(22 nodes) Mixed, incl. TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition), and Domain in receptor targeting proteins Lin-2 and Lin-7 network (Nipponia nippon)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PARD3	Partitioning defective 3. (1236 aa)
	PRKCI	Protein kinase C iota type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (562 aa)
	CRB2	Fibropellin-1. (576 aa)
	PRKCZ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
	LNX2	Ligand of Numb protein X 2. (687 aa)
	Y956_07562	Partitioning defective 3 B. (57 aa)
	MPP3	MAGUK p55 subfamily member 3. (561 aa)
	Y956_07559	Partitioning defective 3 B. (98 aa)
	Y956_07560	Partitioning defective 3 B. (148 aa)
	Y956_07558	Partitioning defective 3 B. (124 aa)
	ANKRD33	Ankyrin repeat domain-containing protein 33. (336 aa)
	PARD6B	Partitioning defective 6 beta. (347 aa)
	MPDZ	Multiple PDZ domain protein. (2002 aa)
	MPP7	MAGUK p55 subfamily member 7. (564 aa)
	PARD6A	Partitioning defective 6 beta. (288 aa)
	Y956_12188	Ligand of Numb protein X 2. (651 aa)
	PARD6G	Partitioning defective 6 gamma. (282 aa)
	MPP5	MAGUK p55 subfamily member 5; Belongs to the MAGUK family. (675 aa)
	Y956_12103	Lethal(2) giant larvae protein 2. (712 aa)
	CRB1	Protein crumbs 1. (1388 aa)
	PARD3B	Partitioning defective 3 B. (281 aa)
	Y956_08126	E3 ubiquitin-protein ligase LNX. (667 aa)

Your Current Organism:

Nipponia nippon

NCBI taxonomy Id: 128390
Other names: Ibis nippon, N. nippon, crested ibis

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD33	LNX2	A0A091V248	A0A091USC1	Ankyrin repeat domain-containing protein 33.	Ligand of Numb protein X 2.	0.418
ANKRD33	MPDZ	A0A091V248	A0A091V5H5	Ankyrin repeat domain-containing protein 33.	Multiple PDZ domain protein.	0.418
ANKRD33	Y956_08126	A0A091V248	A0A091X2T9	Ankyrin repeat domain-containing protein 33.	E3 ubiquitin-protein ligase LNX.	0.418
ANKRD33	Y956_12188	A0A091V248	A0A091VM87	Ankyrin repeat domain-containing protein 33.	Ligand of Numb protein X 2.	0.418
CRB1	MPDZ	A0A091VZ24	A0A091V5H5	Protein crumbs 1.	Multiple PDZ domain protein.	0.547
CRB1	MPP5	A0A091VZ24	A0A091VUW2	Protein crumbs 1.	MAGUK p55 subfamily member 5; Belongs to the MAGUK family.	0.923
CRB1	Y956_12103	A0A091VZ24	A0A091VX31	Protein crumbs 1.	Lethal(2) giant larvae protein 2.	0.431
CRB2	MPP5	A0A091UQT3	A0A091VUW2	Fibropellin-1.	MAGUK p55 subfamily member 5; Belongs to the MAGUK family.	0.806
LNX2	ANKRD33	A0A091USC1	A0A091V248	Ligand of Numb protein X 2.	Ankyrin repeat domain-containing protein 33.	0.418
LNX2	MPP3	A0A091USC1	A0A091UVV9	Ligand of Numb protein X 2.	MAGUK p55 subfamily member 3.	0.490
LNX2	MPP5	A0A091USC1	A0A091VUW2	Ligand of Numb protein X 2.	MAGUK p55 subfamily member 5; Belongs to the MAGUK family.	0.490
LNX2	MPP7	A0A091USC1	A0A091VG58	Ligand of Numb protein X 2.	MAGUK p55 subfamily member 7.	0.490
LNX2	PRKCI	A0A091USC1	A0A091UPZ8	Ligand of Numb protein X 2.	Protein kinase C iota type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.471
LNX2	PRKCZ	A0A091USC1	A0A091US24	Ligand of Numb protein X 2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.471
MPDZ	ANKRD33	A0A091V5H5	A0A091V248	Multiple PDZ domain protein.	Ankyrin repeat domain-containing protein 33.	0.418
MPDZ	CRB1	A0A091V5H5	A0A091VZ24	Multiple PDZ domain protein.	Protein crumbs 1.	0.547
MPDZ	MPP3	A0A091V5H5	A0A091UVV9	Multiple PDZ domain protein.	MAGUK p55 subfamily member 3.	0.490
MPDZ	MPP5	A0A091V5H5	A0A091VUW2	Multiple PDZ domain protein.	MAGUK p55 subfamily member 5; Belongs to the MAGUK family.	0.988
MPDZ	MPP7	A0A091V5H5	A0A091VG58	Multiple PDZ domain protein.	MAGUK p55 subfamily member 7.	0.490
MPDZ	PARD6A	A0A091V5H5	A0A091VIN7	Multiple PDZ domain protein.	Partitioning defective 6 beta.	0.484