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TPE_0041 TPE_0041 TPE_0072 TPE_0072 eno eno ppdK ppdK TPE_0438 TPE_0438 TPE_0516 TPE_0516 deoC deoC prs prs pgi pgi TPE_0803 TPE_0803 fda fda TPE_0985 TPE_0985 pta pta rpe rpe TPE_1189 TPE_1189 pgk pgk TPE_1458 TPE_1458 TPE_1459 TPE_1459 gap gap TPE_1890 TPE_1890 ackA ackA rpiA rpiA tkt tkt TPE_2051 TPE_2051 TPE_2214 TPE_2214 pyk pyk TPE_2364 TPE_2364 TPE_2574 TPE_2574 pfp pfp tpiA tpiA gpmA gpmA pfk pfk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TPE_0041Pyruvate phosphate dikinase. (976 aa)
TPE_0072Hexokinase. (436 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (433 aa)
ppdKPyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (939 aa)
TPE_0438Phosphoglycerate mutase. (199 aa)
TPE_0516KHG/KDPG family aldolase/carbohydrate kinase. (598 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (216 aa)
prsPhosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (417 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (525 aa)
TPE_0803Pyruvate ferredoxin/flavodoxin oxidoreductase. (1178 aa)
fdaFructose-1,6-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (305 aa)
TPE_0985AMP-binding protein. (549 aa)
ptaPhosphate acetyltransferase. (335 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (209 aa)
TPE_1189Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family. (457 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (418 aa)
TPE_1458Formate acetyltransferase. (757 aa)
TPE_1459Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (240 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (369 aa)
TPE_1890Malate dehydrogenase. (498 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
rpiARibose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (243 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (695 aa)
TPE_20513-hydroxyacid dehydrogenase. (292 aa)
TPE_2214Phosphohexose mutase. (587 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (471 aa)
TPE_2364MutT/nudix; Belongs to the Nudix hydrolase family. (192 aa)
TPE_2574Phosphohexose mutase. (631 aa)
pfpDiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (563 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa)
pfkDiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (438 aa)
Your Current Organism:
Treponema pedis
NCBI taxonomy Id: 1291379
Other names: T. pedis str. T A4, Treponema pedis str. T A4
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