STRINGSTRING
LOC101357840 LOC101357840 LOC101351897 LOC101351897 LOC101356840 LOC101356840 LOC101361653 LOC101361653 LOC101346702 LOC101346702 LOC101353013 LOC101353013 LOC101359592 LOC101359592 LOC101357016 LOC101357016 LOC101358028 LOC101358028 LOC101347392 LOC101347392 LOC101351035 LOC101351035 LOC101359953 LOC101359953 LOC101349186 LOC101349186 LOC101355428 LOC101355428 LOC101359012 LOC101359012 LOC101347495 LOC101347495 LOC101348672 LOC101348672 LOC101360313 LOC101360313 LOC101359617 LOC101359617 LOC101347746 LOC101347746 LOC101343332 LOC101343332 LOC101344857 LOC101344857 LOC101347669 LOC101347669 LOC101360493 LOC101360493 LOC101354258 LOC101354258 LOC101347000 LOC101347000 LOC101354510 LOC101354510 LOC101341078 LOC101341078 LOC101346660 LOC101346660 LOC101348099 LOC101348099 LOC101345213 LOC101345213 LOC101347007 LOC101347007 LOC101359817 LOC101359817 LOC101344230 LOC101344230 LOC101356564 LOC101356564 LOC101343535 LOC101343535 LOC101359745 LOC101359745 LOC101354107 LOC101354107 LOC101356822 LOC101356822 LOC101347525 LOC101347525 LOC101346849 LOC101346849 LOC101343808 LOC101343808 LOC101343804 LOC101343804 LOC101361119 LOC101361119 LOC101351271 LOC101351271 LOC101340589 LOC101340589 LOC101349998 LOC101349998 LOC101341696 LOC101341696 LOC101351734 LOC101351734 LOC101341201 LOC101341201 LOC101348656 LOC101348656 LOC101356196 LOC101356196 LOC101356099 LOC101356099 LOC101355182 LOC101355182 LOC101352321 LOC101352321 LOC101354940 LOC101354940 LOC101345932 LOC101345932 LOC101353421 LOC101353421 LOC101351825 LOC101351825 LOC101343546 LOC101343546 LOC101348205 LOC101348205 LOC101342129 LOC101342129 LOC101342804 LOC101342804 LOC101354307 LOC101354307 LOC101346985 LOC101346985 LOC101351589 LOC101351589 LOC101341158 LOC101341158 LOC101350197 LOC101350197 LOC101349786 LOC101349786 LOC101348938 LOC101348938 LOC101358048 LOC101358048 LOC101340375 LOC101340375 LOC101345532 LOC101345532 LOC101355918 LOC101355918 LOC101351852 LOC101351852 LOC101356054 LOC101356054 LOC101345125 LOC101345125 LOC101355971 LOC101355971 LOC101355103 LOC101355103 LOC101358678 LOC101358678 LOC101348022 LOC101348022 LOC101342008 LOC101342008 LOC101358763 LOC101358763 LOC101346158 LOC101346158 LOC101359658 LOC101359658 LOC101350837 LOC101350837 LOC101352047 LOC101352047 LOC101358526 LOC101358526 LOC101349734 LOC101349734 LOC101342543 LOC101342543
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101357840RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
LOC101351897Catenin beta-1. (781 aa)
LOC101356840Transforming protein RhoA. (193 aa)
LOC101361653Transcription factor AP-1; Belongs to the bZIP family. (329 aa)
LOC101346702DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
LOC101353013Growth arrest and DNA damage-inducible protein GADD45 alpha. (162 aa)
LOC101359592Son of sevenless homolog 1 isoform X1. (1333 aa)
LOC101357016Proto-oncogene c-Fos. (380 aa)
LOC101358028Transforming growth factor beta-3. (457 aa)
LOC101347392Son of sevenless homolog 2 isoform X1. (1328 aa)
LOC101351035Phosphatidylinositol 3-kinase regulatory subunit gamma. (462 aa)
LOC101359953Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
LOC101349186Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
LOC101355428Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
LOC101359012Growth factor receptor-bound protein 2. (176 aa)
LOC101347495Axin-2. (839 aa)
LOC101348672Baculoviral IAP repeat-containing protein 5. (142 aa)
LOC101360313Ras-related C3 botulinum toxin substrate 3. (188 aa)
LOC101359617DNA polymerase kappa isoform X1. (865 aa)
LOC101347746Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC101343332Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC101344857Mothers against decapentaplegic homolog. (425 aa)
LOC101347669Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LOC101360493Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC101354258TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LOC101347000DNA mismatch repair protein Mlh1. (758 aa)
LOC101354510Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
LOC101341078Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC101346660Adenomatous polyposis coli protein 2. (1344 aa)
LOC101348099Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa)
LOC101345213Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
LOC101347007Apoptosis regulator Bcl-2 isoform X1. (229 aa)
LOC101359817Netrin receptor DCC. (897 aa)
LOC101344230GTPase NRas isoform X1. (189 aa)
LOC101356564Apoptosis regulator BAX. (173 aa)
LOC101343535Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
LOC101359745G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
LOC101354107Ras-related protein Ral-A. (206 aa)
LOC101356822Receptor protein-tyrosine kinase. (1156 aa)
LOC101347525GTPase KRas isoform X3. (227 aa)
LOC101346849Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101343808Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
LOC101343804Phosphatidylinositol 3-kinase regulatory subunit beta. (729 aa)
LOC101361119Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa)
LOC101351271Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC101340589Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
LOC101349998DNA damage-binding protein 2. (464 aa)
LOC101341696Transcription factor 7-like 1. (463 aa)
LOC101351734Mitogen-activated protein kinase. (464 aa)
LOC101341201Bcl-2 homologous antagonist/killer. (212 aa)
LOC101348656Mothers against decapentaplegic homolog. (467 aa)
LOC101356196Amphiregulin. (254 aa)
LOC101356099Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC101355182LOW QUALITY PROTEIN: cytochrome c, testis-specific-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC101352321LOW QUALITY PROTEIN: DCC-interacting protein 13-alpha. (625 aa)
LOC101354940LOW QUALITY PROTEIN: cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC101345932DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1358 aa)
LOC101353421Serine/threonine-protein kinase B-raf. (743 aa)
LOC101351825Ral guanine nucleotide dissociation stimulator-like. (613 aa)
LOC101343546Mitogen-activated protein kinase. (427 aa)
LOC101348205LOW QUALITY PROTEIN: ral guanine nucleotide dissociation stimulator-like. (579 aa)
LOC101342129Ras-related protein Ral-B. (206 aa)
LOC101342804GTPase HRas isoform X1. (189 aa)
LOC101354307Caspase-3 isoform X1; Belongs to the peptidase C14A family. (277 aa)
LOC101346985Axin-1 isoform X1. (878 aa)
LOC101351589Serine/threonine-protein kinase A-Raf. (611 aa)
LOC101341158Adenomatous polyposis coli protein isoform X1. (2856 aa)
LOC101350197Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (393 aa)
LOC101349786Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
LOC101348938Ral guanine nucleotide dissociation stimulator isoform X1. (941 aa)
LOC101358048DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1106 aa)
LOC101340375Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC101345532Transcription factor 7-like 2 isoform X1. (381 aa)
LOC101355918Protransforming growth factor alpha isoform X1. (162 aa)
LOC101351852Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa)
LOC101356054Ras-related C3 botulinum toxin substrate 1. (148 aa)
LOC101345125Lymphoid enhancer-binding factor 1 isoform X1. (414 aa)
LOC101355971Pro-epidermal growth factor. (1109 aa)
LOC101355103Caspase-9; Belongs to the peptidase C14A family. (448 aa)
LOC101358678Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1082 aa)
LOC101348022Bcl-2-binding component 3. (210 aa)
LOC101342008Cyclin-dependent kinase inhibitor 1 isoform X1. (189 aa)
LOC101358763Mothers against decapentaplegic homolog. (552 aa)
LOC101346158Proepiregulin. (98 aa)
LOC101359658Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
LOC101350837LOW QUALITY PROTEIN: transcription factor 7. (493 aa)
LOC101352047Bcl2-associated agonist of cell death. (167 aa)
LOC101358526Mitogen-activated protein kinase 1. (263 aa)
LOC101349734LOW QUALITY PROTEIN: ral guanine nucleotide dissociation stimulator-like. (585 aa)
LOC101342543Transforming growth factor beta; Belongs to the TGF-beta family. (392 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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