(5 nodes) Band 7 domain, and Protein catabolic process network (Neorickettsia helminthoeca)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

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gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	hflK	hflK protein; HflC and HflK could encode or regulate a protease. (346 aa)
	hflC	hflC protein; HflC and HflK could regulate a protease. (287 aa)
	NHE_0150	Trypsin family protein. (474 aa)
	lon	ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (821 aa)
	hflB	ATP-dependent metallopeptidase HflB family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (641 aa)

Your Current Organism:

Neorickettsia helminthoeca

NCBI taxonomy Id: 1286528
Other names: N. helminthoeca str. Oregon, Neorickettsia helminthoeca str. Oregon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NHE_0150	hflB	NHE_0150	NHE_0401	Trypsin family protein.	ATP-dependent metallopeptidase HflB family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.581
NHE_0150	hflC	NHE_0150	NHE_0149	Trypsin family protein.	hflC protein; HflC and HflK could regulate a protease.	0.850
NHE_0150	hflK	NHE_0150	NHE_0148	Trypsin family protein.	hflK protein; HflC and HflK could encode or regulate a protease.	0.851
NHE_0150	lon	NHE_0150	NHE_0336	Trypsin family protein.	ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.	0.863
hflB	NHE_0150	NHE_0401	NHE_0150	ATP-dependent metallopeptidase HflB family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	Trypsin family protein.	0.581
hflB	hflC	NHE_0401	NHE_0149	ATP-dependent metallopeptidase HflB family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	hflC protein; HflC and HflK could regulate a protease.	0.997
hflB	hflK	NHE_0401	NHE_0148	ATP-dependent metallopeptidase HflB family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	hflK protein; HflC and HflK could encode or regulate a protease.	0.997
hflB	lon	NHE_0401	NHE_0336	ATP-dependent metallopeptidase HflB family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.	0.769
hflC	NHE_0150	NHE_0149	NHE_0150	hflC protein; HflC and HflK could regulate a protease.	Trypsin family protein.	0.850
hflC	hflB	NHE_0149	NHE_0401	hflC protein; HflC and HflK could regulate a protease.	ATP-dependent metallopeptidase HflB family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.997
hflC	hflK	NHE_0149	NHE_0148	hflC protein; HflC and HflK could regulate a protease.	hflK protein; HflC and HflK could encode or regulate a protease.	0.999
hflK	NHE_0150	NHE_0148	NHE_0150	hflK protein; HflC and HflK could encode or regulate a protease.	Trypsin family protein.	0.851
hflK	hflB	NHE_0148	NHE_0401	hflK protein; HflC and HflK could encode or regulate a protease.	ATP-dependent metallopeptidase HflB family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.997
hflK	hflC	NHE_0148	NHE_0149	hflK protein; HflC and HflK could encode or regulate a protease.	hflC protein; HflC and HflK could regulate a protease.	0.999
lon	NHE_0150	NHE_0336	NHE_0150	ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.	Trypsin family protein.	0.863
lon	hflB	NHE_0336	NHE_0401	ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.	ATP-dependent metallopeptidase HflB family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.769