(49 nodes) WD40 repeat, conserved site network (Eutypa lata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UCREL1_11548	Putative guanine nucleotide-binding protein subunit beta-like protein. (316 aa)
	UCREL1_10293	Putative transcriptional repressor rco-1 protein. (599 aa)
	TIF34	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (336 aa)
	UCREL1_9974	Putative wd repeat-containing protein 2 protein. (639 aa)
	UCREL1_9766	Putative alpha-ketoglutarate-dependent taurine dioxygenase protein. (740 aa)
	UCREL1_11644	Putative f-box wd repeat-containing protein 7 protein. (569 aa)
	UCREL1_11224	Putative periodic tryptophan protein 1 protein. (540 aa)
	UCREL1_10861	Putative will die slowly protein. (526 aa)
	UCREL1_10791	Putative wd domain-containing protein. (376 aa)
	UCREL1_8560	Putative taf5-like protein. (804 aa)
	UCREL1_9967	Putative small nucleolar ribonucleoprotein complex subunit protein. (536 aa)
	UCREL1_7887	Putative f-box wd-40 repeat-containing protein. (958 aa)
	UCREL1_8918	Putative wd repeat-containing protein 70 protein. (572 aa)
	UCREL1_7920	Putative dom34-interacting protein 2 protein. (975 aa)
	UCREL1_7584	Putative wd-repeat containing protein slp1 protein. (605 aa)
	UCREL1_7730	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1222 aa)
	UCREL1_4425	Putative phosphoinositide 3-kinase regulatory subunit 4 protein. (1584 aa)
	UCREL1_5273	Putative wd repeat-containing protein. (449 aa)
	UCREL1_11671	Putative wd repeat containing protein 36 protein. (1044 aa)
	UCREL1_2112	Putative wd g-beta repeat containing protein. (1106 aa)
	UCREL1_4159	Putative wd repeat-containing protein. (307 aa)
	UCREL1_1772	Putative sulfur controller 2 protein. (531 aa)
	UCREL1_1206	Putative wd domain-containing protein. (490 aa)
	PAC1	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (486 aa)
	UCREL1_2900	Coronin; Belongs to the WD repeat coronin family. (588 aa)
	UCREL1_9236	Putative u3 small nucleolar rna associated protein. (447 aa)
	UCREL1_11724	Putative srebp cleavage activating protein. (1135 aa)
	UCREL1_1546	Putative wd domain-containing protein. (454 aa)
	UCREL1_353	Putative ribosome biogenesis protein sqt1 protein. (522 aa)
	UCREL1_9916	Putative pre-mrna-processing factor 17 protein. (533 aa)
	UCREL1_6553	Putative transcriptional repressor protein. (325 aa)
	UCREL1_9523	Putative cell division control protein. (1000 aa)
	UCREL1_9504	Putative histone acetyltransferase type b subunit 2 protein. (455 aa)
	UCREL1_6000	Putative meiotic recombination protein rec14 protein. (328 aa)
	UCREL1_5598	Putative wd repeat-containing protein. (150 aa)
	UCREL1_7544	Putative dna excision repair protein ercc-8 protein. (400 aa)
	UCREL1_3795	Putative pre-mrna splicing protein. (488 aa)
	UCREL1_3638	Putative mitochondrial division protein 1 protein. (601 aa)
	UCREL1_6757	Putative wd-repeat protein pop3 protein. (394 aa)
	UCREL1_6552	Putative minichromosome loss protein 1 protein. (835 aa)
	UCREL1_3251	Putative mitogen-activated protein kinase organizer 1 protein. (386 aa)
	UCREL1_5543	Putative wd domain protein. (433 aa)
	UCREL1_1959	Putative u4 u6 small nuclear ribonucleoprotein prp4 protein. (532 aa)
	UCREL1_1280	Putative wd domain-containing protein. (262 aa)
	UCREL1_4288	Putative nuclear distribution protein nudf protein. (242 aa)
	UCREL1_1650	Putative f-box and wd40 domain protein. (605 aa)
	UCREL1_937	Putative wd repeat-containing protein 5b protein. (662 aa)
	UCREL1_471	Putative periodic tryptophan protein 2 protein. (865 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (492 aa)

Your Current Organism:

Eutypa lata

NCBI taxonomy Id: 1287681
Other names: E. lata UCREL1, Eutypa lata UCREL1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PAC1	UCREL1_10791	M7SZU2	M7SDJ8	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative wd domain-containing protein.	0.488
PAC1	UCREL1_1959	M7SZU2	M7TM40	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative u4 u6 small nuclear ribonucleoprotein prp4 protein.	0.483
PAC1	UCREL1_3251	M7SZU2	M7TIE7	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative mitogen-activated protein kinase organizer 1 protein.	0.429
PAC1	UCREL1_4288	M7SZU2	M7TPS7	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative nuclear distribution protein nudf protein.	0.902
PAC1	UCREL1_5598	M7SZU2	M7TBX7	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative wd repeat-containing protein.	0.501
PAC1	UCREL1_6000	M7SZU2	M7TAX0	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative meiotic recombination protein rec14 protein.	0.487
PAC1	UCREL1_6553	M7SZU2	M7T9E7	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative transcriptional repressor protein.	0.487
PAC1	UCREL1_7584	M7SZU2	M7SM23	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative wd-repeat containing protein slp1 protein.	0.506
PAC1	UCREL1_8560	M7SZU2	M7SE22	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.	Putative taf5-like protein.	0.445
TIF34	UCREL1_11548	M7S9X0	M7S619	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative guanine nucleotide-binding protein subunit beta-like protein.	0.993
TIF34	UCREL1_1772	M7S9X0	M7SX78	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative sulfur controller 2 protein.	0.449
TIF34	UCREL1_1959	M7S9X0	M7TM40	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative u4 u6 small nuclear ribonucleoprotein prp4 protein.	0.475
TIF34	UCREL1_3251	M7S9X0	M7TIE7	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative mitogen-activated protein kinase organizer 1 protein.	0.400
TIF34	UCREL1_4288	M7S9X0	M7TPS7	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative nuclear distribution protein nudf protein.	0.470
TIF34	UCREL1_471	M7S9X0	M7U0M0	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative periodic tryptophan protein 2 protein.	0.418
TIF34	UCREL1_5273	M7S9X0	M7STY7	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative wd repeat-containing protein.	0.551
TIF34	UCREL1_5598	M7S9X0	M7TBX7	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative wd repeat-containing protein.	0.448
TIF34	UCREL1_6000	M7S9X0	M7TAX0	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative meiotic recombination protein rec14 protein.	0.451
TIF34	UCREL1_6553	M7S9X0	M7T9E7	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative transcriptional repressor protein.	0.437
TIF34	UCREL1_7887	M7S9X0	M7SFY2	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Putative f-box wd-40 repeat-containing protein.	0.402