STRINGSTRING
BcDW1_10684 BcDW1_10684 BcDW1_8949 BcDW1_8949 BcDW1_8559 BcDW1_8559 BcDW1_10852 BcDW1_10852 BcDW1_10719 BcDW1_10719 BcDW1_8086 BcDW1_8086 BcDW1_8933 BcDW1_8933 BcDW1_6745 BcDW1_6745 BcDW1_9127 BcDW1_9127 BcDW1_6730 BcDW1_6730 BcDW1_6704 BcDW1_6704 BcDW1_8716 BcDW1_8716 BcDW1_8420 BcDW1_8420 BcDW1_6206 BcDW1_6206 BcDW1_8463 BcDW1_8463 BcDW1_5519 BcDW1_5519 BcDW1_7371 BcDW1_7371 BcDW1_6994 BcDW1_6994 BcDW1_6808 BcDW1_6808 BcDW1_6326 BcDW1_6326 BcDW1_6046 BcDW1_6046 BcDW1_5279 BcDW1_5279 BcDW1_5174 BcDW1_5174 BcDW1_5065 BcDW1_5065 BcDW1_4878 BcDW1_4878 BcDW1_4336 BcDW1_4336 BcDW1_4426 BcDW1_4426 BcDW1_1839 BcDW1_1839 BcDW1_10419 BcDW1_10419 BcDW1_3257 BcDW1_3257 BcDW1_9488 BcDW1_9488 BcDW1_2235 BcDW1_2235 BcDW1_9319 BcDW1_9319 BcDW1_1862 BcDW1_1862 BcDW1_972 BcDW1_972 BcDW1_7382 BcDW1_7382 BcDW1_10674 BcDW1_10674 BcDW1_10587 BcDW1_10587 BcDW1_108 BcDW1_108 BcDW1_6641 BcDW1_6641 BcDW1_6457 BcDW1_6457 BcDW1_9526 BcDW1_9526 BcDW1_9170 BcDW1_9170 BcDW1_8223 BcDW1_8223 FEN1 FEN1 BcDW1_7619 BcDW1_7619 BcDW1_4254 BcDW1_4254 BcDW1_6746 BcDW1_6746 BcDW1_3161 BcDW1_3161 BcDW1_6108 BcDW1_6108 BcDW1_2581 BcDW1_2581 BcDW1_2510 BcDW1_2510 BcDW1_2178 BcDW1_2178 BcDW1_1650 BcDW1_1650 BcDW1_4456 BcDW1_4456 BcDW1_4363 BcDW1_4363 BcDW1_2466 BcDW1_2466
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BcDW1_10684Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2915 aa)
BcDW1_8949Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (647 aa)
BcDW1_8559DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (349 aa)
BcDW1_10852Putative swi snf family dna-dependent atpase protein. (1409 aa)
BcDW1_10719DNA ligase. (868 aa)
BcDW1_8086Putative aaa family protein. (1211 aa)
BcDW1_8933Putative atp-dependent dna helicase mph1 protein. (1229 aa)
BcDW1_6745Putative chromosome transmission fidelity protein. (1003 aa)
BcDW1_9127Putative dna repair and recombination protein rad54 protein. (862 aa)
BcDW1_6730Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (609 aa)
BcDW1_6704Putative rad55 protein. (383 aa)
BcDW1_8716Putative family helicase protein. (1780 aa)
BcDW1_8420Putative replication factor c subunit 1 protein. (681 aa)
BcDW1_6206Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2465 aa)
BcDW1_8463Putative sister chromatid cohesion acetyltransferase eco1 protein. (634 aa)
BcDW1_5519Putative dna repair protein rad50 protein. (1249 aa)
BcDW1_7371Putative ubiquitin conjugating enzyme protein; Belongs to the ubiquitin-conjugating enzyme family. (150 aa)
BcDW1_6994Putative mediated genome instability protein rmi1 protein. (274 aa)
BcDW1_6808Putative snf2 family helicase atpase protein. (2098 aa)
BcDW1_6326Putative dna repair protein rad57 protein. (485 aa)
BcDW1_6046Uncharacterized protein. (162 aa)
BcDW1_5279Putative activator 1 41 kDa subunit protein. (344 aa)
BcDW1_5174Putative dsdna-dependent atpase protein. (962 aa)
BcDW1_5065Putative signal transducer protein. (1257 aa)
BcDW1_4878Putative crossover junction endonuclease mus81 protein. (613 aa)
BcDW1_4336ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (480 aa)
BcDW1_4426Putative rad52 dna repair protein radc protein. (572 aa)
BcDW1_1839Putative dna repair exonuclease rad1 protein. (344 aa)
BcDW1_10419Checkpoint protein; Belongs to the HUS1 family. (344 aa)
BcDW1_3257DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (665 aa)
BcDW1_9488Putative replication protein a 32 kDa subunit protein. (333 aa)
BcDW1_2235Putative ubiquitin-conjugating enzyme protein. (138 aa)
BcDW1_9319Putative proliferating cell nuclear antigen protein. (627 aa)
BcDW1_1862Putative flap structure-specific endonuclease protein. (939 aa)
BcDW1_972DNA ligase. (923 aa)
BcDW1_7382Putative dna replication atp-dependent helicase dna2 protein. (1647 aa)
BcDW1_10674Putative dna repair protein rad5 protein. (1142 aa)
BcDW1_10587zf-GRF domain-containing protein. (381 aa)
BcDW1_108Putative snf2 family helicase protein. (1505 aa)
BcDW1_6641Putative meiotic recombination protein dmc1 protein; Belongs to the RecA family. (359 aa)
BcDW1_6457Putative replication factor c subunit 3 protein. (390 aa)
BcDW1_9526Putative cell cycle checkpoint protein rad17 protein. (948 aa)
BcDW1_9170Putative atp-depentend dna helicase protein. (999 aa)
BcDW1_8223Putative replication factor c subunit 4 protein. (355 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (399 aa)
BcDW1_7619Putative dna repair protein rad9 protein. (439 aa)
BcDW1_4254Replication factor C subunit 1. (1069 aa)
BcDW1_6746Uncharacterized protein. (80 aa)
BcDW1_3161Putative 3-5 exonuclease helicase protein. (664 aa)
BcDW1_6108Pectinesterase; Involved in maceration and soft-rotting of plant tissue. (332 aa)
BcDW1_2581Putative exonuclease 1 protein. (768 aa)
BcDW1_2510Putative activator 1 38 kDa subunit protein. (354 aa)
BcDW1_2178Uncharacterized protein. (522 aa)
BcDW1_1650Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (758 aa)
BcDW1_4456Putative dna repair protein. (719 aa)
BcDW1_4363Putative sister chromatid cohesion protein ctf8 protein. (166 aa)
BcDW1_2466Putative postreplication repair e3 ubiquitin-protein ligase rad18 protein. (486 aa)
Your Current Organism:
Botrytis cinerea BcDW1
NCBI taxonomy Id: 1290391
Other names: B. cinerea BcDW1, Botryotinia fuckeliana BcDW1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.