STRINGSTRING
AGN25519.1 AGN25519.1 AGN25520.1 AGN25520.1 AGN25521.1 AGN25521.1 AGN25522.1 AGN25522.1 AGN25808.1 AGN25808.1 AGN26397.1 AGN26397.1 AGN26398.1 AGN26398.1 AGN26399.1 AGN26399.1 AGN26400.1 AGN26400.1 AGN26401.1 AGN26401.1 AGN26501.1 AGN26501.1 thiE thiE thiM thiM AGN26691.1 AGN26691.1 AGY50197.1 AGY50197.1 AGN26709.1 AGN26709.1 AGN26710.1 AGN26710.1 AGN26711.1 AGN26711.1 AGN26716.1 AGN26716.1 thiM-2 thiM-2 thiE-2 thiE-2 AGN27034.1 AGN27034.1 thiC thiC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGN25519.1FAD dependent oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating). (427 aa)
AGN25520.1Rhodanese domain-containing protein; COG0607 Rhodanese-related sulfurtransferase. (109 aa)
AGN25521.1Cadmium-zinc resistance protein CzrB; COG0053 Predicted Co/Zn/Cd cation transporters. (291 aa)
AGN25522.1Hypothetical protein. (401 aa)
AGN25808.1COG1977 Molybdopterin converting factor, small subunit. (93 aa)
AGN26397.1ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components. (370 aa)
AGN26398.1COG1177 ABC-type spermidine/putrescine transport system, permease component II. (264 aa)
AGN26399.1COG4208 ABC-type sulfate transport system, permease component. (284 aa)
AGN26400.1Hypothetical protein; COG4134 ABC-type uncharacterized transport system, periplasmic component. (540 aa)
AGN26401.1Radical SAM domain and peroxiredoxin domain containing protein; COG0502 Biotin synthase and related enzymes. (496 aa)
AGN26501.1COG2104 Sulfur transfer protein involved in thiamine biosynthesis. (66 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (210 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (267 aa)
AGN26691.1Hypothetical protein; COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (270 aa)
AGY50197.1Thiamine biosynthesis protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. (239 aa)
AGN26709.1PRC-barrel domain containing protein; COG1086 Predicted nucleoside-diphosphate sugar epimerases. (174 aa)
AGN26710.1Cytosolic Fe-S cluster assembling factor NBP35; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (276 aa)
AGN26711.1Hypothetical protein; COG0640 Predicted transcriptional regulators. (115 aa)
AGN26716.1Hypothetical protein; COG0428 Predicted divalent heavy-metal cations transporter. (267 aa)
thiM-2Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (272 aa)
thiE-2Thiamine-phosphate pyrophosphorylase ThiE2; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (211 aa)
AGN27034.1Hypothetical protein; COG0637 Predicted phosphatase/phosphohexomutase. (230 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (424 aa)
Your Current Organism:
Methanomassiliicoccus intestinalis
NCBI taxonomy Id: 1295009
Other names: C. Methanomassiliicoccus intestinalis Issoire-Mx1, Candidatus Methanomassiliicoccus intestinalis Issoire-Mx1
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