64 items (Trichechus manatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101358535	Dystroglycan. (893 aa)
	LOC101356284	Coxsackievirus and adenovirus receptor. (365 aa)
	LOC101351045	Tyrosine-protein kinase. (1182 aa)
	LOC101355428	Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
	LOC101360313	Ras-related C3 botulinum toxin substrate 3. (188 aa)
	LOC101344372	Actin, cytoplasmic 2. (375 aa)
	LOC101341732	Tyrosine-protein kinase. (1142 aa)
	LOC101354843	Alpha-sarcoglycan isoform X1. (387 aa)
	LOC101344302	Caspase-8 isoform X1; Belongs to the peptidase C14A family. (477 aa)
	LOC101343092	T-cell-specific surface glycoprotein CD28 isoform X1. (256 aa)
	LOC101354525	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
	LOC101351876	Beta-sarcoglycan. (319 aa)
	LOC101359745	G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
	LOC101349050	Integrin beta. (773 aa)
	LOC101351271	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	LOC101357999	Dystrophin. (3658 aa)
	LOC101342788	Gamma-sarcoglycan. (291 aa)
	LOC101355641	Integrin alpha-L; Belongs to the integrin alpha chain family. (1170 aa)
	LOC101345849	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	LOC101353289	Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1860 aa)
	LOC101343573	HLA class II histocompatibility antigen, DM beta chain. (178 aa)
	LOC101345522	HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (254 aa)
	LOC101340887	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family. (363 aa)
	LOC101345267	HLA class II histocompatibility antigen, DQ alpha 2 chain-like. (255 aa)
	LOC101348755	HLA class II histocompatibility antigen, DP alpha 1 chain-like; Belongs to the MHC class II family. (207 aa)
	LOC101356509	Laminin subunit alpha-2. (2959 aa)
	LOC101355182	LOW QUALITY PROTEIN: cytochrome c, testis-specific-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	LOC101354940	LOW QUALITY PROTEIN: cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	LOC101347367	Laminin subunit alpha-1. (2407 aa)
	LOC101359320	HLA class I histocompatibility antigen, A-80 alpha chain-like; Belongs to the MHC class I family. (219 aa)
	LOC101346365	Class I histocompatibility antigen, Gogo-B*0103 alpha chain-like; Belongs to the MHC class I family. (413 aa)
	LOC101342571	HLA class II histocompatibility antigen, DP beta 1 chain-like. (224 aa)
	LOC101342567	HLA class II histocompatibility antigen, DP beta 1 chain. (258 aa)
	LOC111819117	Uncharacterized protein LOC111819117. (244 aa)
	LOC101346884	HLA class I histocompatibility antigen, A-80 alpha chain-like. (180 aa)
	LOC101347138	HLA class I histocompatibility antigen, B-40 alpha chain-like isoform X1; Belongs to the MHC class I family. (374 aa)
	LOC101345854	Class I histocompatibility antigen, Gogo-B*0101 alpha chain-like isoform X1; Belongs to the MHC class I family. (357 aa)
	LOC101344101	LOW QUALITY PROTEIN: boLa class II histocompatibility antigen, DQB*0101 beta chain-like. (259 aa)
	LOC101342817	RLA class II histocompatibility antigen, DP alpha-1 chain isoform X1; Belongs to the MHC class II family. (262 aa)
	LOC101354307	Caspase-3 isoform X1; Belongs to the peptidase C14A family. (277 aa)
	LOC101350180	Patr class I histocompatibility antigen, B-1 alpha chain-like isoform X2; Belongs to the MHC class I family. (226 aa)
	LOC101343312	HLA class II histocompatibility antigen, DM alpha chain isoform X1; Belongs to the MHC class II family. (285 aa)
	LOC101343065	HLA class II histocompatibility antigen, DO alpha chain. (156 aa)
	LOC101345015	boLa class II histocompatibility antigen, DQB*0101 beta chain-like. (269 aa)
	LOC101361245	LOW QUALITY PROTEIN: DLA class II histocompatibility antigen, DR-1 beta chain-like. (260 aa)
	LOC101349613	T-lymphocyte activation antigen CD80 isoform X1. (344 aa)
	LOC101349002	Delta-sarcoglycan. (216 aa)
	LOC101347585	T-lymphocyte activation antigen CD86 isoform X1. (311 aa)
	LOC101358829	Complement decay-accelerating factor isoform X1. (373 aa)
	LOC101340375	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	LOC101342926	Eukaryotic translation initiation factor 4 gamma 3 isoform X1. (1665 aa)
	LOC101343257	Intercellular adhesion molecule 1. (345 aa)
	LOC111820845	LOW QUALITY PROTEIN: uncharacterized protein LOC111820845. (355 aa)
	LOC101356054	Ras-related C3 botulinum toxin substrate 1. (148 aa)
	LOC101355103	Caspase-9; Belongs to the peptidase C14A family. (448 aa)
	LOC101361451	LOW QUALITY PROTEIN: uncharacterized protein LOC101361451. (608 aa)
	LOC101342429	Uncharacterized protein LOC101342429. (266 aa)
	LOC101350361	Eukaryotic translation initiation factor 4 gamma 2 isoform X1. (701 aa)
	LOC101356396	BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (200 aa)
	LOC101358077	Eukaryotic translation initiation factor 4 gamma 1 isoform X1. (1597 aa)
	LOC105756611	Uncharacterized protein LOC105756611. (256 aa)
	LOC101349740	HLA class I histocompatibility antigen, Cw-12 alpha chain-like; Belongs to the MHC class I family. (191 aa)
	LOC101345594	Tumor necrosis factor receptor superfamily member 5 isoform X1. (283 aa)
	LOC101345748	H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1; Belongs to the MHC class I family. (406 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101340375	LOC101344302	A0A2Y9R150	A0A2Y9DP28	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase-8 isoform X1; Belongs to the peptidase C14A family.	0.422
LOC101340375	LOC101354307	A0A2Y9R150	A0A2Y9QML3	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase-3 isoform X1; Belongs to the peptidase C14A family.	0.964
LOC101340375	LOC101355103	A0A2Y9R150	A0A2Y9R8L3	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase-9; Belongs to the peptidase C14A family.	0.978
LOC101340887	LOC101342429	A0A2Y9ECU2	A0A2Y9RE44	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	Uncharacterized protein LOC101342429.	0.734
LOC101340887	LOC101345748	A0A2Y9ECU2	A0A2Y9RYP1	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1; Belongs to the MHC class I family.	0.650
LOC101340887	LOC101345854	A0A2Y9ECU2	A0A2Y9QHW4	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	Class I histocompatibility antigen, Gogo-B*0101 alpha chain-like isoform X1; Belongs to the MHC class I family.	0.653
LOC101340887	LOC101346365	A0A2Y9ECU2	A0A2Y9G244	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	Class I histocompatibility antigen, Gogo-B*0103 alpha chain-like; Belongs to the MHC class I family.	0.654
LOC101340887	LOC101346884	A0A2Y9ECU2	A0A2Y9QCX5	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	HLA class I histocompatibility antigen, A-80 alpha chain-like.	0.654
LOC101340887	LOC101347138	A0A2Y9ECU2	A0A2Y9QHV9	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	HLA class I histocompatibility antigen, B-40 alpha chain-like isoform X1; Belongs to the MHC class I family.	0.709
LOC101340887	LOC101349740	A0A2Y9ECU2	A0A2Y9RQB2	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	HLA class I histocompatibility antigen, Cw-12 alpha chain-like; Belongs to the MHC class I family.	0.653
LOC101340887	LOC101350180	A0A2Y9ECU2	A0A2Y9QNZ8	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	Patr class I histocompatibility antigen, B-1 alpha chain-like isoform X2; Belongs to the MHC class I family.	0.654
LOC101340887	LOC101359320	A0A2Y9ECU2	A0A2Y9G0S9	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	HLA class I histocompatibility antigen, A-80 alpha chain-like; Belongs to the MHC class I family.	0.656
LOC101340887	LOC101361451	A0A2Y9ECU2	A0A2Y9RBE8	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	LOW QUALITY PROTEIN: uncharacterized protein LOC101361451.	0.671
LOC101340887	LOC105756611	A0A2Y9ECU2	A0A2Y9RMD0	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	Uncharacterized protein LOC105756611.	0.734
LOC101340887	LOC111819117	A0A2Y9ECU2	A0A2Y9QC78	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	Uncharacterized protein LOC111819117.	0.779
LOC101340887	LOC111820845	A0A2Y9ECU2	A0A2Y9R4A8	Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family.	LOW QUALITY PROTEIN: uncharacterized protein LOC111820845.	0.819
LOC101341732	LOC101351045	A0A2Y9DJL9	A0A2Y9DE47	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.902
LOC101341732	LOC101355428	A0A2Y9DJL9	A0A2Y9DGA8	Tyrosine-protein kinase.	Ras-related C3 botulinum toxin substrate 2 isoform X1.	0.942
LOC101341732	LOC101356054	A0A2Y9DJL9	A0A2Y9R6N8	Tyrosine-protein kinase.	Ras-related C3 botulinum toxin substrate 1.	0.942
LOC101341732	LOC101360313	A0A2Y9DJL9	A0A2Y9DGZ2	Tyrosine-protein kinase.	Ras-related C3 botulinum toxin substrate 3.	0.942