nuclear factor NF-kappa-B p105 subunit isoform X1. (997 aa)
LOC101360334Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (977 aa)
LOC101360162Relaxin receptor 1 isoform X1. (807 aa)
LOC101343271Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC101348280Guanine nucleotide-binding protein subunit beta-4. (340 aa)
LOC101345564Collagen alpha-2(IV) chain. (1710 aa)
LOC101349561Endothelin-1. (207 aa)
LOC1013522961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC101349137Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
LOC101342107Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC101356822Receptor protein-tyrosine kinase. (1156 aa)
LOC101360084SHC-transforming protein 3. (616 aa)
LOC101347525GTPase KRas isoform X3. (227 aa)
LOC101352912Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
LOC101346849Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101343804Phosphatidylinositol 3-kinase regulatory subunit beta. (729 aa)
LOC101350086Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
LOC101355897Collagen alpha-3(IV) chain. (1670 aa)
LOC101340756Collagenase 3. (471 aa)
LOC101354868Adenylate cyclase type 1. (903 aa)
LOC101351888LOW QUALITY PROTEIN: relaxin receptor 2. (753 aa)
LOC101342034Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
LOC101355900SHC-transforming protein 4. (629 aa)
LOC101341516Interstitial collagenase. (471 aa)
LOC101340589Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
LOC101341020Collagen alpha-2(I) chain isoform X2. (1367 aa)
LOC101341777Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC101344331Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
LOC101355136Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
LOC101345319Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
LOC101349243Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC101344076Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
LOC101346092Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
LOC101358105SHC-transforming protein 1 isoform X1. (584 aa)
LOC101344337Cyclic AMP-responsive element-binding protein 3-like protein 4. (395 aa)
LOC101353198Relaxin-3 receptor 2. (383 aa)
LOC101360380Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
LOC101351734Mitogen-activated protein kinase. (464 aa)
LOC101350438Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
LOC101348656Mothers against decapentaplegic homolog. (467 aa)
LOC101359884Cyclic AMP-dependent transcription factor ATF-2. (455 aa)
LOC101356099Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC101355426Prorelaxin-like. (153 aa)
LOC101341327Guanine nucleotide-binding protein subunit beta-5. (353 aa)
LOC101349706Collagen alpha-6(IV) chain. (1713 aa)
LOC101356579Nitric oxide synthase; Produces nitric oxide (NO). (1161 aa)
LOC101342555Tyrosine-protein kinase. (542 aa)
LOC101345305Collagen alpha-1(IV) chain. (1643 aa)
LOC101359783Cyclic AMP-dependent transcription factor ATF-6 beta. (711 aa)
LOC101343546Mitogen-activated protein kinase. (427 aa)
LOC101350595Relaxin-3 receptor 1. (444 aa)
LOC101361837Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (922 aa)
LOC111819060Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC101348995cAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
LOC101352593Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (119 aa)
LOC101355579Endothelin receptor type B isoform X1; Belongs to the G-protein coupled receptor 1 family. (499 aa)
LOC101342804GTPase HRas isoform X1. (189 aa)
LOC111819711Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC101356953Nitric oxide synthase; Produces nitric oxide (NO). (1214 aa)
LOC101341715Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
LOC101352607Cyclic AMP-responsive element-binding protein 3. (377 aa)
LOC101350197Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (393 aa)
LOC101351188Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC101341907Beta-arrestin-2 isoform X1. (452 aa)
LOC101346041Adenylate cyclase type 5. (1265 aa)
LOC101356881Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
LOC101341920Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (637 aa)
LOC101360148Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
LOC101349700Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (390 aa)
LOC101347845Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 isoform X1. (112 aa)
LOC101347350Mitogen-activated protein kinase. (321 aa)
LOC111821467Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC101358678Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1082 aa)
LOC101349967Phosphoinositide phospholipase C. (909 aa)
LOC1013442421-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1226 aa)
LOC101354945Beta-arrestin-1. (395 aa)
LOC101352051Insulin-like 3. (97 aa)
LOC101359658Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
LOC101350742Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
LOC101357176Actin, aortic smooth muscle. (377 aa)
LOC101358346Collagen alpha-4(IV) chain. (1708 aa)
LOC1013613751-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1166 aa)
LOC101361706Transcription factor p65. (538 aa)
LOC101358526Mitogen-activated protein kinase 1. (263 aa)
LOC101359491Collagen alpha-1(III) chain. (1160 aa)
LOC101342543Transforming growth factor beta; Belongs to the TGF-beta family. (392 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.