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rplI rplI rpsR rpsR rpsF rpsF rpsP rpsP efp efp rplT rplT rpmG rpmG rpsJ rpsJ rplC rplC NHE_0252 NHE_0252 rplN rplN rplX rplX rplE rplE rpsH rpsH NHE_0264 NHE_0264 NHE_0266 NHE_0266 NHE_0267 NHE_0267 rplQ rplQ rplY rplY NHE_0307 NHE_0307 NHE_0389 NHE_0389 rpmE rpmE NHE_0642 NHE_0642 NHE_0643 NHE_0643 NHE_0644 NHE_0644 rplK rplK tuf tuf fusA fusA rpsL rpsL NHE_0750 NHE_0750 rpsU rpsU rpsI rpsI rplM rplM rplS rplS rpmA rpmA rplU rplU NHE_0887 NHE_0887 rpsB rpsB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rplIRibosomal protein L9; Binds to the 23S rRNA. (161 aa)
rpsRRibosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (83 aa)
rpsFRibosomal protein S6. (106 aa)
rpsPRibosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (81 aa)
efpTranslation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (191 aa)
rplTRibosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (117 aa)
rpmGRibosomal protein L33. (59 aa)
rpsJRibosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (210 aa)
NHE_0252Ribosomal L23 family protein. (96 aa)
rplNRibosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (119 aa)
rplXRibosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (103 aa)
rplERibosomal L5 family protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (177 aa)
rpsHRibosomal S8 family protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (131 aa)
NHE_0264Ribosomal L6 family protein; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. (176 aa)
NHE_0266Ribosomal S5, N-terminal domain protein; Belongs to the universal ribosomal protein uS5 family. (172 aa)
NHE_0267Putative ribosomal protein L15. (82 aa)
rplQRibosomal protein L17. (116 aa)
rplYRibosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (195 aa)
NHE_0307Hypothetical protein. (50 aa)
NHE_0389S1 RNA binding domain protein. (520 aa)
rpmERibosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family. (78 aa)
NHE_0642Ribosomal L7/L12 domain protein. (140 aa)
NHE_0643Ribosomal L10 family protein. (176 aa)
NHE_0644Ribosomal L1p/L10e family protein; Belongs to the universal ribosomal protein uL1 family. (209 aa)
rplKRibosomal L11, N-terminal domain protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (143 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (428 aa)
fusATranslation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (686 aa)
rpsLRibosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (122 aa)
NHE_0750Ribosomal S20 family protein. (53 aa)
rpsURibosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (58 aa)
rpsIRibosomal S9/S16 family protein; Belongs to the universal ribosomal protein uS9 family. (145 aa)
rplMRibosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (152 aa)
rplSRibosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (122 aa)
rpmARibosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (82 aa)
rplURibosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (99 aa)
NHE_0887Ribosomal L36 family protein. (87 aa)
rpsBRibosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (310 aa)
Your Current Organism:
Neorickettsia helminthoeca
NCBI taxonomy Id: 1286528
Other names: N. helminthoeca str. Oregon, Neorickettsia helminthoeca str. Oregon
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