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bik1 | Bikaverin polyketide synthase bik1; Polyketide synthase; part of the gene cluster that mediates the biosynthesis of bikaverin, a red pigment also considered as a mycotoxin. The first stage is catalyzed by the polyketide synthase bik1, which catalyzes the formation of the intermediate SMA76a also knowm as pre- bikaverin. FAD- dependent monooxygenase bik2 might then be responsible for the oxidation of pre-bikaverin to oxo-pre-bikaverin which is in turn methylated by the O-methyltransferase bik3 to me-oxo-pre-bikaverin. A further cycle of oxydation and methylation by bik2 and bik3 leads t [...] (2036 aa) | ||||
FFUJ_04563 | Probable fatty-acyl-CoA synthase, beta subunit; Belongs to the fungal fatty acid synthetase subunit beta family. (2103 aa) | ||||
FSR1 | Non-reducing polyketide synthase fsr1; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of fusarubins, highly pigmented naphthoquinones responsible for the coloration of the fruiting bodies. The non-reducing polyketide synthase FSR1 is responsible for the condensation of seven acetyl-CoA units to yield a haptaketide. After rings A and B are formed by aldol-type cyclization, the PKS-derived product is released as 6-O-demethylfusarubinaldehyde. Then, two hydroxyl groups at C-5 and C-10 are incorporated by FSR3, and simultaneously hydroxyl groups a [...] (2286 aa) |