(41 nodes) Toll Like Receptor 7/8 (TLR7/8) Cascade network (Dactylellina haptotyla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H072_9788	Uncharacterized protein. (285 aa)
	H072_10617	Uncharacterized protein. (403 aa)
	H072_11098	APH domain-containing protein. (226 aa)
	H072_303	BZIP domain-containing protein. (323 aa)
	H072_1735	Uncharacterized protein. (617 aa)
	H072_306	CIA30 domain-containing protein. (304 aa)
	H072_125	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (351 aa)
	H072_676	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (350 aa)
	H072_675	Uncharacterized protein. (734 aa)
	H072_1130	Ubiquitin-like domain-containing protein. (480 aa)
	H072_1333	BZIP domain-containing protein. (591 aa)
	H072_3202	BZIP domain-containing protein. (550 aa)
	H072_6044	Uncharacterized protein. (709 aa)
	H072_4648	Uncharacterized protein. (344 aa)
	H072_88	Uncharacterized protein. (578 aa)
	H072_1583	Ubiquitin-like domain-containing protein. (456 aa)
	H072_3225	Uncharacterized protein. (188 aa)
	H072_1508	Uncharacterized protein. (207 aa)
	H072_3553	BZIP domain-containing protein. (490 aa)
	H072_4837	Protein kinase domain-containing protein. (635 aa)
	H072_3863	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (161 aa)
	H072_4094	Uncharacterized protein. (229 aa)
	H072_5311	Uncharacterized protein. (94 aa)
	H072_6442	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (384 aa)
	H072_4835	APH domain-containing protein. (198 aa)
	H072_8496	Uncharacterized protein. (489 aa)
	H072_6607	Uncharacterized protein. (966 aa)
	H072_7853	Uncharacterized protein. (250 aa)
	H072_10237	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (415 aa)
	H072_10303	Ubiquitin-like domain-containing protein. (561 aa)
	H072_8834	F-box domain-containing protein. (367 aa)
	H072_10672	Ubiquitin-like domain-containing protein. (152 aa)
	H072_556	Uncharacterized protein. (467 aa)
	H072_3222	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (486 aa)
	H072_10850	TYR_PHOSPHATASE_2 domain-containing protein. (314 aa)
	H072_6420	Uncharacterized protein. (299 aa)
	H072_206	Uncharacterized protein. (902 aa)
	H072_6008	Serine/threonine-protein phosphatase. (324 aa)
	H072_6357	Uncharacterized protein. (520 aa)
	H072_11260	Uncharacterized protein. (653 aa)
	H072_6824	APH domain-containing protein. (409 aa)

Your Current Organism:

Dactylellina haptotyla

NCBI taxonomy Id: 1284197
Other names: D. haptotyla CBS 200.50, Dactylellina haptotyla CBS 200.50, Monacrosporium haptotylum CBS 200.50

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H072_10237	H072_10303	S8A502	S8A4Z0	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Ubiquitin-like domain-containing protein.	0.450
H072_10237	H072_10672	S8A502	S7ZYS1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Ubiquitin-like domain-containing protein.	0.450
H072_10237	H072_11098	S8A502	S8B8Y7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	APH domain-containing protein.	0.447
H072_10237	H072_11260	S8A502	S8BJK6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.582
H072_10237	H072_1130	S8A502	S8APW6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Ubiquitin-like domain-containing protein.	0.450
H072_10237	H072_125	S8A502	S8ASE6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.683
H072_10237	H072_1333	S8A502	S8APA0	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	BZIP domain-containing protein.	0.819
H072_10237	H072_1508	S8A502	S8ANG1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.782
H072_10237	H072_1583	S8A502	S8C9T7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Ubiquitin-like domain-containing protein.	0.450
H072_10237	H072_1735	S8A502	S8ATK6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.606
H072_10237	H072_206	S8A502	S8CDE8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.685
H072_10237	H072_303	S8A502	S8AXN3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	BZIP domain-containing protein.	0.450
H072_10237	H072_306	S8A502	S8ASM8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	CIA30 domain-containing protein.	0.450
H072_10237	H072_3202	S8A502	S8AP85	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	BZIP domain-containing protein.	0.747
H072_10237	H072_3222	S8A502	S8BTS9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.980
H072_10237	H072_3225	S8A502	S8ANX9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.685
H072_10237	H072_3553	S8A502	S8AMV2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	BZIP domain-containing protein.	0.801
H072_10237	H072_3863	S8A502	S8AH34	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.685
H072_10237	H072_4094	S8A502	S8AFX1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.549
H072_10237	H072_4648	S8A502	S8C1M4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.685