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| | AGN25421.1 | dCMP deaminase; COG2131 Deoxycytidylate deaminase. (151 aa) |
| | fhs | Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. (549 aa) |
| | AGN25461.1 | COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). (518 aa) |
| | AGN25463.1 | Phosphoenolpyruvate carboxylase; COG1892 Uncharacterized protein conserved in archaea. (457 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (310 aa) |
| | AGN25529.1 | COG0560 Phosphoserine phosphatase. (228 aa) |
| | thyX | Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (229 aa) |
| | AGN25563.1 | COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (572 aa) |
| | pdxS | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (298 aa) |
| | AGN25574.1 | COG0436 Aspartate/tyrosine/aromatic aminotransferase. (386 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (176 aa) |
| | gap | COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase. (338 aa) |
| | AGN25629.1 | COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. (279 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (329 aa) |
| | pgk | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (403 aa) |
| | AGN25639.1 | COG0527 Aspartokinases; Belongs to the aspartokinase family. (455 aa) |
| | AGN25653.1 | 4Fe-4S ferredoxin; COG1142 Fe-S-cluster-containing hydrogenase components 2. (144 aa) |
| | AGN25656.1 | COG0547 Anthranilate phosphoribosyltransferase. (367 aa) |
| | AGN25657.1 | Alcohol dehydrogenase, zinc-containing; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. (338 aa) |
| | AGN25658.1 | COG0518 GMP synthase - Glutamine amidotransferase domain. (190 aa) |
| | AGN25659.1 | COG0518 GMP synthase - Glutamine amidotransferase domain. (429 aa) |
| | guaAB | GMP synthase subunit B; Catalyzes the synthesis of GMP from XMP. (315 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (159 aa) |
| | AGN25664.1 | COG0524 Sugar kinases, ribokinase family. (306 aa) |
| | AGN25684.1 | Putative uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase); Catalyzes the reversible phosphorylation of UMP to UDP. (227 aa) |
| | AGN25687.1 | Sortase-related acyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (164 aa) |
| | AGN25688.1 | COG0095 Lipoate-protein ligase A. (162 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (474 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (421 aa) |
| | AGN25753.1 | COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. (247 aa) |
| | AGN25754.1 | 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family protein; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (186 aa) |
| | AGN25755.1 | COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit. (91 aa) |
| | AGN25756.1 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. (388 aa) |
| | AGN25757.1 | COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (313 aa) |
| | AGN25762.1 | COG2252 Permeases. (434 aa) |
| | AGN25848.1 | COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins. (186 aa) |
| | AGN25882.1 | COG0460 Homoserine dehydrogenase. (332 aa) |
| | AGN25883.1 | Alpha-isopropylmalate/homocitrate synthase family transferase; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. (522 aa) |
| | AGN25897.1 | COG0473 Isocitrate/isopropylmalate dehydrogenase. (398 aa) |
| | AGN25918.1 | Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (185 aa) |
| | pyrI | Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (151 aa) |
| | pyrB | COG0540 Aspartate carbamoyltransferase, catalytic chain. (312 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (225 aa) |
| | pdxT | Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (196 aa) |
| | AGN25979.1 | COG1042 Acyl-CoA synthetase (NDP forming). (699 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa) |
| | AGN25987.1 | COG3635 Predicted phosphoglycerate mutase, AP superfamily. (343 aa) |
| | carA | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. (359 aa) |
| | carB | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. (1070 aa) |
| | AGN26021.1 | COG0546 Predicted phosphatases. (220 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (435 aa) |
| | AGN26031.1 | Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; COG0388 Predicted amidohydrolase. (278 aa) |
| | AGN26073.1 | Thymidylate kinase, putative; COG0125 Thymidylate kinase. (194 aa) |
| | AGN26103.1 | COG1048 Aconitase A. (872 aa) |
| | AGN26108.1 | COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (217 aa) |
| | AGN26124.1 | COG0436 Aspartate/tyrosine/aromatic aminotransferase. (372 aa) |
| | argH | COG0165 Argininosuccinate lyase. (482 aa) |
| | argG | COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (429 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (339 aa) |
| | argJ | Glutamate N-acetyltransferase / N- acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (408 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (264 aa) |
| | AGN26133.1 | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (384 aa) |
| | AGN26153.1 | Alanine aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (399 aa) |
| | AGN26159.1 | Bifunctional phosphoglucose/phosphomannose isomerase; COG0166 Glucose-6-phosphate isomerase. (347 aa) |
| | glyA | COG0112 Glycine/serine hydroxymethyltransferase. (425 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa) |
| | AGN26200.1 | COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (543 aa) |
| | AGN26201.1 | Cupin domain/Helix-turn-helix protein; COG1396 Predicted transcriptional regulators. (194 aa) |
| | AGN26202.1 | Hypothetical protein; COG0455 ATPases involved in chromosome partitioning. (217 aa) |
| | AGN26203.1 | 2-oxoglutarate ferredoxin oxidoreductase, delta subunit; COG1146 Ferredoxin. (69 aa) |
| | AGN26204.1 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. (353 aa) |
| | AGN26205.1 | Thiamine pyrophosphate TPP-binding domain-containing protein; COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (251 aa) |
| | AGN26206.1 | COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (178 aa) |
| | pyrD | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. (302 aa) |
| | AGN26219.1 | Dihydroorotate dehydrogenase electron transfer subunit; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. (255 aa) |
| | AGN26435.1 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (453 aa) |
| | AGN26442.1 | COG0385 Predicted Na+-dependent transporter. (312 aa) |
| | hisD | Bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (416 aa) |
| | AGN26459.1 | Hypothetical protein; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (197 aa) |
| | AGN26469.1 | COG2873 O-acetylhomoserine sulfhydrylase. (427 aa) |
| | metAA | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (305 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (225 aa) |
| | fbp | Fructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (380 aa) |
| | AGN26538.1 | Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. (575 aa) |
| | AGN26539.1 | Hypothetical protein; COG0440 Acetolactate synthase, small (regulatory) subunit. (168 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (433 aa) |
| | AGN26574.1 | 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family protein; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (186 aa) |
| | vorD | COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit. (89 aa) |
| | AGN26576.1 | COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. (385 aa) |
| | AGN26577.1 | COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (292 aa) |
| | AGN26578.1 | Indolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (604 aa) |
| | AGN26579.1 | Indolepyruvate oxidoreductase subunit beta; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (202 aa) |
| | apgM | Cofactor-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (410 aa) |
| | AGN26637.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (769 aa) |
| | AGN26659.1 | 2-isopropylmalate synthase; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. (529 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (413 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (160 aa) |
| | AGN26662.1 | COG0473 Isocitrate/isopropylmalate dehydrogenase. (370 aa) |
| | dcd | COG0717 Deoxycytidine deaminase. (164 aa) |
| | AGY50203.1 | Aminotransferase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (354 aa) |
| | AGN26757.1 | Hypothetical protein; COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase. (264 aa) |
| | aroA | Fructose-bisphosphate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (263 aa) |
| | aroB | 3-dehydroquinate synthase II; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (342 aa) |
| | aroE | Hypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (473 aa) |
| | aroK | COG1685 Archaeal shikimate kinase. (284 aa) |
| | aroA-2 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (418 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (359 aa) |
| | AGN26764.1 | Hypothetical protein; COG1605 Chorismate mutase. (355 aa) |
| | AGN26765.1 | COG0136 Aspartate-semialdehyde dehydrogenase. (353 aa) |
| | AGN26766.1 | Hypothetical protein. (389 aa) |
| | AGN26767.1 | Ferridoxin; COG1145 Ferredoxin. (134 aa) |
| | AGN26768.1 | Hypothetical protein. (237 aa) |
| | AGN26769.1 | Beta-lactamase; COG2333 Predicted hydrolase (metallo-beta-lactamase superfamily). (496 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (287 aa) |
| | hisC | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (347 aa) |
| | AGY50204.1 | Imidazole glycerol phosphate synthase amidotransferase subunit; COG0118 Glutamine amidotransferase. (185 aa) |
| | hisA | COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. (235 aa) |
| | hisB | COG0131 Imidazoleglycerol-phosphate dehydratase. (187 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (250 aa) |
| | hisI | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; COG0139 Phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family. (203 aa) |
| | AGN26777.1 | Hypothetical protein; COG1387 Histidinol phosphatase and related hydrolases of the PHP family. (217 aa) |
| | AGN26778.1 | COG0077 Prephenate dehydratase. (270 aa) |
| | AGN26779.1 | Hypothetical protein. (182 aa) |
| | ilvD | COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (548 aa) |
| | AGN26797.1 | COG0621 2-methylthioadenine synthetase. (410 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) |
| | purC | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. (301 aa) |
| | AGN26842.1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (400 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (310 aa) |
| | AGN26888.1 | COG0078 Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (303 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (296 aa) |
| | AGN26955.1 | 3-hexulose-6-phosphate isomerase (6- phospho-3-hexuloisomerase) (PHI); COG0794 Predicted sugar phosphate isomerase involved in capsule formation. (179 aa) |
| | tal | Translaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (229 aa) |
| | AGN27066.1 | COG3958 Transketolase, C-terminal subunit. (315 aa) |
| | AGY50221.1 | COG3959 Transketolase, N-terminal subunit. (278 aa) |
| | AGN27076.1 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (371 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (278 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (774 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (86 aa) |
| | tmk | COG0125 Thymidylate kinase. (202 aa) |
| | AGN27141.1 | 2-methylcitrate synthase/citrate synthase II; COG0372 Citrate synthase. (385 aa) |
| | AGN27187.1 | COG2844 UTP:GlnB (protein PII) uridylyltransferase. (308 aa) |
| | purM | COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. (342 aa) |
| | AGN27198.1 | Tartrate/fumarate subfamily Fe-S type hydro-lyase subunit beta; COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain. (193 aa) |
| | AGY50233.1 | COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain. (277 aa) |
| | AGN27205.1 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (410 aa) |
| | AGN27209.1 | Radical SAM domain protein; COG1856 Uncharacterized homolog of biotin synthetase. (266 aa) |
| | AGN27213.1 | Bifunctional hexulose-6-phosphate synthase/ribonuclease regulator; COG0269 3-hexulose-6-phosphate synthase and related proteins. (431 aa) |
| | AGN27215.1 | COG0183 Acetyl-CoA acetyltransferase. (392 aa) |
| | purD | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. (440 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (215 aa) |
| | AGN27237.1 | COG0281 Malic enzyme. (447 aa) |
