STRINGSTRING
rplK rplK mrnC mrnC mcsB mcsB pdxS pdxS folK folK AKC77139.1 AKC77139.1 rplY rplY AKC77150.1 AKC77150.1 ispE ispE rnmV rnmV recR recR AKC77169.1 AKC77169.1 AKC77171.1 AKC77171.1 AKC77174.1 AKC77174.1 gltB gltB AKC77192.1 AKC77192.1 yflT yflT AKC77224.1 AKC77224.1 AKC77226.1 AKC77226.1 repA repA AKC77249.1 AKC77249.1 czrB_2 czrB_2 rpsR rpsR rpsF rpsF ychF ychF parB parB rpsB rpsB rpl7AE rpl7AE ribC ribC rpsO rpsO AKC76378.1 AKC76378.1 dnaI_2 dnaI_2 AKC76363.1 AKC76363.1 rpmG_2 rpmG_2 rpsN_2 rpsN_2 sbcD sbcD gyrB_2 gyrB_2 AKC76254.1 AKC76254.1 lysA lysA AKC76244.1 AKC76244.1 AKC76220.1 AKC76220.1 nth nth dnaD dnaD dinG dinG AKC76195.1 AKC76195.1 AKC76186.1 AKC76186.1 rpsA rpsA recQ recQ AKC76162.1 AKC76162.1 rnz rnz bfmBAB_2 bfmBAB_2 acoA_2 acoA_2 recN recN ispA ispA AKC76131.1 AKC76131.1 gluP gluP rpmG_1 rpmG_1 nfo nfo cshB cshB dnaG dnaG dgkA dgkA ybeY ybeY rpsU rpsU rpsT rpsT comEB comEB AKC76069.1 AKC76069.1 nadD nadD AKC76063.1 AKC76063.1 udk udk AKC76048.1 AKC76048.1 nifS nifS rarA rarA AKC76037.1 AKC76037.1 dtd dtd rpmA rpmA rplU rplU radC radC hemA hemA rplT rplT rpmI rpmI dnaI_1 dnaI_1 dnaB dnaB dus dus AKC75969.1 AKC75969.1 AKC75966.1 AKC75966.1 ackA ackA AKC75957.1 AKC75957.1 ezrA ezrA rpsD rpsD AKC75951.1 AKC75951.1 ptaA ptaA fhs fhs acsA acsA acuA acuA AKC75929.1 AKC75929.1 ribA ribA AKC75888.1 AKC75888.1 hemY hemY hemH hemH AKC75866.1 AKC75866.1 bcp bcp AKC75829.1 AKC75829.1 fabG_2 fabG_2 murE2 murE2 AKC75792.1 AKC75792.1 pheA pheA AKC75771.1 AKC75771.1 AKC75753.1 AKC75753.1 AKC75747.1 AKC75747.1 leuA leuA rsbU rsbU cshA cshA rpmE2 rpmE2 hmrA hmrA AKC75652.1 AKC75652.1 czrB_1 czrB_1 cobB cobB rpsI rpsI rplM rplM truA truA rplQ rplQ rpsK rpsK rpsM rpsM rpmJ rpmJ rplO rplO rpmD rpmD rpsE rpsE rplR rplR rplF rplF rpsH rpsH rpsN_1 rpsN_1 rplE rplE rplX rplX rplN rplN rpsQ rpsQ rpmC rpmC rplP rplP rpsC rpsC rplV rplV rpsS rpsS rplB rplB rplW rplW rplD rplD rplC rplC rpsJ rpsJ topB topB caiA caiA murP murP AKC75500.1 AKC75500.1 AKC75495.1 AKC75495.1 hutG hutG fni fni AKC75477.1 AKC75477.1 AKC75454.1 AKC75454.1 AKC75445.1 AKC75445.1 cbiX cbiX AKC75407.1 AKC75407.1 AKC75397.1 AKC75397.1 AKC75379.1 AKC75379.1 gltB2 gltB2 metB_1 metB_1 AKC75322.1 AKC75322.1 aes aes AKC75296.1 AKC75296.1 mvaA mvaA mvaS mvaS ada ada crtN crtN AKC75271.1 AKC75271.1 topA topA rbgA rbgA rplS rplS rpsP rpsP smc smc rpmB rpmB priA priA AKC76515.1 AKC76515.1 trxA trxA AKC76546.1 AKC76546.1 rpmF rpmF ctaA ctaA typA typA AKC76583.1 AKC76583.1 pdhB pdhB pdhA pdhA AKC76589.1 AKC76589.1 AKC76598.1 AKC76598.1 AKC76602.1 AKC76602.1 purD purD purF purF AKC76631.1 AKC76631.1 menF menF mgtE mgtE fabB fabB mhpD mhpD AKC76714.1 AKC76714.1 sufB sufB sufD sufD sufC sufC AKC76762.1 AKC76762.1 AKC76804.1 AKC76804.1 AKC76828.1 AKC76828.1 yfiA yfiA AKC76874.1 AKC76874.1 AKC76878.1 AKC76878.1 queD queD graS graS AKC76940.1 AKC76940.1 argE_3 argE_3 AKC76982.1 AKC76982.1 AKC77006.1 AKC77006.1 AKC77037.1 AKC77037.1 tadA tadA AKC77076.1 AKC77076.1 AKC77077.1 AKC77077.1 AKC77079.1 AKC77079.1 capD capD AKC77090.1 AKC77090.1 AKC77094.1 AKC77094.1 crtI crtI AKC75236.1 AKC75236.1 acsA2 acsA2 AKC75221.1 AKC75221.1 AKC75219.1 AKC75219.1 sat sat nsaS nsaS phoA phoA cap5N cap5N AKC75155.1 AKC75155.1 bioB bioB AKC75066.1 AKC75066.1 AKC75049.1 AKC75049.1 bfmBAB_1 bfmBAB_1 acoA_1 acoA_1 AKC75019.1 AKC75019.1 AKC75018.1 AKC75018.1 AKC74973.1 AKC74973.1 AKC74970.1 AKC74970.1 argE_1 argE_1 yycJ yycJ dnaC dnaC gyrB_1 gyrB_1 recF recF rpsG rpsG noc noc rpsL rpsL rplL rplL rplJ rplJ rplA rplA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rplK50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (140 aa)
mrnCRibonuclease III; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (136 aa)
mcsBD-isomer specific 2-hydroxyacid dehydrogenase family protein; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family. (335 aa)
pdxSPyridoxal biosynthesis lyase; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (295 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (159 aa)
AKC77139.1Polyribonucleotide nucleotidyltransferase. (133 aa)
rplY50S ribosomal protein L25 Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (221 aa)
AKC77150.1Endoribonuclease L-PSP. (126 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. (282 aa)
rnmVRibonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. (182 aa)
recRRecombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (198 aa)
AKC77169.1Nucleoid-associated protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (105 aa)
AKC77171.1Acetyltransferase (GNAT) family protein. (192 aa)
AKC77174.1PTS system trehalose-specific IIBC component. (482 aa)
gltBGlutamate synthase (NADPH), large subunit. (1506 aa)
AKC77192.1Patatin-like phospholipase. (285 aa)
yflTHeat induced stress protein. (135 aa)
AKC77224.1IS200-family transposase. (106 aa)
AKC77226.1N-acetyltransferase GCN5. (184 aa)
repAReplication initiator protein A. (318 aa)
AKC77249.1Reverse transcriptase (RNA-dependent DNA polymerase). (296 aa)
czrB_2Cation diffusion facilitator family transporter. (313 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (80 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (98 aa)
ychFGTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (365 aa)
parBChromosome/plasmid partitioning protein ParB; Belongs to the ParB family. (276 aa)
rpsB30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (262 aa)
rpl7AERibosomal protein L7AE family protein. (48 aa)
ribCBifunctional protein including riboflavin kinaseand FAD synthase; Belongs to the ribF family. (323 aa)
rpsO30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
AKC76378.1Phage-related protein. (250 aa)
dnaI_2Primosomal protein. (268 aa)
AKC76363.1Phage HNH endonuclease. (104 aa)
rpmG_250S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)
rpsN_230S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (89 aa)
sbcDDNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (374 aa)
gyrB_2DNA topoisomerase subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. (666 aa)
AKC76254.1Zinc peptidase. (384 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa)
AKC76244.1ATPase. (263 aa)
AKC76220.1Cell wall enzyme EbsB-like protein. (133 aa)
nthDNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (219 aa)
dnaDDNA replication protein, DnaD. (228 aa)
dinGDNA polymerase III, epsilon subunit/ATP-dependent helicase DinG; 3'-5' exonuclease. (900 aa)
AKC76195.1PEP-CTERM system TPR-repeat lipoprotein. (414 aa)
AKC76186.1Histone family protein DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
rpsA30S ribosomal protein S1. (392 aa)
recQATP-dependent DNA helicase. (459 aa)
AKC76162.1Short chain dehydrogenase. (251 aa)
rnzMetallo-beta-lactamase, AtsA/ElaC family; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (306 aa)
bfmBAB_22-oxoisovalerate dehydrogenase, E1 component, beta subunit. (327 aa)
acoA_22-oxoisovalerate dehydrogenase subunit alpha. (333 aa)
recNDNA repair protein; May be involved in recombinational repair of damaged DNA. (561 aa)
ispAGeranyltranstransferase; Belongs to the FPP/GGPP synthase family. (248 aa)
AKC76131.1Hypothetical protein. (71 aa)
gluPPeptidase, rhomboid family protein. (485 aa)
rpmG_150S ribosomal protein L33 type 1; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)
nfoDeoxyribonuclease IV (phage-T(4)-induced); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (296 aa)
cshBATP-dependent RNA helicase DEAD/DEAH box family protein; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. (448 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (601 aa)
dgkADiacylglycerol kinase. (72 aa)
ybeYMetalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (153 aa)
rpsU30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (58 aa)
rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (83 aa)
comEBLate competence operon required for DNA binding and uptake comEB. (152 aa)
AKC76069.1Methyltransferase. (241 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (192 aa)
AKC76063.1GTPase family protein. (366 aa)
udkUridine kinase. (207 aa)
AKC76048.1Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (142 aa)
nifSCysteine desulfurase, NifS. (379 aa)
rarADNA-directed DNA polymerase III subunit gamma and tau. (422 aa)
AKC76037.1ThiF family protein. (258 aa)
dtdD-tyrosyl-tRNA (Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (150 aa)
rpmA50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (94 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa)
radCDNA repair protein RadC; Belongs to the UPF0758 family. (223 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (448 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
rpmI50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (66 aa)
dnaI_1Primosomal protein. (306 aa)
dnaBChromosome replication initiation and membrane attachment protein. (461 aa)
dustRNA dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (325 aa)
AKC75969.1Exopolyphosphatase-like protein. (312 aa)
AKC75966.1Metal-dependent hydrolase; Belongs to the UPF0173 family. (229 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (386 aa)
AKC75957.1Cysteine desulfurase. (342 aa)
ezrASeptation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (564 aa)
rpsD30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (200 aa)
AKC75951.1Soluble hydrogenase subunit. (386 aa)
ptaAPhosphotransferase system, N-acetylglucosamine-specific IIBC component. (487 aa)
fhsFormyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. (555 aa)
acsAAcetyl-coenzyme A synthetase. (569 aa)
acuAAcetoin dehydrogenase-like protein. (210 aa)
AKC75929.1Thioredoxin family protein. (103 aa)
ribABifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (393 aa)
AKC75888.1Hypothetical protein. (302 aa)
hemYProtoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (464 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (307 aa)
AKC75866.1Calcineurin-like phosphoesterase. (398 aa)
bcpAlkyl hydroperoxide reductase. (151 aa)
AKC75829.1acyl-CoA thioester hydrolase. (177 aa)
fabG_23-oxoacyl-ACP reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
murE2UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase. (436 aa)
AKC75792.1Nitric-oxide synthase, oxygenase subunit; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily. (355 aa)
pheAPrephenate dehydratase. (266 aa)
AKC75771.1Hypothetical protein. (132 aa)
AKC75753.1Nitroreductase family protein. (207 aa)
AKC75747.1Fructokinase. (321 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (510 aa)
rsbUSigma factor sigB regulation protein. (333 aa)
cshAATP-dependent RNA helicase DEAD box family protein; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. (503 aa)
rpmE250S ribosomal protein L31. (85 aa)
hmrAPeptidase, M20/M25/M40 family; Belongs to the peptidase M20A family. (394 aa)
AKC75652.1Thiol-disulfide oxidoreductase, DCC family. (131 aa)
czrB_1Cation diffusion facilitator family transporter. (316 aa)
cobBNAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (243 aa)
rpsI30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (130 aa)
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (145 aa)
truAtRNA pseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (267 aa)
rplQ50S ribosomal protein L17. (123 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (121 aa)
rpmJ50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (37 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (146 aa)
rpmD50S ribosomal protein L30. (59 aa)
rpsE30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (166 aa)
rplR50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (120 aa)
rplF50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
rpsH30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rpsN_130S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rplX50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (105 aa)
rplN50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (87 aa)
rpmC50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (69 aa)
rplP50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (144 aa)
rpsC30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (217 aa)
rplV50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (117 aa)
rpsS30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (277 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (91 aa)
rplD50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (207 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (220 aa)
rpsJ30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
topBDNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] (711 aa)
caiAacyl-CoA dehydrogenase. (381 aa)
murPN-acetylmuramic acid phosphotransfer permease. (477 aa)
AKC75500.1PTS system glucose-specific IIBC component. (533 aa)
AKC75495.1Amino acid amidohydrolase. (377 aa)
hutGFormiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (311 aa)
fniIsopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (349 aa)
AKC75477.1Alpha/beta hydrolase fold-3 domain-containing protein. (299 aa)
AKC75454.1Acetyltransferase (GNAT) family protein. (133 aa)
AKC75445.1PTS system sucrose-specific IIBC component. (480 aa)
cbiXSirohydrochlorin cobalt chelatase. (238 aa)
AKC75407.1Cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (288 aa)
AKC75397.1Calcineurin-like phosphoesterase. (272 aa)
AKC75379.1Hypothetical protein. (199 aa)
gltB2Glutamate synthase-ferredoxin large subunit; Belongs to the glutamate synthase family. (526 aa)
metB_1Bifunctional cystathionine gamma-lyase/gamma-synthase. (428 aa)
AKC75322.1GNAT family acetyltransferase. (93 aa)
aesAlpha/beta hydrolase fold-3 domain-containing protein. (323 aa)
AKC75296.1PTS system, glucose-specific IICBA component. (675 aa)
mvaAhydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family. (425 aa)
mvaS3-hydroxy-3-methylglutaryl coenzyme A synthase. (388 aa)
adamethylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (173 aa)
crtNDehydrosqualene desaturase. (463 aa)
AKC75271.1Squalene/phytoene synthase. (285 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (689 aa)
rbgAGTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (294 aa)
rplS50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (116 aa)
rpsP30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (91 aa)
smcSMC superfamily ATP-binding chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1189 aa)
rpmB50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (62 aa)
priAPrimosomal protein N prime; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (802 aa)
AKC76515.1S4 RNA binding domain protein. (275 aa)
trxAThioredoxin; Belongs to the thioredoxin family. (71 aa)
AKC76546.1Bifunctional DNA polymerase / phosphoesterase. (570 aa)
rpmF50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (57 aa)
ctaACytochrome oxidase assembly protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily. (310 aa)
typASmall GTP-binding protein domain:GTP-binding protein TypA. (614 aa)
AKC76583.1Transcriptional regulator Cro/CI family protein. (179 aa)
pdhBPyruvate dehydrogenase E1 component subunit beta. (325 aa)
pdhAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (370 aa)
AKC76589.1Cell-wall binding lipoprotein, YkyA. (207 aa)
AKC76598.1IS200-family transposase. (106 aa)
AKC76602.1Hypothetical protein. (180 aa)
purDPhosphoribosylamine--glycine ligase PurD; Belongs to the GARS family. (414 aa)
purFAmidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (494 aa)
AKC76631.1GNAT family acetyltransferase. (140 aa)
menFSalicylate biosynthesis isochorismate synthase. (455 aa)
mgtEMgtE family magnesium (Mg2+)/cobalt (Co2+) transporter-E; Acts as a magnesium transporter. (461 aa)
fabB3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (414 aa)
mhpD2-keto-4-pentenoate hydratase. (301 aa)
AKC76714.1S1 RNA-binding domain protein. (126 aa)
sufBABC superfamily ATP binding cassette transporter, membrane protein. (465 aa)
sufDABC superfamily ATP binding cassette transporter, membrane protein. (435 aa)
sufCABC superfamily ATP binding cassette transporter, ABC protein. (253 aa)
AKC76762.1Small primase-like protein (Toprim domain). (128 aa)
AKC76804.1Hypothetical protein. (537 aa)
AKC76828.1NAD dependent epimerase/dehydratase familyprotein. (299 aa)
yfiASigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (192 aa)
AKC76874.15'(3')-deoxyribonucleotidase. (177 aa)
AKC76878.1ATP-dependent DNA helicase. (592 aa)
queD6-pyruvoyl-tetrahydropterin synthase. (139 aa)
graSSensor histidine kinase, GraS. (344 aa)
AKC76940.1Alpha/beta hydrolase. (348 aa)
argE_3Succinyl-diaminopimelate desuccinylase. (413 aa)
AKC76982.1HlyD family secretion protein. (308 aa)
AKC77006.1Phosphotransferase enzyme family protein. (299 aa)
AKC77037.1Metal-dependent phosphohydrolase. (432 aa)
tadAtRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (157 aa)
AKC77076.1Deoxynucleoside kinase. (205 aa)
AKC77077.1Deoxynucleoside kinase. (220 aa)
AKC77079.1Acetyltransferase (GNAT) family protein. (139 aa)
capDNAD dependent epimerase/dehydratase family protein. (318 aa)
AKC77090.1Ornithine cyclodeaminase. (319 aa)
AKC77094.1N-acyl-L-amino acid amidohydrolase. (391 aa)
crtIPhytoene desaturase. (502 aa)
AKC75236.1Topology modulation protein. (122 aa)
acsA2AMP-dependent synthetase and ligase. (531 aa)
AKC75221.1Peptidase, M20/M25/M40 family. (393 aa)
AKC75219.1Peptidase, M20/M25/M40 family. (391 aa)
satSulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family. (392 aa)
nsaSIntegral membrane sensor signal transduction histidine kinase. (298 aa)
phoAAlkaline phosphatase PhoA; Belongs to the alkaline phosphatase family. (491 aa)
cap5NCapsular polysaccharide biosynthesis protein Cap5N. (287 aa)
AKC75155.1PTS system maltose/glucose-specific IICB component. (512 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (321 aa)
AKC75066.1Hypothetical protein. (257 aa)
AKC75049.1Hypothetical protein. (492 aa)
bfmBAB_12-oxoisovalerate dehydrogenase, E1 component, beta subunit. (346 aa)
acoA_12-oxoisovalerate dehydrogenase subunit alpha. (315 aa)
AKC75019.13-beta hydroxysteroid dehydrogenase/isomerase. (272 aa)
AKC75018.13-beta hydroxysteroid dehydrogenase/isomerase. (53 aa)
AKC74973.16-pyruvoyl tetrahydropterin synthase. (143 aa)
AKC74970.1Patatin-like phospholipase. (286 aa)
argE_1Succinyl-diaminopimelate desuccinylase. (407 aa)
yycJMetallo-beta-lactamase hydrolase. (266 aa)
dnaCReplicative DNA helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (466 aa)
gyrB_1DNA topoisomerase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (644 aa)
recFDNA repair and genetic recombination protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (371 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
nocParB family nucleoid occlusion protein, Noc; Belongs to the ParB family. (279 aa)
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (137 aa)
rplL50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (122 aa)
rplJ50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (166 aa)
rplA50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (231 aa)
Your Current Organism:
Staphylococcus haemolyticus
NCBI taxonomy Id: 1283
Other names: ATCC 29970, CCM 2737, CCUG 7323, CIP 81.56, DSM 20263, JCM 2416, LMG 13349, LMG:13349, NCTC 11042, NRRL B-14755, S. haemolyticus
Server load: very high (>100%) [HD]