STRINGSTRING
LOC101357840 LOC101357840 LOC101357085 LOC101357085 LOC101358977 LOC101358977 LOC101351029 LOC101351029 LOC101351035 LOC101351035 LOC101356454 LOC101356454 LOC101345870 LOC101345870 LOC101348250 LOC101348250 LOC101347746 LOC101347746 LOC101343332 LOC101343332 LOC101361427 LOC101361427 LOC101354503 LOC101354503 LOC101343945 LOC101343945 LOC101340818 LOC101340818 LOC101360667 LOC101360667 LOC101360493 LOC101360493 LOC101352023 LOC101352023 LOC101341078 LOC101341078 LOC101345890 LOC101345890 LOC101341082 LOC101341082 LOC101355447 LOC101355447 LOC101344230 LOC101344230 LOC101346236 LOC101346236 LOC101360945 LOC101360945 LOC101351254 LOC101351254 LOC101354944 LOC101354944 LOC101352729 LOC101352729 LOC101352296 LOC101352296 LOC101347525 LOC101347525 LOC101344491 LOC101344491 LOC101346849 LOC101346849 LOC101343804 LOC101343804 LOC101341013 LOC101341013 LOC101355130 LOC101355130 LOC101340589 LOC101340589 LOC101350923 LOC101350923 LOC101359326 LOC101359326 LOC101345506 LOC101345506 LOC101351974 LOC101351974 LOC101359245 LOC101359245 LOC101354392 LOC101354392 LOC101356093 LOC101356093 LOC101356099 LOC101356099 LOC101349961 LOC101349961 LOC101343228 LOC101343228 LOC101342560 LOC101342560 LOC101360475 LOC101360475 LOC101342804 LOC101342804 LOC101350197 LOC101350197 LOC101341907 LOC101341907 LOC101344111 LOC101344111 LOC101351856 LOC101351856 LOC101358678 LOC101358678 LOC101346534 LOC101346534 LOC101349967 LOC101349967 LOC101344242 LOC101344242 LOC101354945 LOC101354945 LOC101359658 LOC101359658 LOC101361375 LOC101361375 LOC101347192 LOC101347192 LOC101356404 LOC101356404 LOC101358526 LOC101358526 LOC101350753 LOC101350753
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101357840RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
LOC101357085Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2179 aa)
LOC101358977ATP-sensitive inward rectifier potassium channel 11 isoform X1. (390 aa)
LOC101351029Estrogen receptor beta. (547 aa)
LOC101351035Phosphatidylinositol 3-kinase regulatory subunit gamma. (462 aa)
LOC101356454Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC101345870Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2178 aa)
LOC101348250Protein kinase C alpha type isoform X2. (549 aa)
LOC101347746Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC101343332Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC101361427Metastasis-suppressor KiSS-1. (136 aa)
LOC101354503G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
LOC101343945Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
LOC101340818Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1975 aa)
LOC101360667Small conductance calcium-activated potassium channel protein 2 isoform X1. (842 aa)
LOC101360493Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC101352023Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2. (766 aa)
LOC101341078Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC101345890Guanine nucleotide-binding protein subunit alpha-11. (354 aa)
LOC101341082G protein-activated inward rectifier potassium channel 4. (419 aa)
LOC101355447Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
LOC101344230GTPase NRas isoform X1. (189 aa)
LOC101346236Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (883 aa)
LOC101360945Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2109 aa)
LOC101351254Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
LOC101354944LOW QUALITY PROTEIN: lutropin subunit beta. (181 aa)
LOC101352729Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (96 aa)
LOC1013522961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC101347525GTPase KRas isoform X3. (227 aa)
LOC101344491Small conductance calcium-activated potassium channel protein 1. (544 aa)
LOC101346849Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101343804Phosphatidylinositol 3-kinase regulatory subunit beta. (729 aa)
LOC101341013Short transient receptor potential channel 1 isoform X2; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
LOC101355130G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
LOC101340589Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
LOC101350923Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3. (780 aa)
LOC101359326Small conductance calcium-activated potassium channel protein 3 isoform X1. (733 aa)
LOC101345506Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
LOC101351974Intermediate conductance calcium-activated potassium channel protein 4. (432 aa)
LOC101359245G protein-activated inward rectifier potassium channel 2. (423 aa)
LOC101354392Inositol 1,4,5-trisphosphate receptor type 3. (2670 aa)
LOC101356093G protein-activated inward rectifier potassium channel 3. (393 aa)
LOC101356099Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC101349961LOW QUALITY PROTEIN: kiSS-1 receptor. (352 aa)
LOC101343228Osteopontin. (304 aa)
LOC101342560Short transient receptor potential channel 4 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
LOC101360475Gamma-aminobutyric acid type B receptor subunit 2. (759 aa)
LOC101342804GTPase HRas isoform X1. (189 aa)
LOC101350197Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (393 aa)
LOC101341907Beta-arrestin-2 isoform X1. (452 aa)
LOC101344111Voltage-dependent T-type calcium channel subunit alpha-1H. (2355 aa)
LOC101351856Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2379 aa)
LOC101358678Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1082 aa)
LOC101346534Inositol 1,4,5-trisphosphate receptor type 1. (2715 aa)
LOC101349967Phosphoinositide phospholipase C. (909 aa)
LOC1013442421-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1226 aa)
LOC101354945Beta-arrestin-1. (395 aa)
LOC101359658Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
LOC1013613751-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1166 aa)
LOC101347192Guanine nucleotide-binding protein G(Q) subunit alpha isoform X3. (381 aa)
LOC101356404Inositol 1,4,5-trisphosphate receptor type 2. (2441 aa)
LOC101358526Mitogen-activated protein kinase 1. (263 aa)
LOC101350753Gamma-aminobutyric acid type B receptor subunit 1. (862 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.