Your Input: | |
| | TPE_0750 | HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (198 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (506 aa) |
| | TPE_0764 | Hypothetical protein. (375 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (794 aa) |
| | lipA | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (266 aa) |
| | TPE_0770 | Putative transmembrane anti-sigma factor. (219 aa) |
| | cysS | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (495 aa) |
| | TPE_0783 | Adenosine deaminase. (299 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1107 aa) |
| | TPE_0797 | Iron-dependent transcriptional regulator. (142 aa) |
| | TPE_0803 | Pyruvate ferredoxin/flavodoxin oxidoreductase. (1178 aa) |
| | pyrB | Bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase regulatory subunit. (534 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (214 aa) |
| | TPE_0818 | Aminopeptidase 2. (432 aa) |
| | hppA | Vacuolar-type H(+)-translocatingpyrophosphatase; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily. (716 aa) |
| | TPE_0821 | Ferritin; Iron-storage protein. (161 aa) |
| | hflX | GTP-binding protein HflX, truncation; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (385 aa) |
| | thiD | Phosphomethylpyrimidine kinase. (269 aa) |
| | TPE_0826 | Hypothetical protein; Belongs to the LarC family. (454 aa) |
| | mtnN | GroES-like protein. (351 aa) |
| | TPE_0854 | SNF2 domain-containing protein. (1218 aa) |
| | murE-2 | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (535 aa) |
| | TPE_0903 | Transporter. (261 aa) |
| | TPE_0908 | DnaJ protein. (136 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (395 aa) |
| | TPE_0911 | Hypothetical protein. (1139 aa) |
| | TPE_0916 | NADH dehydrogenase (ubiquinone) 24 kDa subunit. (168 aa) |
| | TPE_0917 | Ferredoxin-like protein. (131 aa) |
| | TPE_0918 | NADH dehydrogenase (quinone). (586 aa) |
| | TPE_0919 | Hydrogenase, Fe-only. (594 aa) |
| | TPE_0924 | Neutrophil-activating protein A; Belongs to the Dps family. (143 aa) |
| | selD | Selenide, water dikinase. (257 aa) |
| | pnp | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (697 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase. (352 aa) |
| | trmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (470 aa) |
| | rimO | tRNA modifying protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (476 aa) |
| | TPE_0985 | AMP-binding protein. (549 aa) |
| | oadB | Biotin/lipoyl attachment domain-containingprotein. (119 aa) |
| | TPE_0987 | Hypothetical protein. (288 aa) |
| | TPE_1046 | Citrate lyase beta chain; Belongs to the HpcH/HpaI aldolase family. (294 aa) |
| | mamA | Methylaspartate mutase subunit S; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate). (141 aa) |
| | pepF | Oligoendopeptidase F. (612 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (175 aa) |
| | clpX | ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (411 aa) |
| | cheY | Chemotaxis protein CheY. (145 aa) |
| | gcp | DNA-binding/iron metalloprotein/AP endonuclease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (338 aa) |
| | TPE_1102 | NifU family protein. (75 aa) |
| | dut | Deoxyuridine 5'triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (146 aa) |
| | TPE_1107 | ferredoxin-NADP(+) reductase subunit alpha. (278 aa) |
| | TPE_1114 | Aldehyde oxidase and xanthine dehydrogenase. (695 aa) |
| | TPE_1115 | Iron-sulfur cluster-binding protein. (159 aa) |
| | TPE_1126 | Heavy metal translocating P-type ATPase. (699 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (209 aa) |
| | cbiK | Cobalt chelatase. (271 aa) |
| | TPE_1176 | Methylaspartate ammonia-lyase. (412 aa) |
| | TPE_1233 | FKBP-type peptidyl-prolyl cis-trans isomerase. (182 aa) |
| | TPE_1240 | Ferredoxin like protein. (94 aa) |
| | TPE_1305 | Radical SAM superfamily protein. (404 aa) |
| | TPE_1306 | Radical SAM protein. (372 aa) |
| | TPE_1308 | Radical SAM domain-containing protein. (448 aa) |
| | TPE_1312 | PilT. (81 aa) |
| | TPE_1324 | TfoX. (57 aa) |
| | TPE_1371 | Radical SAM domain-containing protein. (432 aa) |
| | TPE_1384 | Hydrolase, NUDIX family. (87 aa) |
| | TPE_1406 | Hypothetical protein. (197 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (376 aa) |
| | TPE_1441 | Phosphoesterase. (221 aa) |
| | TPE_1459 | Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (240 aa) |
| | TPE_1462 | Hypothetical protein. (226 aa) |
| | TPE_1489 | Radical SAM domain protein. (285 aa) |
| | TPE_1537 | Hypothetical protein. (227 aa) |
| | TPE_1538 | Rubrerythrin. (191 aa) |
| | TPE_1540 | VanZ family protein. (133 aa) |
| | TPE_1548 | Hypothetical protein. (150 aa) |
| | TPE_1646 | Oxygen-independent coproporphyrinogen III oxidase. (426 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (436 aa) |
| | ddl | D-alanyl-alanine synthetase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (370 aa) |
| | TPE_1659 | Folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. (453 aa) |
| | TPE_1665 | ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 9 family. (319 aa) |
| | folP | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (325 aa) |
| | TPE_1668 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase. (581 aa) |
| | TPE_1674 | Galactokinase; Belongs to the GHMP kinase family. (407 aa) |
| | TPE_1757 | Iron-sulfur binding reductase. (312 aa) |
| | TPE_1766 | Hypothetical protein. (313 aa) |
| | pcaC | Radical SAM domain-containing protein. (329 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (599 aa) |
| | TPE_1802 | Hemerythrin-like protein. (138 aa) |
| | TPE_1815 | Aminopeptidase 1. (470 aa) |
| | TPE_1817 | Radical SAM protein. (248 aa) |
| | ybeY | Metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (156 aa) |
| | TPE_1864 | Metallophosphoesterase. (263 aa) |
| | pepT | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (410 aa) |
| | ligA | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (643 aa) |
| | rnfB | Ferredoxin; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (285 aa) |
| | TPE_1889 | Peptidase M42 family protein. (364 aa) |
| | TPE_1890 | Malate dehydrogenase. (498 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa) |
| | rlmN | Radical SAM protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (351 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa) |
| | uvrA | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (957 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (199 aa) |
| | yjeQ | GTPase YjeQ; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (308 aa) |
| | TPE_1963 | Iron-containing alcohol dehydrogenase. (395 aa) |
| | TPE_1967 | UVR protein. (167 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (483 aa) |
| | TPE_1996 | Hypothetical protein. (199 aa) |
| | dnaJ-2 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (379 aa) |
| | TPE_2021 | Hypothetical protein. (378 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (695 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (263 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase. (441 aa) |
| | TPE_2044 | Fumarate hydratase. (281 aa) |
| | nadK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (280 aa) |
| | nrdR | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (161 aa) |
| | TPE_2065 | Radical SAM protein. (269 aa) |
| | TPE_2099 | Deoxycytidylate deaminase. (168 aa) |
| | hslV | ATP-dependent protease peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. (178 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (726 aa) |
| | TPE_2126 | Hypothetical protein. (286 aa) |
| | TPE_2146 | Hemerythrin. (148 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (235 aa) |
| | TPE_2150 | Membrane-associated zinc metalloprotease. (450 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (371 aa) |
| | uppS | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (216 aa) |
| | citE | Citrate lyase subunit beta; Belongs to the HpcH/HpaI aldolase family. (283 aa) |
| | TPE_2193 | C4 zinc finger. (119 aa) |
| | TPE_2195 | DnaJ protein. (188 aa) |
| | acpS | holo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (124 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (647 aa) |
| | TPE_2211 | Hypothetical protein. (149 aa) |
| | TPE_2214 | Phosphohexose mutase. (587 aa) |
| | cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (136 aa) |
| | TPE_2227 | Hypothetical protein. (521 aa) |
| | ispG-2 | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (395 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (599 aa) |
| | pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (471 aa) |
| | secA | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (916 aa) |
| | TPE_2291 | Hypothetical protein. (399 aa) |
| | TPE_2297 | ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family. (383 aa) |
| | TPE_2298 | RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (398 aa) |
| | TPE_2302 | Hypothetical protein. (199 aa) |
| | TPE_2309 | Fe-hydrogenase. (598 aa) |
| | miaB | (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (465 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (462 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (245 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (657 aa) |
| | TPE_2352 | DNA polymerase. (300 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (209 aa) |
| | TPE_2357 | Ferredoxin, 2(4Fe-4S). (58 aa) |
| | rpmE | 50S ribosomal protein L31; Binds the 23S rRNA. (67 aa) |
| | cadA | Cadmium-translocating P-type ATPase. (750 aa) |
| | radC | DNA repair protein RadC; Belongs to the UPF0758 family. (242 aa) |
| | TPE_2393 | Iron-sulfur cluster-binding protein. (310 aa) |
| | TPE_2414 | TfoX. (48 aa) |
| | TPE_2418 | Hypothetical protein. (127 aa) |
| | TPE_2432 | Hypothetical protein. (215 aa) |
| | rnfC | Putative NADH dehydrogenase (ubiquinone),subunit RnfC. (427 aa) |
| | TPE_2466 | Hypothetical protein. (421 aa) |
| | TPE_2467 | Cobalamin synthesis protein P47K. (242 aa) |
| | nif3 | NGG1p interacting factor protein. (273 aa) |
| | TPE_2487 | CarB. (600 aa) |
| | dfp | Fused 4'-phosphopantothenoylcysteinedecarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (396 aa) |
| | TPE_2495 | LemA. (202 aa) |
| | ispH | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (315 aa) |
| | ptsI | Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (584 aa) |
| | TPE_2574 | Phosphohexose mutase. (631 aa) |
| | selD-2 | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (344 aa) |
| | map | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (248 aa) |
| | TPE_2592 | Heat shock protein DnaJ domain-containingprotein. (274 aa) |
| | rsgA | GTPase YjeQ; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (364 aa) |
| | sH | Cell division protein sH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (675 aa) |
| | pfp | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (563 aa) |
| | recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (209 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (945 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (436 aa) |
| | def | Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (161 aa) |
| | TPE_2753 | Iron-dependent transcriptional regulator. (221 aa) |
| | troA | Zinc ABC transporter periplasmic zinc-binding protein; Belongs to the bacterial solute-binding protein 9 family. (313 aa) |
| | TPE_2765 | Sir2 family transcriptional regulator. (252 aa) |
| | pfk | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (438 aa) |
| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (308 aa) |
| | gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (638 aa) |
| | TPE_0008 | Radical SAM protein. (345 aa) |
| | TPE_0035 | Diaminopimelate aminotransferase. (407 aa) |
| | TPE_0041 | Pyruvate phosphate dikinase. (976 aa) |
| | TPE_0071 | Desulfoferrodoxin/neelaredoxin. (128 aa) |
| | TPE_0158 | Membrane protein. (379 aa) |
| | queH | Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (216 aa) |
| | ptmE | LmbE-like protein. (223 aa) |
| | rfbA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (291 aa) |
| | sdhA | L-serine dehydratase, iron-sulfur-dependent subunit alpha. (292 aa) |
| | sdhB | L-serine dehydratase, iron-sulfur-dependent subunit beta. (220 aa) |
| | TPE_0226 | MiaB-like tRNA modifying enzyme. (458 aa) |
| | mglB | Galactose/glucose-binding lipoprotein. (400 aa) |
| | TPE_0248 | ABC transporter periplasmic substrate-binding protein. (372 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (433 aa) |
| | TPE_0260 | Hypothetical protein. (97 aa) |
| | TPE_0262 | Hemerythrin hhE cation binding domain-containingprotein. (185 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (550 aa) |
| | ppdK | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (939 aa) |
| | TPE_0269 | L-fuculose phosphate aldolase. (366 aa) |
| | TPE_0281 | Lipoprotein. (327 aa) |
| | TPE_0284 | Aldehyde oxidase and xanthine dehydrogenasemolybdopterin binding protein. (114 aa) |
| | TPE_0301 | Thiamine ABC transporter thiamine-binding protein. (338 aa) |
| | guaB | Inosine 5-monophosphate dehydrogenase. (504 aa) |
| | TPE_0336 | Iron-containing alcohol dehydrogenase. (384 aa) |
| | TPE_0366 | Dihydroorotase. (351 aa) |
| | TPE_0376 | Hypothetical protein. (151 aa) |
| | TPE_0377 | FeoA. (75 aa) |
| | feoA | Ferrous iron transporter A. (75 aa) |
| | hbpB | Hemin-binding protein B. (395 aa) |
| | recO | Recombination protein O. (264 aa) |
| | TPE_0395 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (570 aa) |
| | ruvC | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (171 aa) |
| | TPE_0403 | M16 family peptidase. (1003 aa) |
| | hprK | HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (329 aa) |
| | TPE_0417 | Copper-translocating P-type ATPase. (851 aa) |
| | obgE | GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (418 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1424 aa) |
| | TPE_0451 | Hypothetical protein. (193 aa) |
| | TPE_0456 | Aminopeptidase. (409 aa) |
| | TPE_0458 | NifU family protein. (140 aa) |
| | thrS | threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (564 aa) |
| | yhfE | Peptidase M42 family protein. (379 aa) |
| | TPE_0475 | Hypothetical protein. (193 aa) |
| | pheT | phenylalanyl-tRNA synthetase subunit beta. (580 aa) |
| | TPE_0485 | Ser/Thr protein phosphatase family protein. (275 aa) |
| | TPE_0491 | 3-dehydroquinate synthase. (353 aa) |
| | TPE_0507 | Iron-containing alcohol dehydrogenase. (383 aa) |
| | TPE_0529 | Metallo-beta-lactamase. (213 aa) |
| | rnhA | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (150 aa) |
| | kamA | Lysine 2,3-aminomutase. (360 aa) |
| | sodC | Copper/zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (144 aa) |
| | TPE_0564 | Hypothetical protein. (194 aa) |
| | TPE_0568 | Glycosyl transferase, group 4. (360 aa) |
| | TPE_0576 | Hypothetical protein. (254 aa) |
| | nrdF | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (351 aa) |
| | TPE_0593 | Peptidase M16 domain-containing protein. (491 aa) |
| | TPE_0594 | Peptidase M16 domain-containing protein. (491 aa) |
| | prs | Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (417 aa) |
| | TPE_0614 | Hypothetical protein. (434 aa) |
| | TPE_0617 | Oligoendopeptidase F. (576 aa) |
| | TPE_0654 | Radical SAM domain-containing protein. (318 aa) |
| | galK | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (396 aa) |
| | engB | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (211 aa) |
| | pheS | phenylalanyl-tRNA synthetase subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (515 aa) |
| | cas2 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (112 aa) |
| | cas1 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (295 aa) |
| | csn1 | Csn1 family CRISPR-associated protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans- encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this p [...] (1282 aa) |
| | TPE_0697 | Hypothetical protein. (205 aa) |
| | pepA | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (476 aa) |
| | TPE_0715 | Heme biosynthesis protein related protein. (432 aa) |
| | mgtE | Magnesium transporter; Acts as a magnesium transporter. (452 aa) |
| | hutI | Imidazolonepropionase. (405 aa) |
| | TPE_0728 | Hypothetical protein. (305 aa) |
