STRINGSTRING
AGC41395.1 AGC41395.1 AGC41404.1 AGC41404.1 AGC41633.1 AGC41633.1 AGC41788.1 AGC41788.1 AGC41934.1 AGC41934.1 AGC41971.1 AGC41971.1 AGC42145.1 AGC42145.1 AGC42348.1 AGC42348.1 pgl pgl zwf zwf AGC42435.1 AGC42435.1 AGC42463.1 AGC42463.1 gpmI gpmI pckG pckG AGC42717.1 AGC42717.1 AGC42718.1 AGC42718.1 AGC42731.1 AGC42731.1 AGC43572.1 AGC43572.1 AGC43873.1 AGC43873.1 AGC44003.1 AGC44003.1 AGC44077.1 AGC44077.1 AGC44279.1 AGC44279.1 AGC44379.1 AGC44379.1 pdhA pdhA AGC44384.1 AGC44384.1 AGC44385.1 AGC44385.1 AGC44551.1 AGC44551.1 pgk pgk tpiA tpiA AGC44968.1 AGC44968.1 rbsK rbsK AGC45037.1 AGC45037.1 lipA lipA AGC45039.1 AGC45039.1 lipB lipB pfkA pfkA AGC45348.1 AGC45348.1 AGC45625.1 AGC45625.1 AGC45626.1 AGC45626.1 AGC45627.1 AGC45627.1 sucD sucD sucC sucC AGC45727.1 AGC45727.1 AGC45728.1 AGC45728.1 mdh mdh AGC45730.1 AGC45730.1 AGC45749.1 AGC45749.1 AGC45753.1 AGC45753.1 AGC45841.1 AGC45841.1 AGC46079.1 AGC46079.1 AGC46093.1 AGC46093.1 AGC46228.1 AGC46228.1 eno eno AGC46307.1 AGC46307.1 AGC46308.1 AGC46308.1 ppc ppc AGC46506.1 AGC46506.1 AGC46656.1 AGC46656.1 serC serC AGC46790.1 AGC46790.1 prs prs rpiA rpiA gpmA gpmA AGC47437.1 AGC47437.1 AGC47493.1 AGC47493.1 AGC47539.1 AGC47539.1 deoC deoC tal tal AGC47935.1 AGC47935.1 AGC47936.1 AGC47936.1 tal-2 tal-2 AGC48106.1 AGC48106.1 AGC48189.1 AGC48189.1 AGC48191.1 AGC48191.1 AGC48230.1 AGC48230.1 AGC48248.1 AGC48248.1 pfkA-2 pfkA-2 fumC fumC AGC48390.1 AGC48390.1 AGC48392.1 AGC48392.1 pgi pgi AGC49021.1 AGC49021.1 AGC49049.1 AGC49049.1 AGC49281.1 AGC49281.1
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AGC41395.1Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (364 aa)
AGC41404.1Glucose 1-dehydrogenase. (362 aa)
AGC41633.1Mercuric reductase, truncated. (463 aa)
AGC41788.1Citrate synthase. (410 aa)
AGC41934.1Aldehyde dehydrogenase. (470 aa)
AGC41971.1Thermosensitive gluconokinase. (161 aa)
AGC42145.1Aldehyde dehydrogenase. (524 aa)
AGC42348.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (478 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (223 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (513 aa)
AGC42435.1Glucokinase. (341 aa)
AGC42463.1Succinate dehydrogenase cytochrome b558 subunit. (224 aa)
gpmIPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (513 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (597 aa)
AGC42717.1Transketolase. (345 aa)
AGC42718.1Transketolase. (269 aa)
AGC42731.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (909 aa)
AGC43572.1NUDIX hydrolase. (188 aa)
AGC43873.12-aminomuconic semialdehyde dehydrogenase. (538 aa)
AGC44003.1(S)-2-hydroxy-acid oxidase. (407 aa)
AGC44077.16-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (312 aa)
AGC44279.1Alpha-ribazole-5'-phosphate phosphatase; Belongs to the phosphoglycerate mutase family. (209 aa)
AGC44379.1NUDIX family hydrolase. (226 aa)
pdhAPyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (379 aa)
AGC44384.1Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa)
AGC44385.1Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (532 aa)
AGC44551.1Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (257 aa)
AGC44968.1Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (543 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (321 aa)
AGC45037.1Alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase. (465 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (309 aa)
AGC45039.1Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase. (417 aa)
lipBLipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (361 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (365 aa)
AGC45348.1propionyl-CoA carboxylase subunit alpha; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1167 aa)
AGC45625.1Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase. (580 aa)
AGC45626.1Pyruvate dehydrogenase subunit beta. (325 aa)
AGC45627.1Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase subunit alpha. (344 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)
sucCsuccinyl-CoA synthase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
AGC45727.1Succinate dehydrogenase iron-sulfur subunit. (268 aa)
AGC45728.1Succinate dehydrogenase flavoprotein subunit. (625 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (314 aa)
AGC45730.1Isocitrate dehydrogenase. (432 aa)
AGC45749.1Citrate synthase; Belongs to the citrate synthase family. (433 aa)
AGC45753.1Pyruvate kinase; Belongs to the pyruvate kinase family. (466 aa)
AGC45841.1Hypothetical protein. (345 aa)
AGC46079.1Phosphoenolpyruvate synthase. (289 aa)
AGC46093.1Phosphoenolpyruvate synthase. (553 aa)
AGC46228.1Fructose 1,6-bisphosphatase II. (322 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
AGC46307.12-oxoisovalerate dehydrogenase complex, E1 component subunit alpha. (335 aa)
AGC46308.12-oxoisovalerate dehydrogenase complex, E1 component subunit beta. (352 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (890 aa)
AGC46506.1Ribose 5-phosphate isomerase B. (147 aa)
AGC46656.1Phosphoglucomutase. (545 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa)
AGC46790.12-oxo acid dehydrogenase acyltransferase catalytic subunit. (275 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa)
rpiARibose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (237 aa)
gpmA2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (202 aa)
AGC47437.1Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. (372 aa)
AGC47493.1Alcohol dehydrogenase. (394 aa)
AGC47539.13-oxoacyl-ACP reductase. (267 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (279 aa)
talPutative translaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (216 aa)
AGC47935.12-oxoglutarate dehydrogenase E1 component. (960 aa)
AGC47936.12-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (404 aa)
tal-2Transaldolase family protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (373 aa)
AGC48106.1Transketolase. (633 aa)
AGC48189.1Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (218 aa)
AGC48191.1Pyruvate kinase; Belongs to the pyruvate kinase family. (459 aa)
AGC48230.1Putative isocitrate dehydrogenase, NAD-dependent. (334 aa)
AGC48248.1D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (417 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (345 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
AGC48390.1Glucokinase. (310 aa)
AGC48392.1Phosphomannomutase/phosphoglucomutase. (456 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (529 aa)
AGC49021.1Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (298 aa)
AGC49049.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (337 aa)
AGC49281.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (685 aa)
Your Current Organism:
Myxococcus stipitatus
NCBI taxonomy Id: 1278073
Other names: M. stipitatus DSM 14675, Myxococcus stipitatus DSM 14675
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