STRINGSTRING
DVJ83_06340 DVJ83_06340 pdhA pdhA pckA pckA lysY lysY sdhC sdhC DVJ83_06470 DVJ83_06470 sdhA sdhA DVJ83_06480 DVJ83_06480 trpA trpA trpB trpB DVJ83_06590 DVJ83_06590 metXA metXA purH purH DVJ83_06980 DVJ83_06980 crtI crtI DVJ83_07040 DVJ83_07040 rpiA rpiA fsa fsa tpiA tpiA pgk pgk gap gap DVJ83_04095 DVJ83_04095 DVJ83_04150 DVJ83_04150 DVJ83_04205 DVJ83_04205 hpt hpt ilvC ilvC ilvB ilvB DVJ83_03500 DVJ83_03500 dxr dxr leuA leuA dxs dxs DVJ83_02750 DVJ83_02750 acnA acnA ppsA ppsA DVJ83_02655 DVJ83_02655 pgi pgi lysA lysA DVJ83_02505 DVJ83_02505 leuC leuC leuD leuD leuB leuB DVJ83_14520 DVJ83_14520 DVJ83_14620 DVJ83_14620 DVJ83_14635 DVJ83_14635 DVJ83_14715 DVJ83_14715 leuC-2 leuC-2 leuD-2 leuD-2 xpt xpt DVJ83_05695 DVJ83_05695 malQ malQ mqnB mqnB rocD rocD DVJ83_05910 DVJ83_05910 gluQ gluQ glgC glgC miaA miaA guaB guaB purC purC purS purS purQ purQ purL purL purF purF DVJ83_11950 DVJ83_11950 accC accC trpF trpF DVJ83_14075 DVJ83_14075 DVJ83_14130 DVJ83_14130 DVJ83_14205 DVJ83_14205 DVJ83_14210 DVJ83_14210 adk adk hisD hisD DVJ83_00570 DVJ83_00570 ispH ispH DVJ83_04820 DVJ83_04820 DVJ83_04850 DVJ83_04850 DVJ83_04935 DVJ83_04935 sucD sucD sucC sucC aroE aroE panC panC DVJ83_05395 DVJ83_05395 DVJ83_03895 DVJ83_03895 pulA pulA hisB hisB hisH hisH DVJ83_08095 DVJ83_08095 pfkA pfkA metK metK rocF rocF argG argG argH argH DVJ83_07885 DVJ83_07885 DVJ83_01585 DVJ83_01585 DVJ83_01625 DVJ83_01625 fabD fabD fabG fabG acpP acpP trpE trpE gcvP gcvP gcvT gcvT DVJ83_02285 DVJ83_02285 DVJ83_02245 DVJ83_02245 proA proA proB proB glgB glgB acs acs hisC hisC DVJ83_10080 DVJ83_10080 argB argB DVJ83_07770 DVJ83_07770 DVJ83_07765 DVJ83_07765 panD panD eno eno pyk pyk fumC fumC gpsA gpsA ctaB ctaB DVJ83_10965 DVJ83_10965 panB panB purM purM DVJ83_04300 DVJ83_04300 rpe rpe lysZ lysZ trpC trpC DVJ83_04470 DVJ83_04470 purD purD DVJ83_00350 DVJ83_00350 DVJ83_00300 DVJ83_00300 sdaAB sdaAB gltX gltX lpdA lpdA aroC aroC aroK aroK aroB aroB aroQ aroQ DVJ83_07380 DVJ83_07380 cysK cysK lysJ lysJ DVJ83_12520 DVJ83_12520 DVJ83_12575 DVJ83_12575 DVJ83_12665 DVJ83_12665 DVJ83_07695 DVJ83_07695 hisF hisF hisI hisI DVJ83_07590 DVJ83_07590 DVJ83_07525 DVJ83_07525 lpdA-2 lpdA-2 ldh ldh DVJ83_09500 DVJ83_09500 hemC hemC DVJ83_11570 DVJ83_11570 mqnC mqnC DVJ83_05420 DVJ83_05420 hemE hemE ilvD ilvD hemH hemH hemG hemG DVJ83_05505 DVJ83_05505 DVJ83_14260 DVJ83_14260 DVJ83_14305 DVJ83_14305 surE surE thrB thrB tkt tkt fni fni aroA aroA zwf zwf gnd gnd fba fba DVJ83_03110 DVJ83_03110 DVJ83_00455 DVJ83_00455 deoD deoD DVJ83_12810 DVJ83_12810 DVJ83_07135 DVJ83_07135 DVJ83_07165 DVJ83_07165 DVJ83_07175 DVJ83_07175 DVJ83_07180 DVJ83_07180 DVJ83_07210 DVJ83_07210 ndk ndk hisA hisA DVJ83_10215 DVJ83_10215 glpX glpX asd asd DVJ83_01425 DVJ83_01425 plsX plsX lysS lysS accD accD accA accA purE purE purK purK DVJ83_11235 DVJ83_11235 DVJ83_11240 DVJ83_11240 DVJ83_11250 DVJ83_11250 glyA glyA apgM apgM DVJ83_11615 DVJ83_11615 ispF ispF glgA glgA DVJ83_08200 DVJ83_08200 DVJ83_10635 DVJ83_10635 DVJ83_10625 DVJ83_10625 hemA hemA ribD ribD DVJ83_12155 DVJ83_12155 ribBA ribBA ribH ribH DVJ83_12170 DVJ83_12170 aroF aroF ribF ribF mqnD mqnD DVJ83_08530 DVJ83_08530 hemL hemL ilvA ilvA DVJ83_12280 DVJ83_12280 DVJ83_12275 DVJ83_12275 DVJ83_12270 DVJ83_12270 DVJ83_13650 DVJ83_13650 mqnE mqnE mqnA mqnA sdaAA sdaAA treS treS DVJ83_10815 DVJ83_10815 DVJ83_10790 DVJ83_10790 DVJ83_10755 DVJ83_10755 DVJ83_03235 DVJ83_03235 treZ treZ treY treY ubiX ubiX ispD ispD ispE ispE DVJ83_04605 DVJ83_04605 hisG hisG hisZ hisZ DVJ83_03355 DVJ83_03355 DVJ83_03165 DVJ83_03165 DVJ83_02910 DVJ83_02910 argJ argJ DVJ83_09870 DVJ83_09870 menG menG DVJ83_14360 DVJ83_14360 glgX glgX aceE aceE aceF aceF sat sat cobA cobA plsY plsY purN purN menC menC mdh mdh DVJ83_08920 DVJ83_08920 DVJ83_09195 DVJ83_09195 ispG ispG DVJ83_06140 DVJ83_06140 DVJ83_04620 DVJ83_04620 DVJ83_03920 DVJ83_03920 DVJ83_07705 DVJ83_07705 DVJ83_18395 DVJ83_18395
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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DVJ83_06340Unannotated protein. (343 aa)
pdhAUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (374 aa)
pckAUnannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (531 aa)
lysYUnannotated protein; Catalyzes the NADPH-dependent reduction of [LysW]- aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (348 aa)
sdhCUnannotated protein. (118 aa)
DVJ83_06470Unannotated protein. (125 aa)
sdhAUnannotated protein. (583 aa)
DVJ83_06480Unannotated protein. (264 aa)
trpAUnannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (269 aa)
trpBUnannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (413 aa)
DVJ83_06590Unannotated protein; Belongs to the FPP/GGPP synthase family. (333 aa)
metXAUnannotated protein; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (329 aa)
purHUnannotated protein. (511 aa)
DVJ83_06980Unannotated protein. (308 aa)
crtIUnannotated protein. (548 aa)
DVJ83_07040Unannotated protein; Belongs to the UbiA prenyltransferase family. (298 aa)
rpiAUnannotated protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (226 aa)
fsaUnannotated protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (234 aa)
tpiAUnannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (245 aa)
pgkUnannotated protein; Belongs to the phosphoglycerate kinase family. (389 aa)
gapUnannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (330 aa)
DVJ83_04095Unannotated protein. (389 aa)
DVJ83_04150Unannotated protein; Belongs to the aspartokinase family. (473 aa)
DVJ83_04205Unannotated protein. (532 aa)
hptUnannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (178 aa)
ilvCUnannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (336 aa)
ilvBUnannotated protein. (595 aa)
DVJ83_03500Unannotated protein; Belongs to the CDS family. (277 aa)
dxrUnannotated protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (391 aa)
leuAUnannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (516 aa)
dxsUnannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (629 aa)
DVJ83_02750Unannotated protein. (356 aa)
acnAUnannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (906 aa)
ppsAUnannotated protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (780 aa)
DVJ83_02655Unannotated protein. (460 aa)
pgiUnannotated protein; Belongs to the GPI family. (539 aa)
lysAUnannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (61 aa)
DVJ83_02505Unannotated protein. (204 aa)
leuCUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (431 aa)
leuDUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (207 aa)
leuBUnannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (352 aa)
DVJ83_14520Unannotated protein; Belongs to the 5'-nucleotidase family. (524 aa)
DVJ83_14620Unannotated protein; Belongs to the malate synthase family. (521 aa)
DVJ83_14635Unannotated protein. (526 aa)
DVJ83_14715Unannotated protein; Serves to protect cells from the toxic effects of hydrogen peroxide. (758 aa)
leuC-2Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (439 aa)
leuD-2Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (168 aa)
xptUnannotated protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (193 aa)
DVJ83_05695Unannotated protein; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (355 aa)
malQUnannotated protein. (502 aa)
mqnBUnannotated protein; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). (223 aa)
rocDUnannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
DVJ83_05910Unannotated protein. (333 aa)
gluQUnannotated protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (296 aa)
glgCUnannotated protein; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (413 aa)
miaAUnannotated protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (302 aa)
guaBUnannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa)
purCUnannotated protein; Belongs to the SAICAR synthetase family. (245 aa)
purSUnannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (82 aa)
purQUnannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (219 aa)
purLUnannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (742 aa)
purFUnannotated protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (472 aa)
DVJ83_11950Unannotated protein. (252 aa)
accCUnannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (445 aa)
trpFUnannotated protein; Belongs to the TrpF family. (199 aa)
DVJ83_14075Unannotated protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
DVJ83_14130Unannotated protein. (203 aa)
DVJ83_14205Unannotated protein. (306 aa)
DVJ83_14210Unannotated protein. (352 aa)
adkUnannotated protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (196 aa)
hisDUnannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (436 aa)
DVJ83_00570Unannotated protein; Belongs to the ALAD family. (330 aa)
ispHUnannotated protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (337 aa)
DVJ83_04820Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (542 aa)
DVJ83_04850Unannotated protein. (320 aa)
DVJ83_04935Unannotated protein. (405 aa)
sucDUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa)
sucCUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (407 aa)
aroEUnannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (270 aa)
panCUnannotated protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (313 aa)
DVJ83_05395Unannotated protein. (289 aa)
DVJ83_03895Unannotated protein. (269 aa)
pulAUnannotated protein; Belongs to the glycosyl hydrolase 13 family. (985 aa)
hisBUnannotated protein. (195 aa)
hisHUnannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (218 aa)
DVJ83_08095Unannotated protein. (388 aa)
pfkAUnannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (334 aa)
metKUnannotated protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (408 aa)
rocFUnannotated protein; Belongs to the arginase family. (301 aa)
argGUnannotated protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (402 aa)
argHUnannotated protein. (466 aa)
DVJ83_07885Unannotated protein. (177 aa)
DVJ83_01585Unannotated protein. (264 aa)
DVJ83_01625Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
fabDUnannotated protein. (305 aa)
fabGUnannotated protein; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (254 aa)
acpPUnannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (76 aa)
trpEUnannotated protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (370 aa)
gcvPUnannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (948 aa)
gcvTUnannotated protein; The glycine cleavage system catalyzes the degradation of glycine. (334 aa)
DVJ83_02285Unannotated protein; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (365 aa)
DVJ83_02245Unannotated protein; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (423 aa)
proAUnannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (433 aa)
proBUnannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (363 aa)
glgBUnannotated protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (703 aa)
acsUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa)
hisCUnannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (365 aa)
DVJ83_10080Unannotated protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (274 aa)
argBUnannotated protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (249 aa)
DVJ83_07770Unannotated protein. (288 aa)
DVJ83_07765Unannotated protein. (247 aa)
panDUnannotated protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (116 aa)
enoUnannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (422 aa)
pykUnannotated protein; Belongs to the pyruvate kinase family. (482 aa)
fumCUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
gpsAUnannotated protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (328 aa)
ctaBUnannotated protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (313 aa)
DVJ83_10965Unannotated protein. (332 aa)
panBUnannotated protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (283 aa)
purMUnannotated protein. (360 aa)
DVJ83_04300Unannotated protein; Belongs to the FPP/GGPP synthase family. (329 aa)
rpeUnannotated protein; Belongs to the ribulose-phosphate 3-epimerase family. (223 aa)
lysZUnannotated protein; Catalyzes the phosphorylation of LysW-gamma-alpha- aminoadipate; Belongs to the acetylglutamate kinase family. LysZ subfamily. (267 aa)
trpCUnannotated protein; Belongs to the TrpC family. (268 aa)
DVJ83_04470Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
purDUnannotated protein; Belongs to the GARS family. (415 aa)
DVJ83_00350Unannotated protein. (838 aa)
DVJ83_00300Unannotated protein; Belongs to the 5'-nucleotidase family. (561 aa)
sdaABUnannotated protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (221 aa)
gltXUnannotated protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (477 aa)
lpdAUnannotated protein. (468 aa)
aroCUnannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (382 aa)
aroKUnannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (238 aa)
aroBUnannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (350 aa)
aroQUnannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (143 aa)
DVJ83_07380Unannotated protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (255 aa)
cysKUnannotated protein; Belongs to the cysteine synthase/cystathionine beta- synthase family. (316 aa)
lysJUnannotated protein; Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (425 aa)
DVJ83_12520Unannotated protein. (288 aa)
DVJ83_12575Unannotated protein. (955 aa)
DVJ83_12665Unannotated protein. (544 aa)
DVJ83_07695Unannotated protein. (303 aa)
hisFUnannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (265 aa)
hisIUnannotated protein; In the N-terminal section; belongs to the PRA-CH family. (223 aa)
DVJ83_07590Unannotated protein. (303 aa)
DVJ83_07525Unannotated protein; Belongs to the citrate synthase family. (377 aa)
lpdA-2Unannotated protein. (467 aa)
ldhUnannotated protein; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (304 aa)
DVJ83_09500Unannotated protein. (322 aa)
hemCUnannotated protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (310 aa)
DVJ83_11570Unannotated protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (417 aa)
mqnCUnannotated protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (409 aa)
DVJ83_05420Unannotated protein. (512 aa)
hemEUnannotated protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (393 aa)
ilvDUnannotated protein; Belongs to the IlvD/Edd family. (607 aa)
hemHUnannotated protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (319 aa)
hemGUnannotated protein; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (451 aa)
DVJ83_05505Unannotated protein. (371 aa)
DVJ83_14260Unannotated protein. (386 aa)
DVJ83_14305Unannotated protein; Belongs to the aldehyde dehydrogenase family. (516 aa)
surEUnannotated protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (269 aa)
thrBUnannotated protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (339 aa)
tktUnannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (657 aa)
fniUnannotated protein; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (333 aa)
aroAUnannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (440 aa)
zwfUnannotated protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (547 aa)
gndUnannotated protein. (362 aa)
fbaUnannotated protein. (305 aa)
DVJ83_03110Unannotated protein. (402 aa)
DVJ83_00455Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (435 aa)
deoDUnannotated protein. (245 aa)
DVJ83_12810Unannotated protein; Belongs to the UbiD family. (633 aa)
DVJ83_07135Unannotated protein. (429 aa)
DVJ83_07165Unannotated protein. (398 aa)
DVJ83_07175Unannotated protein. (285 aa)
DVJ83_07180Unannotated protein. (242 aa)
DVJ83_07210Unannotated protein. (310 aa)
ndkUnannotated protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (132 aa)
hisAUnannotated protein. (242 aa)
DVJ83_10215Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
glpXUnannotated protein. (332 aa)
asdUnannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (336 aa)
DVJ83_01425Unannotated protein; Belongs to the catalase family. (536 aa)
plsXUnannotated protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (357 aa)
lysSUnannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (393 aa)
accDUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (284 aa)
accAUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (327 aa)
purEUnannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (161 aa)
purKUnannotated protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (370 aa)
DVJ83_11235Unannotated protein. (368 aa)
DVJ83_11240Unannotated protein. (330 aa)
DVJ83_11250Unannotated protein. (519 aa)
glyAUnannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (408 aa)
apgMUnannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (410 aa)
DVJ83_11615Unannotated protein. (210 aa)
ispFUnannotated protein; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (172 aa)
glgAUnannotated protein; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (461 aa)
DVJ83_08200Unannotated protein. (152 aa)
DVJ83_10635Unannotated protein. (231 aa)
DVJ83_10625Unannotated protein. (213 aa)
hemAUnannotated protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (370 aa)
ribDUnannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (361 aa)
DVJ83_12155Unannotated protein. (222 aa)
ribBAUnannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (405 aa)
ribHUnannotated protein; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (164 aa)
DVJ83_12170Unannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (343 aa)
aroFUnannotated protein. (366 aa)
ribFUnannotated protein; Belongs to the ribF family. (297 aa)
mqnDUnannotated protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (300 aa)
DVJ83_08530Unannotated protein. (452 aa)
hemLUnannotated protein. (444 aa)
ilvAUnannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (520 aa)
DVJ83_12280Unannotated protein; Belongs to the enoyl-CoA hydratase/isomerase family. (277 aa)
DVJ83_12275Unannotated protein. (1605 aa)
DVJ83_12270Unannotated protein. (488 aa)
DVJ83_13650Unannotated protein. (415 aa)
mqnEUnannotated protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (392 aa)
mqnAUnannotated protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (284 aa)
sdaAAUnannotated protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (299 aa)
treSUnannotated protein. (552 aa)
DVJ83_10815Unannotated protein; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily. (344 aa)
DVJ83_10790Unannotated protein. (487 aa)
DVJ83_10755Unannotated protein. (210 aa)
DVJ83_03235Unannotated protein. (306 aa)
treZUnannotated protein. (613 aa)
treYUnannotated protein. (956 aa)
ubiXUnannotated protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (183 aa)
ispDUnannotated protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (222 aa)
ispEUnannotated protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (277 aa)
DVJ83_04605Unannotated protein. (401 aa)
hisGUnannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (217 aa)
hisZUnannotated protein; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (409 aa)
DVJ83_03355Unannotated protein. (416 aa)
DVJ83_03165Unannotated protein. (220 aa)
DVJ83_02910Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
argJUnannotated protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (391 aa)
DVJ83_09870Unannotated protein. (159 aa)
menGUnannotated protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (241 aa)
DVJ83_14360Unannotated protein. (470 aa)
glgXUnannotated protein; Belongs to the glycosyl hydrolase 13 family. (715 aa)
aceEUnannotated protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (908 aa)
aceFUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (588 aa)
satUnannotated protein; Belongs to the sulfate adenylyltransferase family. (388 aa)
cobAUnannotated protein. (503 aa)
plsYUnannotated protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (198 aa)
purNUnannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (196 aa)
menCUnannotated protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (375 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (330 aa)
DVJ83_08920Unannotated protein. (467 aa)
DVJ83_09195Unannotated protein. (324 aa)
ispGUnannotated protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (424 aa)
DVJ83_06140Unannotated protein. (531 aa)
DVJ83_04620Unannotated protein. (332 aa)
DVJ83_03920Unannotated protein. (378 aa)
DVJ83_07705Unannotated protein. (606 aa)
DVJ83_18395Unannotated protein; Belongs to the WrbA family. (201 aa)
Your Current Organism:
Deinococcus wulumuqiensis
NCBI taxonomy Id: 1288484
Other names: D. wulumuqiensis R12, Deinococcus wulumuqiensis DSM 28115, Deinococcus wulumuqiensis R12
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