STRINGSTRING
LOC101341781 LOC101341781 LOC101351897 LOC101351897 LOC101341952 LOC101341952 LOC101357085 LOC101357085 LOC101342638 LOC101342638 LOC101352074 LOC101352074 LOC101354636 LOC101354636 LOC101348142 LOC101348142 LOC101342296 LOC101342296 LOC101357348 LOC101357348 LOC101358375 LOC101358375 LOC101348322 LOC101348322 LOC101361662 LOC101361662 LOC101341387 LOC101341387 LOC101344702 LOC101344702 LOC101350704 LOC101350704 LOC101344705 LOC101344705 LOC101345867 LOC101345867 LOC101351137 LOC101351137 LOC101349186 LOC101349186 LOC101345870 LOC101345870 LOC101343587 LOC101343587 LOC101345357 LOC101345357 LOC101347495 LOC101347495 LOC101342156 LOC101342156 LOC101340626 LOC101340626 LOC101347661 LOC101347661 LOC101343332 LOC101343332 LOC101357207 LOC101357207 LOC101341899 LOC101341899 LOC101343945 LOC101343945 LOC101354922 LOC101354922 LOC101359885 LOC101359885 LOC101349879 LOC101349879 LOC101347671 LOC101347671 LOC101360142 LOC101360142 LOC101341737 LOC101341737 LOC101350297 LOC101350297 LOC101355952 LOC101355952 LOC101340818 LOC101340818 LOC101349290 LOC101349290 LOC101350203 LOC101350203 LOC101355436 LOC101355436 LOC101345798 LOC101345798 LOC101358150 LOC101358150 LOC101347003 LOC101347003 LOC101341078 LOC101341078 LOC101345890 LOC101345890 LOC101355964 LOC101355964 LOC101346660 LOC101346660 LOC101348360 LOC101348360 LOC101346145 LOC101346145 LOC101358325 LOC101358325 LOC101348949 LOC101348949 LOC101360249 LOC101360249 LOC101360334 LOC101360334 LOC101353504 LOC101353504 LOC101351340 LOC101351340 LOC101359902 LOC101359902 LOC101342423 LOC101342423 LOC101360945 LOC101360945 LOC101343271 LOC101343271 LOC101362049 LOC101362049 LOC101340313 LOC101340313 LOC101357820 LOC101357820 LOC101352296 LOC101352296 LOC101349137 LOC101349137 LOC101359651 LOC101359651 LOC101340320 LOC101340320 LOC101359745 LOC101359745 LOC101343025 LOC101343025 LOC101356822 LOC101356822 LOC101345396 LOC101345396 LOC101360002 LOC101360002 LOC101359224 LOC101359224 LOC101346679 LOC101346679 LOC101359840 LOC101359840 LOC101353435 LOC101353435 LOC101354868 LOC101354868 LOC101359317 LOC101359317 LOC101360614 LOC101360614 LOC101340589 LOC101340589 LOC101353082 LOC101353082 LOC101359144 LOC101359144 LOC101360273 LOC101360273 LOC101349413 LOC101349413 LOC101361647 LOC101361647 LOC101352160 LOC101352160 LOC101349243 LOC101349243 LOC101354125 LOC101354125 LOC101351717 LOC101351717 LOC101341696 LOC101341696 LOC101344076 LOC101344076 LOC101343291 LOC101343291 LOC101346092 LOC101346092 LOC101353099 LOC101353099 LOC101344337 LOC101344337 LOC101344186 LOC101344186 LOC101354392 LOC101354392 LOC101348994 LOC101348994 LOC101345427 LOC101345427 LOC101350438 LOC101350438 LOC101359524 LOC101359524 LOC101359884 LOC101359884 LOC101354427 LOC101354427 LOC101353421 LOC101353421 LOC101348129 LOC101348129 LOC101346513 LOC101346513 LOC101359783 LOC101359783 LOC101358885 LOC101358885 LOC101356576 LOC101356576 LOC101361837 LOC101361837 LOC101348995 LOC101348995 LOC101351576 LOC101351576 LOC101340519 LOC101340519 LOC101349790 LOC101349790 LOC101359618 LOC101359618 LOC101350636 LOC101350636 LOC101346985 LOC101346985 LOC101344099 LOC101344099 LOC101341715 LOC101341715 LOC101352607 LOC101352607 LOC101341158 LOC101341158 LOC101357556 LOC101357556 LOC101361433 LOC101361433 LOC101344111 LOC101344111 LOC101346041 LOC101346041 LOC101342003 LOC101342003 LOC101345532 LOC101345532 LOC101356881 LOC101356881 LOC101355276 LOC101355276 LOC101345125 LOC101345125 LOC101351498 LOC101351498 LOC101348601 LOC101348601 LOC101351856 LOC101351856 LOC101346534 LOC101346534 LOC101349967 LOC101349967 LOC101342008 LOC101342008 LOC101361961 LOC101361961 LOC101344242 LOC101344242 LOC101352801 LOC101352801 LOC101353682 LOC101353682 LOC101350837 LOC101350837 LOC101351964 LOC101351964 LOC101343540 LOC101343540 LOC101348029 LOC101348029 LOC101361375 LOC101361375 LOC101347192 LOC101347192 LOC101356404 LOC101356404 LOC101358526 LOC101358526 LOC101356255 LOC101356255 LOC101346441 LOC101346441
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101341781Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
LOC101351897Catenin beta-1. (781 aa)
LOC101341952Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (355 aa)
LOC101357085Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2179 aa)
LOC101342638cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
LOC101352074Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (653 aa)
LOC101354636Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family. (508 aa)
LOC101348142Neuroendocrine secretory protein 55. (248 aa)
LOC101342296Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (335 aa)
LOC101357348Transcription factor E2F1. (461 aa)
LOC101358375Phosphodiesterase. (840 aa)
LOC101348322Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (719 aa)
LOC101361662G1/S-specific cyclin-E2; Belongs to the cyclin family. (406 aa)
LOC101341387Cyclin-dependent kinase 4 inhibitor C. (168 aa)
LOC101344702Corticoliberin. (194 aa)
LOC101350704Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
LOC101344705Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC101345867Cyclin-dependent kinase inhibitor 2A. (152 aa)
LOC101351137Cyclin-dependent kinase 4 inhibitor B. (138 aa)
LOC101349186Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
LOC101345870Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2178 aa)
LOC101343587WD repeat-containing protein 5B. (330 aa)
LOC101345357Cyclic AMP-dependent transcription factor ATF-4. (352 aa)
LOC101347495Axin-2. (839 aa)
LOC101342156Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
LOC101340626Corticotropin-releasing factor receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (415 aa)
LOC101347661Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (566 aa)
LOC101343332Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC101357207Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (521 aa)
LOC101341899Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LOC101343945Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
LOC101354922Phosphodiesterase. (933 aa)
LOC101359885Steroidogenic factor 1 isoform X1. (461 aa)
LOC101349879Fumarate hydratase, mitochondrial. (508 aa)
LOC101347671Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
LOC101360142Segment polarity protein dishevelled homolog DVL-2. (736 aa)
LOC101341737Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (448 aa)
LOC101350297Aryl-hydrocarbon-interacting protein-like 1. (328 aa)
LOC101355952Retinoblastoma-associated protein isoform X3. (938 aa)
LOC101340818Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1975 aa)
LOC101349290Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
LOC101350203Pro-opiomelanocortin. (270 aa)
LOC101355436Potassium channel subfamily K member. (400 aa)
LOC101345798Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
LOC101358150Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
LOC101347003Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
LOC101341078Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC101345890Guanine nucleotide-binding protein subunit alpha-11. (354 aa)
LOC101355964Cyclic AMP-responsive element-binding protein 3-like protein 3. (483 aa)
LOC101346660Adenomatous polyposis coli protein 2. (1344 aa)
LOC101348360Calcium release-activated calcium channel protein 1. (218 aa)
LOC101346145Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC1013583253 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2; Belongs to the 3-beta-HSD family. (373 aa)
LOC101348949Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
LOC101360249Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (544 aa)
LOC101360334Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (977 aa)
LOC101353504Dexamethasone-induced Ras-related protein 1. (280 aa)
LOC101351340Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa)
LOC101359902Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
LOC101342423Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
LOC101360945Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2109 aa)
LOC101343271Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC101362049Segment polarity protein dishevelled homolog DVL-3. (716 aa)
LOC101340313Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LOC101357820Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
LOC1013522961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC101349137Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
LOC101359651Neutral cholesterol ester hydrolase 1. (408 aa)
LOC101340320Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
LOC101359745G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
LOC101343025Peptidylprolyl isomerase. (330 aa)
LOC101356822Receptor protein-tyrosine kinase. (1156 aa)
LOC101345396Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
LOC101360002Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (461 aa)
LOC101359224Calcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (486 aa)
LOC101346679Transcription factor E2F3 isoform X1. (459 aa)
LOC101359840Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
LOC101353435Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1; Belongs to the protein kinase superfamily. (499 aa)
LOC101354868Adenylate cyclase type 1. (903 aa)
LOC101359317Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
LOC101360614Armadillo repeat-containing protein 5. (934 aa)
LOC101340589Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
LOC101353082Calcium/calmodulin-dependent protein kinase type II subunit beta. (655 aa)
LOC101359144Melanocortin-2 receptor accessory protein. (156 aa)
LOC101360273Cyclin-dependent kinase inhibitor 1B. (198 aa)
LOC101349413Potassium channel subfamily K member 2 isoform X1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
LOC101361647Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (472 aa)
LOC101352160Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
LOC101349243Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC101354125Cytochrome P450 11B1, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (502 aa)
LOC101351717Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LOC101341696Transcription factor 7-like 1. (463 aa)
LOC101344076Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
LOC101343291WD repeat-containing protein 5. (334 aa)
LOC101346092Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
LOC101353099Histone-lysine N-methyltransferase 2D. (5544 aa)
LOC101344337Cyclic AMP-responsive element-binding protein 3-like protein 4. (395 aa)
LOC101344186Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
LOC101354392Inositol 1,4,5-trisphosphate receptor type 3. (2670 aa)
LOC101348994Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (650 aa)
LOC101345427Adrenocorticotropic hormone receptor. (300 aa)
LOC101350438Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
LOC101359524Steroid 21-hydroxylase; Belongs to the cytochrome P450 family. (494 aa)
LOC101359884Cyclic AMP-dependent transcription factor ATF-2. (455 aa)
LOC101354427Corticotropin-releasing factor receptor 2; Belongs to the G-protein coupled receptor 2 family. (277 aa)
LOC101353421Serine/threonine-protein kinase B-raf. (743 aa)
LOC101348129Ras-related protein Rap-1b. (184 aa)
LOC101346513Menin isoform X1. (615 aa)
LOC101359783Cyclic AMP-dependent transcription factor ATF-6 beta. (711 aa)
LOC101358885Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
LOC101356576Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
LOC101361837Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (922 aa)
LOC101348995cAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
LOC101351576Angiotensinogen; Belongs to the serpin family. (491 aa)
LOC101340519Aryl hydrocarbon receptor nuclear translocator. (789 aa)
LOC101349790Transcription factor Sp1. (937 aa)
LOC101359618Phosphodiesterase. (881 aa)
LOC101350636Retinoblastoma-binding protein 5 isoform X1. (549 aa)
LOC101346985Axin-1 isoform X1. (878 aa)
LOC101344099G1/S-specific cyclin-E1; Belongs to the cyclin family. (395 aa)
LOC101341715Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
LOC101352607Cyclic AMP-responsive element-binding protein 3. (377 aa)
LOC101341158Adenomatous polyposis coli protein isoform X1. (2856 aa)
LOC101357556Transcription factor E2F2. (434 aa)
LOC101361433Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
LOC101344111Voltage-dependent T-type calcium channel subunit alpha-1H. (2355 aa)
LOC101346041Adenylate cyclase type 5. (1265 aa)
LOC101342003Low-density lipoprotein receptor. (866 aa)
LOC101345532Transcription factor 7-like 2 isoform X1. (381 aa)
LOC101356881Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
LOC101355276Cyclin-dependent kinase 4 isoform X1; Belongs to the protein kinase superfamily. (381 aa)
LOC101345125Lymphoid enhancer-binding factor 1 isoform X1. (414 aa)
LOC101351498Aryl hydrocarbon receptor. (844 aa)
LOC101348601Ubiquitin carboxyl-terminal hydrolase 8 isoform X1; Belongs to the peptidase C19 family. (1115 aa)
LOC101351856Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2379 aa)
LOC101346534Inositol 1,4,5-trisphosphate receptor type 1. (2715 aa)
LOC101349967Phosphoinositide phospholipase C. (909 aa)
LOC101342008Cyclin-dependent kinase inhibitor 1 isoform X1. (189 aa)
LOC101361961Calcium/calmodulin-dependent protein kinase type II subunit gamma. (821 aa)
LOC1013442421-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1226 aa)
LOC101352801Ras-related protein Rap-1A. (184 aa)
LOC101353682Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa)
LOC101350837LOW QUALITY PROTEIN: transcription factor 7. (493 aa)
LOC101351964Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (4002 aa)
LOC101343540Scavenger receptor class B member 1; Belongs to the CD36 family. (507 aa)
LOC101348029set1/Ash2 histone methyltransferase complex subunit ASH2. (402 aa)
LOC1013613751-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1166 aa)
LOC101347192Guanine nucleotide-binding protein G(Q) subunit alpha isoform X3. (381 aa)
LOC101356404Inositol 1,4,5-trisphosphate receptor type 2. (2441 aa)
LOC101358526Mitogen-activated protein kinase 1. (263 aa)
LOC101356255pre-B-cell leukemia transcription factor 1 isoform X1. (430 aa)
LOC101346441Nuclear receptor subfamily 4 group A member 1 isoform X1. (649 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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