STRINGSTRING
FFUJ_02913 FFUJ_02913 FFUJ_03641 FFUJ_03641 FSR1 FSR1 PKS-NRPS1 PKS-NRPS1 FFUJ_12074 FFUJ_12074 FFUJ_10900 FFUJ_10900 FUS1 FUS1 FFUJ_12707 FFUJ_12707 FFUJ_14695 FFUJ_14695 FFUJ_14588 FFUJ_14588 FFUJ_06720 FFUJ_06720 FFUJ_03506 FFUJ_03506 FUB8 FUB8 FFUJ_00282 FFUJ_00282 FFUJ_00126 FFUJ_00126
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FFUJ_02913Probable alpha-aminoadipate reductase large subunit. (1167 aa)
FFUJ_03641AM-toxin synthetase (AMT). (1226 aa)
FSR1Non-reducing polyketide synthase fsr1; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of fusarubins, highly pigmented naphthoquinones responsible for the coloration of the fruiting bodies. The non-reducing polyketide synthase FSR1 is responsible for the condensation of seven acetyl-CoA units to yield a haptaketide. After rings A and B are formed by aldol-type cyclization, the PKS-derived product is released as 6-O-demethylfusarubinaldehyde. Then, two hydroxyl groups at C-5 and C-10 are incorporated by FSR3, and simultaneously hydroxyl groups a [...] (2286 aa)
PKS-NRPS1Trichosetin synthetase PKS-NRPS1; Hybrid PKS-NRPS synthetase; part of the gene cluster that mediates the biosynthesis of trichosetin, a trans-fused decalin- containing tetramic acid with antimicrobial activity. The PKS module of PKS-NRPS1 together with the enoylreductase (ER) catalyze the formation of the polyketide unit which is then conjugated to L-serine by the condensation domain of the PKS-NRPS1 NRPS module (By similarity). Activity of the Dieckmann cyclase domain (RED) results in release of the intermediate N-desmethylequisetin also called trichosetin (By similarity). Diels-Alder [...] (3914 aa)
FFUJ_12074Polyketide synthase. (2248 aa)
FFUJ_10900Related to nonribosomal peptide synthetase MxcG. (1085 aa)
FUS1Fusarin C synthetase; Fusarin C synthetase; part of the gene cluster that mediates the biosynthesis of the mycotoxin fusarin C. Within the cluster, FUS1, FUS2, FUS8 and FUS9 are sufficient for fusarin production. The roles of the other FUS members are yet undetermined. The fusarin C synthetase FUS1 is responsible for the condensation of one acetyl-coenzyme A (CoA) unit with six malonyl-CoA units and the amide linkage of the arising heptaketide and homoserine, subsequently releasing the first intermediate, prefusarin, as an alcohol with an open ring structure. The cytochrome P450 monoox [...] (3916 aa)
FFUJ_12707Probable polyketide synthase. (3935 aa)
FFUJ_14695Related to polyketide synthase. (4090 aa)
FFUJ_14588Related to nonribosomal peptide synthetase MxcG. (1061 aa)
FFUJ_06720Related to AM-toxin synthetase (AMT). (994 aa)
FFUJ_03506Related to alpha-aminoadipate reductase large subunit. (1284 aa)
FUB8Non-canonical non-ribosomal peptide synthetase FUB8; Non-canonical non-ribosomal peptide synthetase; part of the gene cluster that mediates the biosynthesis of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties. L-aspartate is suggested as fusaric acid amino acid precursor that is activated and further processed to O-acetyl-L-homoserine by cluster enzymes aspartate kinase FUB3 and homoserine O-acetyltransferase FUB5, as well as enzymes of the primary metabolism. The polyketide synthase (PKS) FUB1 generates the triketide tr [...] (1036 aa)
FFUJ_00282Related to nonribosomal peptide synthetase. (1075 aa)
FFUJ_00126Related to nonribosomal peptide synthetase. (1057 aa)
Your Current Organism:
Fusarium fujikuroi
NCBI taxonomy Id: 1279085
Other names: F. fujikuroi IMI 58289, Fusarium fujikuroi IMI 58289, Fusarium fujikuroi IMI58289, Gibberella fujikuroi IMI 58289
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