(70 nodes) Regulation of mRNA splicing, via spliceosome network (Amazona aestiva)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

gene neighborhood

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co-expression

protein homology

Your Input:
	AAES_130214	Transformer-2 protein beta isoform X1. (288 aa)
	AAES_166442	Poly(U)-binding-splicing factor PUF60 isoform X4. (530 aa)
	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3. (138 aa)
	AAES_148507	Putative RNA-binding protein 15. (768 aa)
	AAES_148577	Serine/arginine-rich splicing factor 3. (164 aa)
	AAES_147420	Protein SON isoform X5. (3809 aa)
	AAES_140203	Muscleblind-like protein 3 isoform X1. (371 aa)
	AAES_242965	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (410 aa)
	AAES_123297	Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (153 aa)
	AAES_106663	WD40 repeat-containing protein SMU1. (513 aa)
	AAES_109893	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (417 aa)
	AAES_96247	Serine/arginine-rich splicing factor 2. (221 aa)
	AAES_91053	Eukaryotic initiation factor 4A-III-like protein; Belongs to the DEAD box helicase family. (433 aa)
	AAES_95045	Muscleblind-like protein 1 isoform X3. (603 aa)
	RBM11	RNA binding motif protein 11. (158 aa)
	AAES_85351	Fragile X mental retardation syndrome-related protein 1 isoform X2. (650 aa)
	AAES_79396	RNA-binding protein 38. (81 aa)
	AAES_79486	Pre-mRNA-splicing regulator WTAP-like isoform X1. (443 aa)
	AAES_71121	Uncharacterized protein. (421 aa)
	AAES_70429	Cold-inducible RNA-binding protein isoform X2. (174 aa)
	AAES_59470	G-patch domain-containing protein. (1303 aa)
	AAES_51544	SNW domain-containing protein 1. (626 aa)
	AAES_49400	CUGBP Elav-like family member 4. (415 aa)
	AAES_48052	RNA-binding protein 5 isoform X1. (847 aa)
	AAES_41065	Zinc finger CCCH domain-containing protein 10. (215 aa)
	AAES_157831	Splicing factor, suppressor of white-apricot isoform X1. (774 aa)
	AAES_146067	Serine/arginine repetitive matrix protein 1. (1028 aa)
	AAES_136496	Putative ATP-dependent RNA helicase DDX17. (906 aa)
	AAES_119954	Uncharacterized protein. (938 aa)
	AAES_163988	CUGBP Elav-like family member 2-like protein. (129 aa)
	AAES_113909	CUGBP Elav-like family member 1 isoform X2. (446 aa)
	AAES_223555	YTH domain-containing protein 1-like isoform X2. (656 aa)
	AAES_145162	RNA-binding motif protein, X chromosome isoform X1. (425 aa)
	AAES_96998	RRM domain-containing protein. (155 aa)
	AAES_217603	Uncharacterized protein. (240 aa)
	AAES_132753	KH domain-containing, RNA-binding, signal transduction-associated protein 2. (360 aa)
	AAES_76748	RNA-binding protein 25 isoform X2. (791 aa)
	AAES_112054	RNA-binding protein 7. (264 aa)
	AAES_49387	CUGBP Elav-like family member 4. (143 aa)
	AAES_47615	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (108 aa)
	AAES_97004	RNA-binding protein 20. (567 aa)
	AAES_34886	Peptidase S59 domain-containing protein. (1264 aa)
	AAES_82870	RNA binding protein fox-1 3 isoform X2. (305 aa)
	AAES_70861	CUGBP Elav-like family member 5 isoform X2. (451 aa)
	AAES_59560	Putative RNA-binding protein 15B. (917 aa)
	AAES_166512	RNA-binding protein Nova-1 isoform X3. (467 aa)
	AAES_125212	Protein quaking isoform X3. (314 aa)
	AAES_224029	Fragile X mental retardation protein 1 B. (844 aa)
	AAES_70374	DAZ-associated protein 1. (433 aa)
	AAES_70644	Polypyrimidine tract-binding protein 1. (637 aa)
	AAES_160005	KH domain-containing, RNA-binding, signal transduction-associated protein 3 isoformX2. (241 aa)
	AAES_116094	Transformer-2 protein alpha isoform X1. (277 aa)
	AAES_105824	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (558 aa)
	AAES_96232	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6. (443 aa)
	AAES_66781	RNA-binding protein 24 isoform X1. (225 aa)
	AAES_20162	Uncharacterized protein. (790 aa)
	AAES_58501	RNA-binding protein 38. (197 aa)
	AAES_146278	CUGBP Elav-like family member 2. (360 aa)
	AAES_112712	Nucleolin. (615 aa)
	AAES_96996	Uncharacterized protein. (350 aa)
	AAES_77250	Putative ATP-dependent RNA helicase DDX5 isoform X1; Belongs to the DEAD box helicase family. (603 aa)
	AAES_35262	RNA-binding protein 39 isoform X18. (522 aa)
	AAES_30529	Heterogeneous nuclear ribonucleoprotein K isoform X2. (431 aa)
	AAES_26365	Pre-mRNA-processing factor 19. (444 aa)
	AAES_27045	Myogenic factor. (296 aa)
	AAES_18917	La-related protein 7. (496 aa)
	AAES_22733	Muscleblind-like protein 2 isoform X1. (446 aa)
	SRRM4	Serine/arginine repetitive matrix 4. (502 aa)
	AAES_15848	Thyroid hormone receptor-associated protein 3. (970 aa)
	AAES_05106	Ribonucleoprotein PTB-binding 2. (591 aa)

Your Current Organism:

Amazona aestiva

NCBI taxonomy Id: 12930
Other names: A. aestiva, blue-fronted amazon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAES_05106	AAES_109893	A0A0Q3X9T9	A0A0Q3M9K1	Ribonucleoprotein PTB-binding 2.	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events.	0.414
AAES_05106	AAES_116094	A0A0Q3X9T9	A0A0Q3TD27	Ribonucleoprotein PTB-binding 2.	Transformer-2 protein alpha isoform X1.	0.480
AAES_05106	AAES_119954	A0A0Q3X9T9	A0A0Q3PAH7	Ribonucleoprotein PTB-binding 2.	Uncharacterized protein.	0.541
AAES_05106	AAES_130214	A0A0Q3X9T9	A0A0Q3P7V5	Ribonucleoprotein PTB-binding 2.	Transformer-2 protein beta isoform X1.	0.480
AAES_05106	AAES_145162	A0A0Q3X9T9	A0A0Q3PGF7	Ribonucleoprotein PTB-binding 2.	RNA-binding motif protein, X chromosome isoform X1.	0.480
AAES_05106	AAES_148577	A0A0Q3X9T9	A0A0Q3LXK8	Ribonucleoprotein PTB-binding 2.	Serine/arginine-rich splicing factor 3.	0.433
AAES_05106	AAES_18917	A0A0Q3X9T9	A0A0Q3X7W3	Ribonucleoprotein PTB-binding 2.	La-related protein 7.	0.457
AAES_05106	AAES_217603	A0A0Q3X9T9	A0A0Q3PID3	Ribonucleoprotein PTB-binding 2.	Uncharacterized protein.	0.427
AAES_05106	AAES_242965	A0A0Q3X9T9	A0A0Q3M1A6	Ribonucleoprotein PTB-binding 2.	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events.	0.427
AAES_05106	AAES_30529	A0A0Q3X9T9	A0A0Q3VX82	Ribonucleoprotein PTB-binding 2.	Heterogeneous nuclear ribonucleoprotein K isoform X2.	0.693
AAES_05106	AAES_48052	A0A0Q3X9T9	A0A0Q3MQ02	Ribonucleoprotein PTB-binding 2.	RNA-binding protein 5 isoform X1.	0.437
AAES_05106	AAES_59470	A0A0Q3X9T9	A0A0Q3MLP8	Ribonucleoprotein PTB-binding 2.	G-patch domain-containing protein.	0.437
AAES_05106	AAES_70429	A0A0Q3X9T9	A0A0Q3MJ20	Ribonucleoprotein PTB-binding 2.	Cold-inducible RNA-binding protein isoform X2.	0.480
AAES_05106	AAES_70644	A0A0Q3X9T9	A0A0Q3RAV0	Ribonucleoprotein PTB-binding 2.	Polypyrimidine tract-binding protein 1.	0.541
AAES_05106	AAES_82870	A0A0Q3X9T9	A0A0Q3PZ38	Ribonucleoprotein PTB-binding 2.	RNA binding protein fox-1 3 isoform X2.	0.457
AAES_05106	AAES_96247	A0A0Q3X9T9	A0A0Q3MCV8	Ribonucleoprotein PTB-binding 2.	Serine/arginine-rich splicing factor 2.	0.507
AAES_105824	AAES_145162	A0A0Q3TFH3	A0A0Q3PGF7	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]	RNA-binding motif protein, X chromosome isoform X1.	0.405
AAES_105824	AAES_223555	A0A0Q3TFH3	A0A0Q3PG14	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]	YTH domain-containing protein 1-like isoform X2.	0.480
AAES_105824	AAES_79486	A0A0Q3TFH3	A0A0Q3MGH5	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]	Pre-mRNA-splicing regulator WTAP-like isoform X1.	0.534
AAES_106663	AAES_136496	A0A0Q3M8Z4	A0A0Q3P6P1	WD40 repeat-containing protein SMU1.	Putative ATP-dependent RNA helicase DDX17.	0.671