STRINGSTRING
AGN25451.1 AGN25451.1 AGN25452.1 AGN25452.1 AGN25453.1 AGN25453.1 AGN25454.1 AGN25454.1 AGN25455.1 AGN25455.1 AGN25456.1 AGN25456.1 AGN25510.1 AGN25510.1 AGY50151.1 AGY50151.1 AGN25575.1 AGN25575.1 AGN25680.1 AGN25680.1 AGN25681.1 AGN25681.1 AGN25710.1 AGN25710.1 AGN25711.1 AGN25711.1 AGN25718.1 AGN25718.1 AGN25719.1 AGN25719.1 AGN25720.1 AGN25720.1 AGN25721.1 AGN25721.1 AGN25769.1 AGN25769.1 AGY50158.1 AGY50158.1 AGN25842.1 AGN25842.1 AGN25843.1 AGN25843.1 AGN25844.1 AGN25844.1 AGN25863.1 AGN25863.1 AGY50159.1 AGY50159.1 AGN25865.1 AGN25865.1 AGN25866.1 AGN25866.1 AGY50160.1 AGY50160.1 AGN25881.1 AGN25881.1 AGN25885.1 AGN25885.1 AGY50161.1 AGY50161.1 AGN25887.1 AGN25887.1 AGN25900.1 AGN25900.1 AGN25916.1 AGN25916.1 AGN25966.1 AGN25966.1 AGY50164.1 AGY50164.1 AGN25985.1 AGN25985.1 AGN26005.1 AGN26005.1 AGN26006.1 AGN26006.1 AGN26007.1 AGN26007.1 AGN26008.1 AGN26008.1 AGN26009.1 AGN26009.1 AGN26010.1 AGN26010.1 AGN26011.1 AGN26011.1 AGN26012.1 AGN26012.1 AGN26013.1 AGN26013.1 AGN26014.1 AGN26014.1 AGN26015.1 AGN26015.1 AGN26087.1 AGN26087.1 AGN26195.1 AGN26195.1 AGN26198.1 AGN26198.1 hypA hypA AGY50174.1 AGY50174.1 AGN26247.1 AGN26247.1 AGN26248.1 AGN26248.1 AGN26249.1 AGN26249.1 AGN26250.1 AGN26250.1 AGN26251.1 AGN26251.1 AGN26252.1 AGN26252.1 AGN26253.1 AGN26253.1 AGY50175.1 AGY50175.1 AGN26255.1 AGN26255.1 AGY50176.1 AGY50176.1 AGN26256.1 AGN26256.1 AGN26257.1 AGN26257.1 AGY50177.1 AGY50177.1 AGY50178.1 AGY50178.1 AGN26262.1 AGN26262.1 AGN26293.1 AGN26293.1 AGN26402.1 AGN26402.1 AGN26408.1 AGN26408.1 AGN26462.1 AGN26462.1 AGN26653.1 AGN26653.1 AGY50193.1 AGY50193.1 AGN26655.1 AGN26655.1 queC queC queE queE AGN26679.1 AGN26679.1 AGN26744.1 AGN26744.1 AGN26870.1 AGN26870.1 AGN26871.1 AGN26871.1 AGN26872.1 AGN26872.1 AGN26873.1 AGN26873.1 AGN26874.1 AGN26874.1 AGN26875.1 AGN26875.1 AGN26876.1 AGN26876.1 AGY50213.1 AGY50213.1 AGN26878.1 AGN26878.1 AGN26882.1 AGN26882.1 AGN26883.1 AGN26883.1 AGN26884.1 AGN26884.1 AGY50225.1 AGY50225.1 AGN27178.1 AGN27178.1 AGN27180.1 AGN27180.1 AGN27181.1 AGN27181.1 AGN27182.1 AGN27182.1 AGN27184.1 AGN27184.1 AGN27185.1 AGN27185.1 AGN27186.1 AGN27186.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGN25451.1FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG1148 Heterodisulfide reductase, subunit A and related polyferredoxins. (333 aa)
AGN25452.14Fe-4S ferredoxin; COG1148 Heterodisulfide reductase, subunit A and related polyferredoxins. (359 aa)
AGN25453.1COG1908 Coenzyme F420-reducing hydrogenase, delta subunit. (130 aa)
AGN25454.1Hypothetical protein. (233 aa)
AGN25455.1COG0685 5,10-methylenetetrahydrofolate reductase. (298 aa)
AGN25456.1Methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; COG1410 Methionine synthase I, cobalamin-binding domain. (258 aa)
AGN25510.1CoB--CoM heterodisulfide reductase; COG0247 Fe-S oxidoreductase. (393 aa)
AGY50151.1Hydrogenase expression/formation protein HypE; COG0309 Hydrogenase maturation factor. (348 aa)
AGN25575.1Hydrogenase nickel incorporation protein hypB; COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase. (218 aa)
AGN25680.1Methanol methyltransferase corrinoid protein; COG1410 Methionine synthase I, cobalamin-binding domain. (288 aa)
AGN25681.1Methanol:corrinoid methyltransferase. (467 aa)
AGN25710.1Methanol methyltransferase corrinoid protein; COG5012 Predicted cobalamin binding protein. (262 aa)
AGN25711.1Methanol:corrinoid methyltransferase. (467 aa)
AGN25718.1COG2048 Heterodisulfide reductase, subunit B. (273 aa)
AGN25719.1COG1150 Heterodisulfide reductase, subunit C. (170 aa)
AGN25720.1Hypothetical protein; COG0583 Transcriptional regulator. (271 aa)
AGN25721.1COG0680 Ni,Fe-hydrogenase maturation factor. (151 aa)
AGN25769.1[NiFe] hydrogenase metallocenter assembly protein HypC; COG0298 Hydrogenase maturation factor. (78 aa)
AGY50158.15-methyltetrahydrofolate--homocysteine methyltransferase; COG5012 Predicted cobalamin binding protein. (216 aa)
AGN25842.1Hypothetical protein; COG0407 Uroporphyrinogen-III decarboxylase. (361 aa)
AGN25843.1Hypothetical protein. (104 aa)
AGN25844.1Hydantoinase/oxoprolinase; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. (669 aa)
AGN25863.1Heterodisulfide reductase, subunit A-related polyferredoxin; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (1007 aa)
AGY50159.1COG1908 Coenzyme F420-reducing hydrogenase, delta subunit. (153 aa)
AGN25865.1COG1941 Coenzyme F420-reducing hydrogenase, gamma subunit. (336 aa)
AGN25866.1COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit. (504 aa)
AGY50160.1Hypothetical protein. (210 aa)
AGN25881.1COG2061 ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. (164 aa)
AGN25885.1COG4022 Uncharacterized protein conserved in archaea. (267 aa)
AGY50161.1Uroporphyrinogen-III decarboxylase. (332 aa)
AGN25887.1Uroporphyrinogen-III decarboxylase. (371 aa)
AGN25900.1Methyl-viologen-reducing hydrogenase subunit delta; COG1148 Heterodisulfide reductase, subunit A and related polyferredoxins. (364 aa)
AGN25916.1Hypothetical protein; COG0247 Fe-S oxidoreductase. (288 aa)
AGN25966.1Methanol:corrinoid methyltransferase; COG2115 Xylose isomerase. (469 aa)
AGY50164.1Methanol methyltransferase corrinoid protein; COG5012 Predicted cobalamin binding protein. (250 aa)
AGN25985.1COG0068 Hydrogenase maturation factor. (692 aa)
AGN26005.1Methyl coenzyme M reductase system, component A2; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase. (539 aa)
AGN26006.1COG4056 Methyl coenzyme M reductase, subunit C. (200 aa)
AGN26007.1Hypothetical protein. (187 aa)
AGN26008.1Hypothetical protein; COG4070 Predicted peptidyl-prolyl cis-trans isomerase (rotamase), cyclophilin family; Belongs to the UPF0288 family. (532 aa)
AGN26009.1COG4029 Uncharacterized protein conserved in archaea. (141 aa)
AGN26010.1COG4050 Uncharacterized protein conserved in archaea. (146 aa)
AGN26011.1Putative methanogenesis marker protein 15; COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain). (410 aa)
AGN26012.1COG4051 Uncharacterized protein conserved in archaea. (184 aa)
AGN26013.1Methanogenesis marker protein 7; COG4052 Uncharacterized protein related to methyl coenzyme M reductase subunit C. (309 aa)
AGN26014.1Iron-sulfur flavoprotein; COG0655 Multimeric flavodoxin WrbA. (166 aa)
AGN26015.1Hypothetical protein. (158 aa)
AGN26087.1Methylcobalamin:coenzyme M methyltransferase; COG0407 Uroporphyrinogen-III decarboxylase. (342 aa)
AGN26195.1Hypothetical protein. (207 aa)
AGN26198.1Hydrogenase isoenzymes formation protein HypD; COG0409 Hydrogenase maturation factor. (357 aa)
hypACOG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression). (124 aa)
AGY50174.1Monomethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (463 aa)
AGN26247.1Monomethylamine methyltransferase corrinoid protein; COG5012 Predicted cobalamin binding protein. (218 aa)
AGN26248.1COG3894 Uncharacterized metal-binding protein. (544 aa)
AGN26249.1COG0334 Glutamate dehydrogenase/leucine dehydrogenase. (279 aa)
AGN26250.13-methylornithine--L-lysine ligase; COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). (390 aa)
AGN26251.1COG0502 Biotin synthase and related enzymes. (360 aa)
AGN26252.1COG0016 Phenylalanyl-tRNA synthetase alpha subunit. (275 aa)
AGN26253.1Monomethylamine methyltransferase corrinoid protein; COG5012 Predicted cobalamin binding protein. (213 aa)
AGY50175.1Monomethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (455 aa)
AGN26255.1Dimethylamine permease; COG0531 Amino acid transporters. (485 aa)
AGY50176.1Hypothetical protein. (49 aa)
AGN26256.1COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. (485 aa)
AGN26257.1Trimethylamine methyltransferase corrinoid protein; COG5012 Predicted cobalamin binding protein. (216 aa)
AGY50177.1COG5598 Trimethylamine:corrinoid methyltransferase; pyrrolysine-containing; Belongs to the trimethylamine methyltransferase family. (496 aa)
AGY50178.1Dimethylamine:corrinoid methyltransferase; pyrrolysine-containing. (469 aa)
AGN26262.1Dimethylamine methyltransferase corrinoid protein; COG5012 Predicted cobalamin binding protein. (214 aa)
AGN26293.1COG0407 Uroporphyrinogen-III decarboxylase. (338 aa)
AGN26402.1uroporphyrinogen-III decarboxylase. (342 aa)
AGN26408.1Hypothetical protein. (105 aa)
AGN26462.1Putative methanogenesis marker protein 2; COG2144 Selenophosphate synthetase-related proteins. (333 aa)
AGN26653.1COG0671 Membrane-associated phospholipid phosphatase. (184 aa)
AGY50193.1Phosphotransacetylase-like protein; COG4002 Predicted phosphotransacetylase. (254 aa)
AGN26655.1COG0720 6-pyruvoyl-tetrahydropterin synthase. (161 aa)
queCpreQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (227 aa)
queERadical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (211 aa)
AGN26679.1Uroporphyrinogen decarboxylase. (344 aa)
AGN26744.1Hypothetical protein. (185 aa)
AGN26870.1COG4014 Uncharacterized protein conserved in archaea. (91 aa)
AGN26871.1Methyl coenzyme M reductase alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (551 aa)
AGN26872.1COG4057 Methyl coenzyme M reductase, gamma subunit. (257 aa)
AGN26873.1COG4055 Methyl coenzyme M reductase, subunit D. (137 aa)
AGN26874.1COG4054 Methyl coenzyme M reductase, beta subunit. (440 aa)
AGN26875.1Hypothetical protein. (209 aa)
AGN26876.1Hypothetical protein. (399 aa)
AGY50213.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (276 aa)
AGN26878.1Hypothetical protein. (203 aa)
AGN26882.1MapA; COG3894 Uncharacterized metal-binding protein. (545 aa)
AGN26883.1Methylcobalamin:coenzyme M methyltransferase; COG0407 Uroporphyrinogen-III decarboxylase. (332 aa)
AGN26884.1COG5012 Predicted cobalamin binding protein. (214 aa)
AGY50225.1Zn-dependent hydrolase (beta-lactamase superfamily) protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I. (253 aa)
AGN27178.1Hypothetical protein. (175 aa)
AGN27180.1COG3894 Uncharacterized metal-binding protein. (577 aa)
AGN27181.1Hypothetical protein; COG0620 Methionine synthase II (cobalamin-independent). (339 aa)
AGN27182.1Carbon monoxide dehydrogenase accessory protein CooC; COG3640 CO dehydrogenase maturation factor. (252 aa)
AGN27184.1COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein). (440 aa)
AGN27185.1COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein). (298 aa)
AGN27186.1Bifunctional acetyl-CoA decarbonylase/synthase complex subunit alpha/beta; COG1152 CO dehydrogenase/acetyl-CoA synthase alpha subunit. (711 aa)
Your Current Organism:
Methanomassiliicoccus intestinalis
NCBI taxonomy Id: 1295009
Other names: C. Methanomassiliicoccus intestinalis Issoire-Mx1, Candidatus Methanomassiliicoccus intestinalis Issoire-Mx1
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