STRINGSTRING
gcvT gcvT AII41862.1 AII41862.1 amiF amiF AII41876.1 AII41876.1 AII41922.1 AII41922.1 AII41923.1 AII41923.1 AII41924.1 AII41924.1 AII41925.1 AII41925.1 purU purU gapA gapA AII42059.1 AII42059.1 AII42060.1 AII42060.1 AII42065.1 AII42065.1 AII42147.1 AII42147.1 glmS glmS ackA ackA AII42189.1 AII42189.1 AII42190.1 AII42190.1 AII42202.1 AII42202.1 AII42268.1 AII42268.1 AII42281.1 AII42281.1 AII42371.1 AII42371.1 lipA lipA ppc ppc AII42523.1 AII42523.1 AII42524.1 AII42524.1 AII42535.1 AII42535.1 tal tal AII42801.1 AII42801.1 AII42889.1 AII42889.1 AII42910.1 AII42910.1 zwf zwf AII42972.1 AII42972.1 AII42973.1 AII42973.1 tpiA tpiA lipA-2 lipA-2 AII43231.1 AII43231.1 prs prs glgA glgA acsA acsA AII43380.1 AII43380.1 pgi pgi pgl pgl AII43574.1 AII43574.1 glgC glgC glpX glpX AII43578.1 AII43578.1 AII43617.1 AII43617.1 AII43619.1 AII43619.1 AII43637.1 AII43637.1 AII43873.1 AII43873.1 AII43880.1 AII43880.1 glgB glgB AII43956.1 AII43956.1 AII43961.1 AII43961.1 pdhA pdhA AII44025.1 AII44025.1 mqo mqo AII44165.1 AII44165.1 lipB lipB rpiA rpiA AII44252.1 AII44252.1 AII44253.1 AII44253.1 sdhA sdhA AII44255.1 AII44255.1 AII44256.1 AII44256.1 AII44271.1 AII44271.1 AII44501.1 AII44501.1 AII44634.1 AII44634.1 pgk pgk eno eno fumC fumC gcvP gcvP gcvH gcvH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (368 aa)
AII41862.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (286 aa)
amiFFormamidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. (348 aa)
AII41876.1Formamidase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (409 aa)
AII41922.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (392 aa)
AII41923.1Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aconitase/IPM isomerase family. (860 aa)
AII41924.1Chloride channel protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (482 aa)
AII41925.1Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (537 aa)
purUHypothetical protein; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (341 aa)
AII42059.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (297 aa)
AII42060.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (280 aa)
AII42065.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the pyruvate kinase family. (353 aa)
AII42147.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (669 aa)
glmSGlutamine amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (630 aa)
ackAHypothetical protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (358 aa)
AII42189.1Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (850 aa)
AII42190.1Phosphoketolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (809 aa)
AII42202.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (474 aa)
AII42268.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (351 aa)
AII42281.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the LDH/MDH superfamily. (355 aa)
AII42371.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1537 aa)
lipARadical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (289 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (1009 aa)
AII42523.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (449 aa)
AII42524.1Trehalose synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (567 aa)
AII42535.1Glycogen-debranching protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the glycosyl hydrolase 13 family. (684 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily. (390 aa)
AII42801.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (254 aa)
AII42889.1Glycoside hydrolase family 57; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the glycosyl hydrolase 57 family. (522 aa)
AII42910.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (78 aa)
zwfGlucose 6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa)
AII42972.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (355 aa)
AII42973.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (357 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (230 aa)
lipA-2Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (299 aa)
AII43231.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (520 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (331 aa)
glgAGlycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (514 aa)
acsA3-hydroxypropionyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (657 aa)
AII43380.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (594 aa)
pgiGlucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the GPI family. (532 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (237 aa)
AII43574.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (472 aa)
glgCGlucose-1-phosphate adenylyltransferase; Catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (431 aa)
glpXType II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FBPase class 2 family. (334 aa)
AII43578.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa)
AII43617.1Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (393 aa)
AII43619.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (473 aa)
AII43637.1Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
AII43873.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial glucokinase family. (360 aa)
AII43880.1Xylose repressor; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (300 aa)
glgBGlycogen branching protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (768 aa)
AII43956.1Ribokinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (275 aa)
AII43961.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the glutaminase family. (554 aa)
pdhAPyruvate dehydrogenase E1 subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (327 aa)
AII44025.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (480 aa)
mqoMalate:quinone oxidoreductase; Malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (522 aa)
AII44165.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (446 aa)
lipBHypothetical protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (237 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (230 aa)
AII44252.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (53 aa)
AII44253.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (214 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (638 aa)
AII44255.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (242 aa)
AII44256.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (169 aa)
AII44271.1Isoamylase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the glycosyl hydrolase 13 family. (692 aa)
AII44501.1Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (552 aa)
AII44634.1Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (396 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the phosphoglycerate kinase family. (402 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
fumCHypothetical protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (470 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (958 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
Your Current Organism:
Synechococcus sp. KORDI100
NCBI taxonomy Id: 1280380
Other names: S. sp. KORDI-100, Synechococcus sp. KORDI-100
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