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csrA csrA deoD deoD TPE_2528 TPE_2528 xseA xseA TPE_0331 TPE_0331 TPE_0395 TPE_0395 TPE_0492 TPE_0492 rnhA rnhA deoC deoC TPE_0660 TPE_0660 TPE_0750 TPE_0750 TPE_0833 TPE_0833 yoeB yoeB TPE_0846 TPE_0846 TPE_0878 TPE_0878 TPE_0955 TPE_0955 pnp pnp dut dut rny rny TPE_1327 TPE_1327 TPE_1479 TPE_1479 TPE_1657 TPE_1657 TPE_1677 TPE_1677 xseB xseB TPE_1852 TPE_1852 rnhB rnhB cdd cdd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
csrACarbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (76 aa)
deoDPurine nucleoside phosphorylase. (233 aa)
TPE_2528Metal dependent phosphohydrolase. (416 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (395 aa)
TPE_0331RelE/StbE family addiction module toxin. (91 aa)
TPE_03955'-nucleotidase; Belongs to the 5'-nucleotidase family. (570 aa)
TPE_0492MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (242 aa)
rnhARibonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (150 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (216 aa)
TPE_0660Phosphatase/nucleotidase; Belongs to the 5'-nucleotidase family. (636 aa)
TPE_0750HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (198 aa)
TPE_0833MTA/SAH nucleosidase. (227 aa)
yoeBToxin of the YoeB-YefM toxin-antitoxin system. (87 aa)
TPE_0846Txe/YoeB family addiction module toxin. (87 aa)
TPE_0878Hypothetical protein. (62 aa)
TPE_0955Hypothetical protein. (116 aa)
pnpPolynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (697 aa)
dutDeoxyuridine 5'triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (146 aa)
rny2,3 cyclic-nucleotide 2-phosphodiesterase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (509 aa)
TPE_1327Hypothetical protein. (249 aa)
TPE_1479Metal dependent phosphohydrolase. (223 aa)
TPE_1657Hypothetical protein. (288 aa)
TPE_1677Nucleoside triphosphate pyrophosphohydrolase MazG. (285 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (78 aa)
TPE_1852Hypothetical protein. (86 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (199 aa)
cddCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (136 aa)
Your Current Organism:
Treponema pedis
NCBI taxonomy Id: 1291379
Other names: T. pedis str. T A4, Treponema pedis str. T A4
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