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| | DVJ83_06330 | Unannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (437 aa) |
| | DVJ83_06335 | Unannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (419 aa) |
| | DVJ83_06340 | Unannotated protein. (343 aa) |
| | pdhA | Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (374 aa) |
| | pckA | Unannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (531 aa) |
| | sdhC | Unannotated protein. (118 aa) |
| | DVJ83_06470 | Unannotated protein. (125 aa) |
| | sdhA | Unannotated protein. (583 aa) |
| | DVJ83_06480 | Unannotated protein. (264 aa) |
| | trpA | Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (269 aa) |
| | trpB | Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (413 aa) |
| | DVJ83_06605 | Unannotated protein. (87 aa) |
| | DVJ83_06925 | Unannotated protein. (443 aa) |
| | metXA | Unannotated protein; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (329 aa) |
| | rpiA | Unannotated protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (226 aa) |
| | fsa | Unannotated protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (234 aa) |
| | tpiA | Unannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (245 aa) |
| | pgk | Unannotated protein; Belongs to the phosphoglycerate kinase family. (389 aa) |
| | gap | Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (330 aa) |
| | DVJ83_04095 | Unannotated protein. (389 aa) |
| | DVJ83_04150 | Unannotated protein; Belongs to the aspartokinase family. (473 aa) |
| | pdxT | Unannotated protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (196 aa) |
| | pdxS | Unannotated protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (71 aa) |
| | DVJ83_03420 | Unannotated protein; Belongs to the carbohydrate kinase PfkB family. (311 aa) |
| | DVJ83_03425 | Unannotated protein. (531 aa) |
| | proC | Unannotated protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa) |
| | ilvC | Unannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (336 aa) |
| | GCA_000348665_00325 | Unannotated protein. (205 aa) |
| | ilvB | Unannotated protein. (595 aa) |
| | DVJ83_03595 | Unannotated protein. (335 aa) |
| | leuA | Unannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (516 aa) |
| | DVJ83_02730 | Unannotated protein. (455 aa) |
| | acnA | Unannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (906 aa) |
| | pgi | Unannotated protein; Belongs to the GPI family. (539 aa) |
| | DVJ83_02505 | Unannotated protein. (204 aa) |
| | trpD | Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (359 aa) |
| | leuC | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (431 aa) |
| | leuD | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (207 aa) |
| | leuB | Unannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (352 aa) |
| | DVJ83_14500 | Unannotated protein. (490 aa) |
| | DVJ83_14620 | Unannotated protein; Belongs to the malate synthase family. (521 aa) |
| | leuC-2 | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (439 aa) |
| | leuD-2 | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (168 aa) |
| | DVJ83_05695 | Unannotated protein; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (355 aa) |
| | tdh | Unannotated protein; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (344 aa) |
| | DVJ83_05910 | Unannotated protein. (333 aa) |
| | gluQ | Unannotated protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (296 aa) |
| | DVJ83_11905 | Unannotated protein. (632 aa) |
| | trpF | Unannotated protein; Belongs to the TrpF family. (199 aa) |
| | DVJ83_14075 | Unannotated protein; Belongs to the aldehyde dehydrogenase family. (493 aa) |
| | rbsK | Unannotated protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (305 aa) |
| | deoB | Unannotated protein; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (388 aa) |
| | hisD | Unannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (436 aa) |
| | DVJ83_04820 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (542 aa) |
| | ppc | Unannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (829 aa) |
| | DVJ83_04850 | Unannotated protein. (320 aa) |
| | sucD | Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa) |
| | sucC | Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (407 aa) |
| | deoC | Unannotated protein; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa) |
| | aroE | Unannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (270 aa) |
| | DVJ83_05395 | Unannotated protein. (289 aa) |
| | DVJ83_03895 | Unannotated protein. (269 aa) |
| | hisB | Unannotated protein. (195 aa) |
| | hisH | Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (218 aa) |
| | DVJ83_08095 | Unannotated protein. (388 aa) |
| | pfkA | Unannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (334 aa) |
| | trpE | Unannotated protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (370 aa) |
| | gcvP | Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (948 aa) |
| | proA | Unannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (433 aa) |
| | proB | Unannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (363 aa) |
| | acs | Unannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa) |
| | hisC | Unannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (365 aa) |
| | DVJ83_07720 | Unannotated protein; Belongs to the peptidase M17 family. (449 aa) |
| | eno | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (422 aa) |
| | pyk | Unannotated protein; Belongs to the pyruvate kinase family. (482 aa) |
| | fumC | Unannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa) |
| | DVJ83_04305 | Unannotated protein. (262 aa) |
| | rpe | Unannotated protein; Belongs to the ribulose-phosphate 3-epimerase family. (223 aa) |
| | trpC | Unannotated protein; Belongs to the TrpC family. (268 aa) |
| | DVJ83_00275 | Unannotated protein. (310 aa) |
| | sdaAB | Unannotated protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (221 aa) |
| | pdxH | Unannotated protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (208 aa) |
| | gltX | Unannotated protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (477 aa) |
| | lpdA | Unannotated protein. (468 aa) |
| | aroC | Unannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (382 aa) |
| | aroK | Unannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (238 aa) |
| | aroB | Unannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (350 aa) |
| | DVJ83_12575 | Unannotated protein. (955 aa) |
| | DVJ83_09465 | Unannotated protein. (404 aa) |
| | hisF | Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (265 aa) |
| | hisI | Unannotated protein; In the N-terminal section; belongs to the PRA-CH family. (223 aa) |
| | DVJ83_07590 | Unannotated protein. (303 aa) |
| | DVJ83_07525 | Unannotated protein; Belongs to the citrate synthase family. (377 aa) |
| | lpdA-2 | Unannotated protein. (467 aa) |
| | ldh | Unannotated protein; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (304 aa) |
| | DVJ83_18735 | Unannotated protein. (597 aa) |
| | pfkB | Unannotated protein; Belongs to the carbohydrate kinase PfkB family. (313 aa) |
| | GCA_000348665_01828 | Unannotated protein. (836 aa) |
| | DVJ83_18710 | Unannotated protein. (267 aa) |
| | DVJ83_11570 | Unannotated protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (417 aa) |
| | DVJ83_11505 | Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (706 aa) |
| | ilvD | Unannotated protein; Belongs to the IlvD/Edd family. (607 aa) |
| | DVJ83_05505 | Unannotated protein. (371 aa) |
| | DVJ83_14215 | Unannotated protein; Belongs to the aldehyde dehydrogenase family. (528 aa) |
| | DVJ83_14220 | Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa) |
| | DVJ83_14305 | Unannotated protein; Belongs to the aldehyde dehydrogenase family. (516 aa) |
| | thrB | Unannotated protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (339 aa) |
| | tkt | Unannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (657 aa) |
| | aroA | Unannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (440 aa) |
| | zwf | Unannotated protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (547 aa) |
| | gnd | Unannotated protein. (362 aa) |
| | fba | Unannotated protein. (305 aa) |
| | DVJ83_00400 | Unannotated protein. (416 aa) |
| | DVJ83_07135 | Unannotated protein. (429 aa) |
| | DVJ83_07175 | Unannotated protein. (285 aa) |
| | DVJ83_07210 | Unannotated protein. (310 aa) |
| | pruA | Unannotated protein. (523 aa) |
| | hisA | Unannotated protein. (242 aa) |
| | glpX | Unannotated protein. (332 aa) |
| | asd | Unannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (336 aa) |
| | lysS | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (393 aa) |
| | DVJ83_11235 | Unannotated protein. (368 aa) |
| | DVJ83_11240 | Unannotated protein. (330 aa) |
| | DVJ83_11250 | Unannotated protein. (519 aa) |
| | glyA | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (408 aa) |
| | DVJ83_08830 | Unannotated protein; Belongs to the HpcH/HpaI aldolase family. (280 aa) |
| | apgM | Unannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (410 aa) |
| | DVJ83_08200 | Unannotated protein. (152 aa) |
| | DVJ83_10635 | Unannotated protein. (231 aa) |
| | DVJ83_12170 | Unannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (343 aa) |
| | aroF | Unannotated protein. (366 aa) |
| | ilvA | Unannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (520 aa) |
| | DVJ83_12275 | Unannotated protein. (1605 aa) |
| | DVJ83_12270 | Unannotated protein. (488 aa) |
| | sdaAA | Unannotated protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (299 aa) |
| | DVJ83_01200 | Unannotated protein; Belongs to the glutamine synthetase family. (719 aa) |
| | DVJ83_10735 | Unannotated protein. (581 aa) |
| | DVJ83_00010 | Unannotated protein. (447 aa) |
| | glnA | Unannotated protein; Belongs to the glutamine synthetase family. (449 aa) |
| | ackA | Unannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (413 aa) |
| | hisG | Unannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (217 aa) |
| | hisZ | Unannotated protein; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (409 aa) |
| | DVJ83_03355 | Unannotated protein. (416 aa) |
| | DVJ83_14360 | Unannotated protein. (470 aa) |
| | aceE | Unannotated protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (908 aa) |
| | aceF | Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (588 aa) |
| | DVJ83_18315 | Unannotated protein. (493 aa) |
| | mdh | Unannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (330 aa) |
| | DVJ83_09195 | Unannotated protein. (324 aa) |
| | DVJ83_04620 | Unannotated protein. (332 aa) |
| | pdxY | Unannotated protein; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. (307 aa) |
