STRINGSTRING
MED17 MED17 SRF SRF ERCC6 ERCC6 MED1 MED1 MED13 MED13 TBP TBP GTF2A1 GTF2A1 TAF3 TAF3 MED4 MED4 Y956_10782 Y956_10782 MED14 MED14 TAF8 TAF8 Y956_15257 Y956_15257 Y956_02628 Y956_02628 TPP1 TPP1 Y956_06881 Y956_06881 MED16 MED16 MED30 MED30 HNF1B HNF1B Y956_14641 Y956_14641 DHX36 DHX36 MED24 MED24 TAF13 TAF13 GTF2A2 GTF2A2 TAF12 TAF12 TAF4B TAF4B NKX2-5 NKX2-5 Y956_14642 Y956_14642 PSMC6 PSMC6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (566 aa)
SRFMADS-box domain-containing protein. (338 aa)
ERCC6DNA excision repair protein ERCC-6. (1506 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1574 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2179 aa)
TBPTATA-box-binding protein. (299 aa)
GTF2A1Transcription initiation factor IIA subunit 1. (357 aa)
TAF3Transcription initiation factor TFIID subunit 3. (917 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (229 aa)
Y956_10782Activated RNA polymerase II transcriptional coactivator p15. (135 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1378 aa)
TAF8Transcription initiation factor TFIID subunit 8. (290 aa)
Y956_15257Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (512 aa)
Y956_02628Transcription initiation factor TFIID subunit 4. (259 aa)
TPP1Transcription initiation factor TFIID subunit 10. (134 aa)
Y956_06881Activated RNA polymerase II transcriptional coactivator p15. (130 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (869 aa)
MED30Mediator of RNA polymerase II transcription subunit 30. (179 aa)
HNF1BHepatocyte nuclear factor 1-beta. (551 aa)
Y956_14641Glutamine-rich protein 2. (146 aa)
DHX36Putative ATP-dependent RNA helicase DHX36. (910 aa)
MED24Mediator of RNA polymerase II transcription subunit 24. (945 aa)
TAF13Transcription initiation factor TFIID subunit 13. (115 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
TAF12Transcription initiation factor TFIID subunit 12. (161 aa)
TAF4BTranscription initiation factor TFIID subunit 4B. (587 aa)
NKX2-5Homeobox protein Nkx-2.5. (299 aa)
Y956_14642Glutamine-rich protein 2. (142 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (361 aa)
Your Current Organism:
Nipponia nippon
NCBI taxonomy Id: 128390
Other names: Ibis nippon, N. nippon, crested ibis
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