STRINGSTRING
LOC101356840 LOC101356840 LOC101340600 LOC101340600 LOC101361653 LOC101361653 LOC101360631 LOC101360631 LOC101341290 LOC101341290 LOC101346710 LOC101346710 LOC101357016 LOC101357016 LOC101352434 LOC101352434 LOC101351035 LOC101351035 LOC101349186 LOC101349186 LOC101349610 LOC101349610 LOC101344618 LOC101344618 LOC101355428 LOC101355428 LOC101345102 LOC101345102 LOC101360313 LOC101360313 LOC101347746 LOC101347746 LOC101344372 LOC101344372 LOC101343332 LOC101343332 LOC101340368 LOC101340368 LOC101343767 LOC101343767 LOC101342743 LOC101342743 LOC101351755 LOC101351755 LOC101342748 LOC101342748 LOC101361092 LOC101361092 LOC101355353 LOC101355353 LOC101361943 LOC101361943 LOC101360493 LOC101360493 LOC101342167 LOC101342167 LOC101351590 LOC101351590 LOC101341326 LOC101341326 LOC101354176 LOC101354176 LOC101361946 LOC101361946 LOC101358234 LOC101358234 LOC101346746 LOC101346746 LOC101341078 LOC101341078 LOC101343514 LOC101343514 LOC101361614 LOC101361614 LOC101350066 LOC101350066 LOC101361872 LOC101361872 LOC101352466 LOC101352466 LOC101340836 LOC101340836 LOC101351866 LOC101351866 LOC101355711 LOC101355711 LOC101348880 LOC101348880 LOC101354947 LOC101354947 LOC101352388 LOC101352388 LOC101358515 LOC101358515 LOC101346849 LOC101346849 LOC101343804 LOC101343804 LOC101349224 LOC101349224 LOC101340853 LOC101340853 LOC101340589 LOC101340589 LOC101360180 LOC101360180 LOC101355809 LOC101355809 LOC101346861 LOC101346861 LOC101343550 LOC101343550 LOC101346094 LOC101346094 LOC101351734 LOC101351734 LOC101347574 LOC101347574 LOC101354911 LOC101354911 LOC101356099 LOC101356099 LOC101358871 LOC101358871 LOC101357919 LOC101357919 LOC101342555 LOC101342555 LOC101343469 LOC101343469 LOC101359059 LOC101359059 LOC101343546 LOC101343546 LOC101359597 LOC101359597 LOC111819117 LOC111819117 LOC101350273 LOC101350273 LOC101361835 LOC101361835 LOC101358037 LOC101358037 LOC101347479 LOC101347479 TNF TNF LOC101345959 LOC101345959 LOC101340624 LOC101340624 LOC101340808 LOC101340808 LOC101355146 LOC101355146 LOC101357269 LOC101357269 LOC101344286 LOC101344286 LOC101353470 LOC101353470 LOC101350197 LOC101350197 LOC101356110 LOC101356110 LOC101360841 LOC101360841 LOC101344716 LOC101344716 LOC101348260 LOC101348260 LOC101356962 LOC101356962 LOC101347509 LOC101347509 LOC111820845 LOC111820845 LOC101349700 LOC101349700 LOC101347632 LOC101347632 LOC101356054 LOC101356054 LOC101347350 LOC101347350 LOC101340374 LOC101340374 LOC101345902 LOC101345902 LOC101357217 LOC101357217 LOC101361451 LOC101361451 LOC101359297 LOC101359297 LOC101358678 LOC101358678 LOC101341934 LOC101341934 LOC101348449 LOC101348449 LOC101342429 LOC101342429 LOC101351256 LOC101351256 LOC101345331 LOC101345331 LOC101359658 LOC101359658 LOC101343031 LOC101343031 LOC101350744 LOC101350744 LOC105756611 LOC105756611 LOC101348624 LOC101348624 LOC101347192 LOC101347192 LOC101358090 LOC101358090 LOC101361706 LOC101361706 LOC101351714 LOC101351714 LOC101358526 LOC101358526 LOC101355488 LOC101355488 LOC101358886 LOC101358886 LOC101361555 LOC101361555 IL1B IL1B LOC101343648 LOC101343648 LOC101360881 LOC101360881 LOC101348301 LOC101348301 LOC101353271 LOC101353271 LOC101344591 LOC101344591 LOC101355751 LOC101355751
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101356840Transforming protein RhoA. (193 aa)
LOC101340600Ribosomal protein S6 kinase. (733 aa)
LOC101361653Transcription factor AP-1; Belongs to the bZIP family. (329 aa)
LOC101360631NLR family CARD domain-containing protein 4 isoform X1. (1024 aa)
LOC101341290Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
LOC101346710ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
LOC101357016Proto-oncogene c-Fos. (380 aa)
LOC101352434Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1074 aa)
LOC101351035Phosphatidylinositol 3-kinase regulatory subunit gamma. (462 aa)
LOC101349186Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
LOC101349610Interferon beta. (188 aa)
LOC101344618TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
LOC101355428Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
LOC101345102Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1. (515 aa)
LOC101360313Ras-related C3 botulinum toxin substrate 3. (188 aa)
LOC101347746Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC101344372Actin, cytoplasmic 2. (375 aa)
LOC101343332Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC101340368Rho guanine nucleotide exchange factor 28. (1404 aa)
LOC101343767Actin-related protein 3 isoform X1; Belongs to the actin family. (418 aa)
LOC101342743Interleukin-10. (178 aa)
LOC101351755Integrin alpha-4; Belongs to the integrin alpha chain family. (1032 aa)
LOC101342748Adapter molecule crk isoform X1. (304 aa)
LOC101361092Fibronectin isoform X3. (2477 aa)
LOC101355353NF-kappa-B inhibitor alpha. (314 aa)
LOC101361943Cell division control protein 42 homolog isoform X1. (191 aa)
LOC101360493Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC101342167Src kinase-associated phosphoprotein 2. (360 aa)
LOC101351590Interleukin-6. (237 aa)
LOC101341326Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (314 aa)
LOC101354176WAS/WASL-interacting protein family member 3. (489 aa)
LOC101361946WAS/WASL-interacting protein family member 2. (439 aa)
LOC101358234TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (703 aa)
LOC101346746Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
LOC101341078Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC101343514Ribosomal protein S6 kinase. (747 aa)
LOC101361614Mitogen-activated protein kinase. (283 aa)
LOC101350066LOW QUALITY PROTEIN: ARF GTPase-activating protein GIT2. (764 aa)
LOC101361872Mitogen-activated protein kinase. (366 aa)
LOC101352466Mitogen-activated protein kinase. (595 aa)
LOC101340836LIM domain kinase 1 isoform X1. (647 aa)
LOC101351866Nuclear factor NF-kappa-B p105 subunit isoform X1. (997 aa)
LOC101355711Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
LOC101348880Interferon regulatory factor 3. (421 aa)
LOC101354947Protein-tyrosine kinase 2-beta isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
LOC101352388Ribosomal protein S6 kinase. (740 aa)
LOC101358515Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (106 aa)
LOC101346849Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101343804Phosphatidylinositol 3-kinase regulatory subunit beta. (729 aa)
LOC101349224Interleukin-1 receptor-associated kinase 4 isoform X1. (463 aa)
LOC101340853Engulfment and cell motility protein 1. (719 aa)
LOC101340589Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
LOC101360180Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (174 aa)
LOC101355809Crk-like protein. (303 aa)
LOC101346861Breast cancer anti-estrogen resistance protein 1. (840 aa)
LOC101343550Guanine nucleotide exchange factor VAV2. (839 aa)
LOC101346094Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
LOC101351734Mitogen-activated protein kinase. (464 aa)
LOC101347574NF-kappa-B essential modulator isoform X1. (421 aa)
LOC101354911TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (509 aa)
LOC101356099Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC101358871C-C motif chemokine. (141 aa)
LOC101357919Apoptosis-associated speck-like protein containing a CARD. (205 aa)
LOC101342555Tyrosine-protein kinase. (542 aa)
LOC101343469T-cell surface glycoprotein CD8 alpha chain isoform X1. (241 aa)
LOC101359059Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (933 aa)
LOC101343546Mitogen-activated protein kinase. (427 aa)
LOC1013595971-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
LOC111819117Uncharacterized protein LOC111819117. (244 aa)
LOC101350273Interleukin-1 receptor-associated kinase 1. (826 aa)
LOC101361835Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (588 aa)
LOC101358037Tyrosine-protein kinase. (542 aa)
LOC101347479Serine/threonine-protein kinase N1. (951 aa)
TNFTumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (234 aa)
LOC101345959Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1405 aa)
LOC101340624Actin-related protein 3B isoform X3; Belongs to the actin family. (418 aa)
LOC101340808Integrin alpha-5; Belongs to the integrin alpha chain family. (1062 aa)
LOC101355146TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
LOC101357269Lymphocyte cytosolic protein 2. (534 aa)
LOC101344286Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (334 aa)
LOC101353470Toll-like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
LOC101350197Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (393 aa)
LOC101356110Pyrin isoform X1. (712 aa)
LOC101360841WAS/WASL-interacting protein family member 1. (507 aa)
LOC101344716Ribosomal protein S6 kinase. (770 aa)
LOC101348260wiskott-Aldrich syndrome protein isoform X1. (534 aa)
LOC101356962Dedicator of cytokinesis protein 1; Belongs to the DOCK family. (1865 aa)
LOC101347509Proto-oncogene vav. (841 aa)
LOC111820845LOW QUALITY PROTEIN: uncharacterized protein LOC111820845. (355 aa)
LOC101349700Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (390 aa)
LOC101347632Tyrosine-protein kinase. (617 aa)
LOC101356054Ras-related C3 botulinum toxin substrate 1. (148 aa)
LOC101347350Mitogen-activated protein kinase. (321 aa)
LOC101340374wiskott-Aldrich syndrome protein family member 2. (498 aa)
LOC101345902Serine/threonine-protein kinase TBK1 isoform X1. (758 aa)
LOC101357217Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (703 aa)
LOC101361451LOW QUALITY PROTEIN: uncharacterized protein LOC101361451. (608 aa)
LOC101359297Caspase-1; Belongs to the peptidase C14A family. (405 aa)
LOC101358678Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1082 aa)
LOC101341934Rho guanine nucleotide exchange factor 7 isoform X1. (721 aa)
LOC101348449Rho-related GTP-binding protein RhoG. (191 aa)
LOC101342429Uncharacterized protein LOC101342429. (266 aa)
LOC101351256Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
LOC101345331TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
LOC101359658Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
LOC101343031NACHT, LRR and PYD domains-containing protein 3 isoform X1. (1064 aa)
LOC101350744Low affinity immunoglobulin gamma Fc region receptor III-like isoform X1. (265 aa)
LOC105756611Uncharacterized protein LOC105756611. (256 aa)
LOC101348624Interleukin-18. (201 aa)
LOC101347192Guanine nucleotide-binding protein G(Q) subunit alpha isoform X3. (381 aa)
LOC101358090Rho guanine nucleotide exchange factor 12 isoform X1. (1550 aa)
LOC101361706Transcription factor p65. (538 aa)
LOC101351714Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
LOC101358526Mitogen-activated protein kinase 1. (263 aa)
LOC101355488Phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1. (440 aa)
LOC101358886T-cell surface glycoprotein CD8 beta chain. (211 aa)
LOC101361555Neural Wiskott-Aldrich syndrome protein. (408 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (262 aa)
LOC101343648T-cell surface glycoprotein CD4 isoform X1. (488 aa)
LOC101360881Integrin beta; Belongs to the integrin beta chain family. (832 aa)
LOC101348301FYN-binding protein 1 isoform X1. (865 aa)
LOC101353271Guanine nucleotide exchange factor VAV3 isoform X1. (850 aa)
LOC101344591Engulfment and cell motility protein 2 isoform X1. (720 aa)
LOC101355751Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (930 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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