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DVJ83_06330 DVJ83_06330 DVJ83_06335 DVJ83_06335 DVJ83_06340 DVJ83_06340 pdhA pdhA pckA pckA sdhC sdhC DVJ83_06470 DVJ83_06470 sdhA sdhA DVJ83_06480 DVJ83_06480 DVJ83_06605 DVJ83_06605 rpiA rpiA fsa fsa tpiA tpiA pgk pgk gap gap pdxT pdxT pdxS pdxS DVJ83_03420 DVJ83_03420 DVJ83_03425 DVJ83_03425 proC proC DVJ83_03595 DVJ83_03595 DVJ83_02730 DVJ83_02730 acnA acnA pgi pgi DVJ83_14500 DVJ83_14500 DVJ83_14620 DVJ83_14620 gluQ gluQ DVJ83_14075 DVJ83_14075 rbsK rbsK deoB deoB DVJ83_04820 DVJ83_04820 ppc ppc sucD sucD sucC sucC deoC deoC pfkA pfkA proA proA proB proB acs acs DVJ83_07720 DVJ83_07720 eno eno pyk pyk fumC fumC DVJ83_04305 DVJ83_04305 rpe rpe DVJ83_00275 DVJ83_00275 pdxH pdxH gltX gltX lpdA lpdA DVJ83_12575 DVJ83_12575 DVJ83_07590 DVJ83_07590 DVJ83_07525 DVJ83_07525 lpdA-2 lpdA-2 ldh ldh DVJ83_18735 DVJ83_18735 pfkB pfkB GCA_000348665_01828 GCA_000348665_01828 DVJ83_18710 DVJ83_18710 DVJ83_11570 DVJ83_11570 DVJ83_11505 DVJ83_11505 DVJ83_14215 DVJ83_14215 DVJ83_14220 DVJ83_14220 DVJ83_14305 DVJ83_14305 tkt tkt zwf zwf gnd gnd fba fba DVJ83_07135 DVJ83_07135 DVJ83_07175 DVJ83_07175 DVJ83_07210 DVJ83_07210 pruA pruA glpX glpX DVJ83_11235 DVJ83_11235 DVJ83_11240 DVJ83_11240 DVJ83_11250 DVJ83_11250 DVJ83_08830 DVJ83_08830 apgM apgM DVJ83_08200 DVJ83_08200 DVJ83_10635 DVJ83_10635 DVJ83_12170 DVJ83_12170 DVJ83_12275 DVJ83_12275 DVJ83_12270 DVJ83_12270 DVJ83_01200 DVJ83_01200 DVJ83_10735 DVJ83_10735 DVJ83_00010 DVJ83_00010 glnA glnA ackA ackA DVJ83_03355 DVJ83_03355 aceE aceE aceF aceF DVJ83_18315 DVJ83_18315 mdh mdh DVJ83_09195 DVJ83_09195 DVJ83_04620 DVJ83_04620 pdxY pdxY
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DVJ83_06330Unannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (437 aa)
DVJ83_06335Unannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (419 aa)
DVJ83_06340Unannotated protein. (343 aa)
pdhAUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (374 aa)
pckAUnannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (531 aa)
sdhCUnannotated protein. (118 aa)
DVJ83_06470Unannotated protein. (125 aa)
sdhAUnannotated protein. (583 aa)
DVJ83_06480Unannotated protein. (264 aa)
DVJ83_06605Unannotated protein. (87 aa)
rpiAUnannotated protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (226 aa)
fsaUnannotated protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (234 aa)
tpiAUnannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (245 aa)
pgkUnannotated protein; Belongs to the phosphoglycerate kinase family. (389 aa)
gapUnannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (330 aa)
pdxTUnannotated protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (196 aa)
pdxSUnannotated protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (71 aa)
DVJ83_03420Unannotated protein; Belongs to the carbohydrate kinase PfkB family. (311 aa)
DVJ83_03425Unannotated protein. (531 aa)
proCUnannotated protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa)
DVJ83_03595Unannotated protein. (335 aa)
DVJ83_02730Unannotated protein. (455 aa)
acnAUnannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (906 aa)
pgiUnannotated protein; Belongs to the GPI family. (539 aa)
DVJ83_14500Unannotated protein. (490 aa)
DVJ83_14620Unannotated protein; Belongs to the malate synthase family. (521 aa)
gluQUnannotated protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (296 aa)
DVJ83_14075Unannotated protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
rbsKUnannotated protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (305 aa)
deoBUnannotated protein; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (388 aa)
DVJ83_04820Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (542 aa)
ppcUnannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (829 aa)
sucDUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa)
sucCUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (407 aa)
deoCUnannotated protein; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa)
pfkAUnannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (334 aa)
proAUnannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (433 aa)
proBUnannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (363 aa)
acsUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa)
DVJ83_07720Unannotated protein; Belongs to the peptidase M17 family. (449 aa)
enoUnannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (422 aa)
pykUnannotated protein; Belongs to the pyruvate kinase family. (482 aa)
fumCUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
DVJ83_04305Unannotated protein. (262 aa)
rpeUnannotated protein; Belongs to the ribulose-phosphate 3-epimerase family. (223 aa)
DVJ83_00275Unannotated protein. (310 aa)
pdxHUnannotated protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (208 aa)
gltXUnannotated protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (477 aa)
lpdAUnannotated protein. (468 aa)
DVJ83_12575Unannotated protein. (955 aa)
DVJ83_07590Unannotated protein. (303 aa)
DVJ83_07525Unannotated protein; Belongs to the citrate synthase family. (377 aa)
lpdA-2Unannotated protein. (467 aa)
ldhUnannotated protein; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (304 aa)
DVJ83_18735Unannotated protein. (597 aa)
pfkBUnannotated protein; Belongs to the carbohydrate kinase PfkB family. (313 aa)
GCA_000348665_01828Unannotated protein. (836 aa)
DVJ83_18710Unannotated protein. (267 aa)
DVJ83_11570Unannotated protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (417 aa)
DVJ83_11505Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (706 aa)
DVJ83_14215Unannotated protein; Belongs to the aldehyde dehydrogenase family. (528 aa)
DVJ83_14220Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
DVJ83_14305Unannotated protein; Belongs to the aldehyde dehydrogenase family. (516 aa)
tktUnannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (657 aa)
zwfUnannotated protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (547 aa)
gndUnannotated protein. (362 aa)
fbaUnannotated protein. (305 aa)
DVJ83_07135Unannotated protein. (429 aa)
DVJ83_07175Unannotated protein. (285 aa)
DVJ83_07210Unannotated protein. (310 aa)
pruAUnannotated protein. (523 aa)
glpXUnannotated protein. (332 aa)
DVJ83_11235Unannotated protein. (368 aa)
DVJ83_11240Unannotated protein. (330 aa)
DVJ83_11250Unannotated protein. (519 aa)
DVJ83_08830Unannotated protein; Belongs to the HpcH/HpaI aldolase family. (280 aa)
apgMUnannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (410 aa)
DVJ83_08200Unannotated protein. (152 aa)
DVJ83_10635Unannotated protein. (231 aa)
DVJ83_12170Unannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (343 aa)
DVJ83_12275Unannotated protein. (1605 aa)
DVJ83_12270Unannotated protein. (488 aa)
DVJ83_01200Unannotated protein; Belongs to the glutamine synthetase family. (719 aa)
DVJ83_10735Unannotated protein. (581 aa)
DVJ83_00010Unannotated protein. (447 aa)
glnAUnannotated protein; Belongs to the glutamine synthetase family. (449 aa)
ackAUnannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (413 aa)
DVJ83_03355Unannotated protein. (416 aa)
aceEUnannotated protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (908 aa)
aceFUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (588 aa)
DVJ83_18315Unannotated protein. (493 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (330 aa)
DVJ83_09195Unannotated protein. (324 aa)
DVJ83_04620Unannotated protein. (332 aa)
pdxYUnannotated protein; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. (307 aa)
Your Current Organism:
Deinococcus wulumuqiensis
NCBI taxonomy Id: 1288484
Other names: D. wulumuqiensis R12, Deinococcus wulumuqiensis DSM 28115, Deinococcus wulumuqiensis R12
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