(13 nodes) Translesion synthesis network (Eutypa lata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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Predicted Interactions

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gene fusions

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Your Input:
	UCREL1_10853	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (921 aa)
	UCREL1_6540	Putative dna polymerase iota protein. (885 aa)
	UCREL1_8269	Uncharacterized protein. (317 aa)
	UCREL1_7576	Putative dna polymerase epsilon subunit b protein. (834 aa)
	UCREL1_872	Putative dna polymerase zeta catalytic subunit protein. (698 aa)
	UCREL1_1947	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (319 aa)
	UCREL1_11385	Putative horma domain-containing protein. (263 aa)
	UCREL1_1165	Putative sister chromatid cohesion protein eso1 protein. (283 aa)
	UCREL1_7360	Putative brca1 c terminus domain-containing protein. (362 aa)
	UCREL1_2448	Putative ubiquitin-conjugating enzyme e2 2 protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	UCREL1_1257	Putative proliferating cell nuclear antigen protein. (412 aa)
	UCREL1_1256	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (279 aa)
	UCREL1_440	Putative impb mucb samb family protein. (1040 aa)

Your Current Organism:

Eutypa lata

NCBI taxonomy Id: 1287681
Other names: E. lata UCREL1, Eutypa lata UCREL1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
UCREL1_10853	UCREL1_11385	M7SDD3	M7T4Y4	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Putative horma domain-containing protein.	0.974
UCREL1_10853	UCREL1_1165	M7SDD3	M7T593	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Putative sister chromatid cohesion protein eso1 protein.	0.974
UCREL1_10853	UCREL1_1256	M7SDD3	M7TYE2	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.853
UCREL1_10853	UCREL1_1257	M7SDD3	M7TYD7	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Putative proliferating cell nuclear antigen protein.	0.853
UCREL1_10853	UCREL1_2448	M7SDD3	M7TV28	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Putative ubiquitin-conjugating enzyme e2 2 protein; Belongs to the ubiquitin-conjugating enzyme family.	0.476
UCREL1_10853	UCREL1_440	M7SDD3	M7U0Q9	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Putative impb mucb samb family protein.	0.919
UCREL1_10853	UCREL1_6540	M7SDD3	M7SJE0	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Putative dna polymerase iota protein.	0.873
UCREL1_10853	UCREL1_7576	M7SDD3	M7SM55	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Putative dna polymerase epsilon subunit b protein.	0.461
UCREL1_10853	UCREL1_8269	M7SDD3	M7SKA1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Uncharacterized protein.	0.875
UCREL1_10853	UCREL1_872	M7SDD3	M7SZN4	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Putative dna polymerase zeta catalytic subunit protein.	0.931
UCREL1_11385	UCREL1_10853	M7T4Y4	M7SDD3	Putative horma domain-containing protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.974
UCREL1_11385	UCREL1_1165	M7T4Y4	M7T593	Putative horma domain-containing protein.	Putative sister chromatid cohesion protein eso1 protein.	0.976
UCREL1_11385	UCREL1_1256	M7T4Y4	M7TYE2	Putative horma domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.770
UCREL1_11385	UCREL1_1257	M7T4Y4	M7TYD7	Putative horma domain-containing protein.	Putative proliferating cell nuclear antigen protein.	0.770
UCREL1_11385	UCREL1_2448	M7T4Y4	M7TV28	Putative horma domain-containing protein.	Putative ubiquitin-conjugating enzyme e2 2 protein; Belongs to the ubiquitin-conjugating enzyme family.	0.583
UCREL1_11385	UCREL1_440	M7T4Y4	M7U0Q9	Putative horma domain-containing protein.	Putative impb mucb samb family protein.	0.905
UCREL1_11385	UCREL1_6540	M7T4Y4	M7SJE0	Putative horma domain-containing protein.	Putative dna polymerase iota protein.	0.916
UCREL1_11385	UCREL1_7360	M7T4Y4	M7T7A9	Putative horma domain-containing protein.	Putative brca1 c terminus domain-containing protein.	0.971
UCREL1_11385	UCREL1_8269	M7T4Y4	M7SKA1	Putative horma domain-containing protein.	Uncharacterized protein.	0.971
UCREL1_11385	UCREL1_872	M7T4Y4	M7SZN4	Putative horma domain-containing protein.	Putative dna polymerase zeta catalytic subunit protein.	0.999