(40 nodes) Sarcoplasmic reticulum network (Amazona aestiva)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AAES_00083	Peptidylprolyl isomerase. (79 aa)
	AAES_155398	Protein PBDC1-like protein. (90 aa)
	AAES_166103	Junctophilin-2-like protein. (169 aa)
	AAES_132601	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1072 aa)
	AAES_119655	Uncharacterized protein. (2601 aa)
	AAES_111183	Fibronectin type III and SPRY domain-containing protein 2. (786 aa)
	AAES_98939	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (761 aa)
	AAES_81296	Triadin. (509 aa)
	AAES_66385	Calcium homeostasis endoplasmic reticulum protein. (715 aa)
	AAES_59562	Mesencephalic astrocyte-derived neurotrophic factor. (162 aa)
	AAES_56050	Uncharacterized protein. (972 aa)
	AAES_49925	Receptor expression-enhancing protein. (189 aa)
	AAES_43097	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (407 aa)
	AAES_156304	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein. (795 aa)
	AAES_117045	Prolyl 3-hydroxylase 2. (697 aa)
	AAES_52459	Coiled-coil domain-containing protein 78. (386 aa)
	AAES_38931	Uncharacterized protein. (4375 aa)
	AAES_38717	Uncharacterized protein. (999 aa)
	AAES_38879	Thrombospondin-1. (1176 aa)
	AAES_38727	A-kinase anchor protein 6. (1435 aa)
	AAES_166106	Uncharacterized protein. (142 aa)
	AAES_139134	HCLS1-associated protein X-1. (269 aa)
	AAES_96021	Dehydrogenase/reductase SDR family member 7C-like protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (320 aa)
	AAES_25414	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein-like protein. (646 aa)
	AAES_56009	Inositol 1,4,5-trisphosphate receptor type 1-like protein. (1744 aa)
	AAES_51822	Uncharacterized protein. (192 aa)
	AAES_19376	Ion_trans domain-containing protein. (526 aa)
	AAES_10736	Endoplasmin. (794 aa)
	AAES_09980	Protein O-mannosyl-transferase 1. (725 aa)
	AAES_12912	Dexamethasone-induced Ras-related protein 1. (278 aa)
	AAES_14884	Sarcalumenin isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (484 aa)
	AAES_166112	Junctophilin 2. (388 aa)
	AAES_66363	Trimeric intracellular cation channel type A. (297 aa)
	AAES_56864	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa)
	STIM1	Stromal interaction molecule 1. (405 aa)
	AAES_32134	Ion_trans domain-containing protein. (239 aa)
	AAES_32080	Inositol 1,4,5-trisphosphate receptor type 3. (2462 aa)
	AAES_24119	Junctophilin-1 isoform X1. (561 aa)
	AAES_19388	Inositol 1,4,5-trisphosphate receptor type 2 isoform X2. (2228 aa)
	AAES_10227	EF-hand domain-containing protein. (1897 aa)

Your Current Organism:

Amazona aestiva

NCBI taxonomy Id: 12930
Other names: A. aestiva, blue-fronted amazon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAES_00083	AAES_10227	A0A0Q3NYD9	A0A0Q3X991	Peptidylprolyl isomerase.	EF-hand domain-containing protein.	0.918
AAES_00083	AAES_10736	A0A0Q3NYD9	A0A0Q3U2T7	Peptidylprolyl isomerase.	Endoplasmin.	0.692
AAES_00083	AAES_119655	A0A0Q3NYD9	A0A0Q3M5Z0	Peptidylprolyl isomerase.	Uncharacterized protein.	0.918
AAES_00083	AAES_38931	A0A0Q3NYD9	A0A0Q3PWY1	Peptidylprolyl isomerase.	Uncharacterized protein.	0.918
AAES_00083	AAES_43097	A0A0Q3NYD9	A0A0Q3MRE3	Peptidylprolyl isomerase.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.517
AAES_00083	AAES_81296	A0A0Q3NYD9	A0A0Q3MFU5	Peptidylprolyl isomerase.	Triadin.	0.760
AAES_10227	AAES_00083	A0A0Q3X991	A0A0Q3NYD9	EF-hand domain-containing protein.	Peptidylprolyl isomerase.	0.918
AAES_10227	AAES_119655	A0A0Q3X991	A0A0Q3M5Z0	EF-hand domain-containing protein.	Uncharacterized protein.	0.943
AAES_10227	AAES_132601	A0A0Q3X991	A0A0Q3M202	EF-hand domain-containing protein.	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.427
AAES_10227	AAES_38717	A0A0Q3X991	A0A0Q3PX36	EF-hand domain-containing protein.	Uncharacterized protein.	0.402
AAES_10227	AAES_38727	A0A0Q3X991	A0A0Q3QBY6	EF-hand domain-containing protein.	A-kinase anchor protein 6.	0.402
AAES_10227	AAES_38931	A0A0Q3X991	A0A0Q3PWY1	EF-hand domain-containing protein.	Uncharacterized protein.	0.799
AAES_10227	AAES_43097	A0A0Q3X991	A0A0Q3MRE3	EF-hand domain-containing protein.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.879
AAES_10227	AAES_51822	A0A0Q3X991	A0A0Q3TTR0	EF-hand domain-containing protein.	Uncharacterized protein.	0.416
AAES_10227	AAES_56864	A0A0Q3X991	A0A0Q3UTA8	EF-hand domain-containing protein.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.416
AAES_10227	AAES_81296	A0A0Q3X991	A0A0Q3MFU5	EF-hand domain-containing protein.	Triadin.	0.876
AAES_10736	AAES_00083	A0A0Q3U2T7	A0A0Q3NYD9	Endoplasmin.	Peptidylprolyl isomerase.	0.692
AAES_10736	AAES_12912	A0A0Q3U2T7	A0A0Q3U691	Endoplasmin.	Dexamethasone-induced Ras-related protein 1.	0.500
AAES_10736	AAES_59562	A0A0Q3U2T7	A0A0Q3MLT2	Endoplasmin.	Mesencephalic astrocyte-derived neurotrophic factor.	0.591
AAES_111183	AAES_81296	A0A0Q3M8I5	A0A0Q3MFU5	Fibronectin type III and SPRY domain-containing protein 2.	Triadin.	0.403