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FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (394 aa) | ||||
UCREL1_3201 | Putative exonuclease 1 protein. (258 aa) | ||||
UCREL1_3184 | Putative dna excision repair protein rad2 protein. (1289 aa) | ||||
UCREL1_8608 | Putative flap structure-specific endonuclease protein. (507 aa) | ||||
UCREL1_8849 | Putative flap structure-specific endonuclease protein. (744 aa) |