STRINGSTRING
queE queE AGC42755.1 AGC42755.1 AGC44727.1 AGC44727.1 AGC45053.1 AGC45053.1 tgt-2 tgt-2 queA queA AGC46437.1 AGC46437.1 AGC46438.1 AGC46438.1 AGC46439.1 AGC46439.1 AGC46440.1 AGC46440.1 AGC46803.1 AGC46803.1 AGC46805.1 AGC46805.1 queF queF queC queC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
queERadical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (230 aa)
AGC42755.1Alkaline phosphatase. (717 aa)
AGC44727.1GTP cyclohydrolase I. (210 aa)
AGC45053.1Alkaline phosphatase. (515 aa)
tgt-2Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (401 aa)
queAS-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (370 aa)
AGC46437.1SpoIID/LytB domain-containing protein. (370 aa)
AGC46438.1Hypothetical protein. (191 aa)
AGC46439.1Hypothetical protein. (113 aa)
AGC46440.1Hypothetical protein. (250 aa)
AGC46803.1Folate biosynthesis protein. (164 aa)
AGC46805.16-pyruvoyl tetrahydrobiopterin synthase. (135 aa)
queFGTP cyclohydrolase family protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (130 aa)
queCexsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (232 aa)
Your Current Organism:
Myxococcus stipitatus
NCBI taxonomy Id: 1278073
Other names: M. stipitatus DSM 14675, Myxococcus stipitatus DSM 14675
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