STRINGSTRING
LOC101344988 LOC101344988 LOC101351897 LOC101351897 LOC101356840 LOC101356840 LOC101346612 LOC101346612 LOC101361653 LOC101361653 LOC101360368 LOC101360368 LOC101340607 LOC101340607 LOC101344762 LOC101344762 LOC101341290 LOC101341290 LOC101347888 LOC101347888 LOC101356019 LOC101356019 LOC101358809 LOC101358809 LOC101357016 LOC101357016 LOC101351035 LOC101351035 LOC101352955 LOC101352955 LOC101358817 LOC101358817 LOC101346291 LOC101346291 LOC101353895 LOC101353895 LOC101356954 LOC101356954 LOC101351050 LOC101351050 LOC101352963 LOC101352963 LOC101341641 LOC101341641 LOC101355428 LOC101355428 LOC101344115 LOC101344115 LOC101348507 LOC101348507 LOC101360313 LOC101360313 LOC101347746 LOC101347746 LOC101344372 LOC101344372 LOC101345785 LOC101345785 LOC101359355 LOC101359355 LOC101353397 LOC101353397 LOC101349955 LOC101349955 LOC101360493 LOC101360493 LOC101355438 LOC101355438 LOC101347507 LOC101347507 LOC101341332 LOC101341332 LOC101346746 LOC101346746 LOC101361614 LOC101361614 LOC101343785 LOC101343785 LOC101347007 LOC101347007 LOC101361872 LOC101361872 LOC101352466 LOC101352466 LOC101343104 LOC101343104 LOC101351866 LOC101351866 LOC101346669 LOC101346669 LOC101345047 LOC101345047 LOC101350991 LOC101350991 LOC101349561 LOC101349561 LOC101348626 LOC101348626 LOC101355634 LOC101355634 LOC101356570 LOC101356570 LOC101360260 LOC101360260 LOC101342109 LOC101342109 LOC101346849 LOC101346849 LOC101343804 LOC101343804 LOC101350086 LOC101350086 LOC101356496 LOC101356496 LOC101345146 LOC101345146 LOC101344666 LOC101344666 LOC101349230 LOC101349230 LOC101341605 LOC101341605 LOC101345400 LOC101345400 LOC101348896 LOC101348896 LOC101348971 LOC101348971 LOC101361386 LOC101361386 LOC101351010 LOC101351010 LOC101346429 LOC101346429 LOC101344166 LOC101344166 LOC101344077 LOC101344077 LOC101360022 LOC101360022 LOC101346094 LOC101346094 LOC101353976 LOC101353976 LOC101360282 LOC101360282 LOC101359155 LOC101359155 LOC101345849 LOC101345849 LOC101351734 LOC101351734 LOC101347574 LOC101347574 LOC101358030 LOC101358030 LOC101340888 LOC101340888 LOC101360033 LOC101360033 LOC101358487 LOC101358487 LOC101358846 LOC101358846 LOC101356099 LOC101356099 LOC101361121 LOC101361121 LOC101357691 LOC101357691 LOC101359469 LOC101359469 LOC105756334 LOC105756334 LOC101358871 LOC101358871 LOC101342555 LOC101342555 LOC101359728 LOC101359728 LOC101359111 LOC101359111 LOC101348117 LOC101348117 LOC101349477 LOC101349477 LOC101343546 LOC101343546 LOC101340508 LOC101340508 LOC101347312 LOC101347312 LOC101346784 LOC101346784 LOC101350431 LOC101350431 TNF TNF LOC101346473 LOC101346473 LOC101356953 LOC101356953 LOC101356462 LOC101356462 LOC101340441 LOC101340441 LOC101340967 LOC101340967 LOC101344286 LOC101344286 LOC101350197 LOC101350197 LOC101346475 LOC101346475 LOC101348356 LOC101348356 LOC101353551 LOC101353551 LOC101341920 LOC101341920 LOC101343257 LOC101343257 LOC101346907 LOC101346907 LOC101357210 LOC101357210 LOC101359450 LOC101359450 LOC101349700 LOC101349700 LOC101351852 LOC101351852 LOC101356054 LOC101356054 LOC101347350 LOC101347350 LOC101358013 LOC101358013 LOC101344340 LOC101344340 LOC101358678 LOC101358678 LOC101356221 LOC101356221 LOC101351256 LOC101351256 LOC101347126 LOC101347126 LOC101359658 LOC101359658 LOC101345299 LOC101345299 LOC101344569 LOC101344569 LOC101361706 LOC101361706 LOC101357584 LOC101357584 LOC101351714 LOC101351714 LOC101354535 LOC101354535 LOC101354972 LOC101354972 LOC101342274 LOC101342274 LOC101346957 LOC101346957 LOC101350098 LOC101350098 LOC101343375 LOC101343375 LOC101349733 LOC101349733 LOC101340258 LOC101340258 LOC101361989 LOC101361989 IL1B IL1B LOC101341867 LOC101341867
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101344988Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
LOC101351897Catenin beta-1. (781 aa)
LOC101356840Transforming protein RhoA. (193 aa)
LOC101346612Mitogen-activated protein kinase kinase kinase 5 isoform X1. (1374 aa)
LOC101361653Transcription factor AP-1; Belongs to the bZIP family. (329 aa)
LOC101360368Non-specific serine/threonine protein kinase. (552 aa)
LOC101340607Glutathione S-transferase omega-2 isoform X1; Belongs to the GST superfamily. (244 aa)
LOC101344762Small ubiquitin-related modifier 2-like. (74 aa)
LOC101341290Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
LOC101347888Matrix metalloproteinase-9. (724 aa)
LOC101356019Bone morphogenetic protein 4 isoform X1. (409 aa)
LOC101358809Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
LOC101357016Proto-oncogene c-Fos. (380 aa)
LOC101351035Phosphatidylinositol 3-kinase regulatory subunit gamma. (462 aa)
LOC101352955Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
LOC10135881772 kDa type IV collagenase. (659 aa)
LOC101346291Thioredoxin; Belongs to the thioredoxin family. (105 aa)
LOC101353895Myocyte-specific enhancer factor 2A isoform X1. (495 aa)
LOC101356954Neutrophil cytosol factor 2. (520 aa)
LOC101351050Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
LOC101352963Thioredoxin, mitochondrial. (166 aa)
LOC101341641Endoplasmin. (803 aa)
LOC101355428Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
LOC101344115Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
LOC101348507Integrin alpha-IIb; Belongs to the integrin alpha chain family. (1036 aa)
LOC101360313Ras-related C3 botulinum toxin substrate 3. (188 aa)
LOC101347746Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC101344372Actin, cytoplasmic 2. (375 aa)
LOC101345785Dual specificity mitogen-activated protein kinase kinase 5 isoform X1; Belongs to the protein kinase superfamily. (448 aa)
LOC101359355Integrin beta; Belongs to the integrin beta chain family. (742 aa)
LOC101353397Thrombomodulin. (582 aa)
LOC101349955Heat shock protein HSP 90-alpha isoform X1. (733 aa)
LOC101360493Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC101355438Cytochrome b-245 light chain isoform X1. (196 aa)
LOC101347507Small ubiquitin-related modifier. (101 aa)
LOC101341332E3 SUMO-protein ligase PIAS4. (516 aa)
LOC101346746Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
LOC101361614Mitogen-activated protein kinase. (283 aa)
LOC101343785Heat shock protein HSP 90-beta. (723 aa)
LOC101347007Apoptosis regulator Bcl-2 isoform X1. (229 aa)
LOC101361872Mitogen-activated protein kinase. (366 aa)
LOC101352466Mitogen-activated protein kinase. (595 aa)
LOC101343104Neutrophil cytosol factor 1 isoform X1. (391 aa)
LOC101351866Nuclear factor NF-kappa-B p105 subunit isoform X1. (997 aa)
LOC101346669Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (799 aa)
LOC101345047Cathepsin L1; Belongs to the peptidase C1 family. (334 aa)
LOC101350991Plasminogen activator; Belongs to the peptidase S1 family. (563 aa)
LOC101349561Endothelin-1. (207 aa)
LOC101348626Vascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
LOC101355634Krueppel-like factor 2. (195 aa)
LOC101356570Glutathione S-transferase P. (210 aa)
LOC101360260E-selectin. (611 aa)
LOC101342109Cathepsin L1; Belongs to the peptidase C1 family. (339 aa)
LOC101346849Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101343804Phosphatidylinositol 3-kinase regulatory subunit beta. (729 aa)
LOC101350086Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
LOC101356496Integrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1047 aa)
LOC101345146Vascular cell adhesion protein 1 isoform X1. (739 aa)
LOC101344666Platelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
LOC101349230Glutathione S-transferase theta-4; Belongs to the GST superfamily. (241 aa)
LOC101341605Heat shock protein HSP 90-alpha-like isoform X1. (726 aa)
LOC101345400Glutathione S-transferase theta-3-like. (172 aa)
LOC101348896Thioredoxin domain-containing protein 2. (242 aa)
LOC101348971Glutathione S-transferase theta-2B-like isoform X1; Belongs to the GST superfamily. (244 aa)
LOC101361386Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
LOC101351010Sequestosome-1 isoform X1. (440 aa)
LOC101346429Interferon gamma. (210 aa)
LOC101344166Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
LOC101344077Glutathione S-transferase. (218 aa)
LOC101360022Glutathione S-transferase A1; Belongs to the GST superfamily. (223 aa)
LOC101346094Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
LOC101353976C-type natriuretic peptide. (124 aa)
LOC101360282Glutathione S-transferase A4-like; Belongs to the GST superfamily. (222 aa)
LOC101359155Interleukin-1; Belongs to the IL-1 family. (268 aa)
LOC101345849Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
LOC101351734Mitogen-activated protein kinase. (464 aa)
LOC101347574NF-kappa-B essential modulator isoform X1. (421 aa)
LOC101358030Glutathione S-transferase. (217 aa)
LOC101340888LOW QUALITY PROTEIN: microsomal glutathione S-transferase 1. (155 aa)
LOC101360033Glutathione S-transferase. (227 aa)
LOC101358487Calmodulin; Belongs to the calmodulin family. (113 aa)
LOC101358846LOW QUALITY PROTEIN: calmodulin-like protein 3; Belongs to the calmodulin family. (148 aa)
LOC101356099Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC101361121LOW QUALITY PROTEIN: calmodulin-like protein 6. (188 aa)
LOC101357691Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
LOC101359469Small ubiquitin-related modifier. (95 aa)
LOC105756334Small ubiquitin-related modifier 2-like. (92 aa)
LOC101358871C-C motif chemokine. (141 aa)
LOC101342555Tyrosine-protein kinase. (542 aa)
LOC101359728Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (722 aa)
LOC101359111Calmodulin-like. (149 aa)
LOC101348117LOW QUALITY PROTEIN: heat shock protein HSP 90-alpha-like. (733 aa)
LOC101349477LOW QUALITY PROTEIN: glutathione S-transferase theta-1-like; Belongs to the GST superfamily. (240 aa)
LOC101343546Mitogen-activated protein kinase. (427 aa)
LOC101340508Glutathione S-transferase A4; Belongs to the GST superfamily. (222 aa)
LOC101347312Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
LOC101346784Non-specific serine/threonine protein kinase. (565 aa)
LOC101350431Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (197 aa)
TNFTumor necrosis factor isoform X1; Belongs to the tumor necrosis factor family. (234 aa)
LOC101346473Calmodulin-like protein 4. (153 aa)
LOC101356953Nitric oxide synthase; Produces nitric oxide (NO). (1214 aa)
LOC101356462Nuclear factor erythroid 2-related factor 2 isoform X1. (622 aa)
LOC101340441Platelet endothelial cell adhesion molecule isoform X1. (796 aa)
LOC101340967Argininosuccinate synthase isoform X2. (435 aa)
LOC101344286Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (334 aa)
LOC101350197Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (393 aa)
LOC101346475Myocyte-specific enhancer factor 2C isoform X1. (483 aa)
LOC101348356Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
LOC101353551Small ubiquitin-related modifier 2. (138 aa)
LOC101341920Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (637 aa)
LOC101343257Intercellular adhesion molecule 1. (345 aa)
LOC101346907Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
LOC101357210Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (541 aa)
LOC101359450Small ubiquitin-related modifier 2-like. (107 aa)
LOC101349700Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (390 aa)
LOC101351852Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa)
LOC101356054Ras-related C3 botulinum toxin substrate 1. (148 aa)
LOC101347350Mitogen-activated protein kinase. (321 aa)
LOC101358013Interleukin-1 receptor type 1. (572 aa)
LOC101344340Interleukin-1 receptor type 2 isoform X1. (417 aa)
LOC101358678Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1082 aa)
LOC101356221Kelch-like ECH-associated protein 1. (624 aa)
LOC101351256Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
LOC101347126Calmodulin-2 isoform X1; Belongs to the calmodulin family. (153 aa)
LOC101359658Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
LOC101345299Cathepsin L1-like; Belongs to the peptidase C1 family. (334 aa)
LOC101344569Microsomal glutathione S-transferase 2 isoform X1. (147 aa)
LOC101361706Transcription factor p65. (538 aa)
LOC101357584Microsomal glutathione S-transferase 3. (152 aa)
LOC101351714Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
LOC101354535NAD(P)H dehydrogenase [quinone] 1 isoform X1. (270 aa)
LOC101354972Glutathione S-transferase. (184 aa)
LOC101342274Small ubiquitin-related modifier. (114 aa)
LOC101346957Rho guanine nucleotide exchange factor 2 isoform X1. (1015 aa)
LOC101350098Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (312 aa)
LOC101343375Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LOC101349733LOW QUALITY PROTEIN: glutathione S-transferase theta-1-like; Belongs to the GST superfamily. (241 aa)
LOC101340258Glutathione S-transferase. (195 aa)
LOC101361989Glutathione S-transferase omega-1 isoform X1; Belongs to the GST superfamily. (271 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (262 aa)
LOC101341867Tumor necrosis factor receptor superfamily member 1A. (453 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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