STRINGSTRING
AGN25463.1 AGN25463.1 AGN25563.1 AGN25563.1 pdxS pdxS AGN25574.1 AGN25574.1 gap gap pgk pgk AGN25653.1 AGN25653.1 AGN25754.1 AGN25754.1 AGN25755.1 AGN25755.1 AGN25756.1 AGN25756.1 AGN25757.1 AGN25757.1 AGN25897.1 AGN25897.1 rpiA rpiA pdxT pdxT AGN25979.1 AGN25979.1 AGN25987.1 AGN25987.1 AGN26031.1 AGN26031.1 AGN26103.1 AGN26103.1 AGN26108.1 AGN26108.1 AGN26124.1 AGN26124.1 AGN26159.1 AGN26159.1 eno eno AGN26200.1 AGN26200.1 AGN26201.1 AGN26201.1 AGN26202.1 AGN26202.1 AGN26203.1 AGN26203.1 AGN26204.1 AGN26204.1 AGN26205.1 AGN26205.1 AGN26206.1 AGN26206.1 tpiA tpiA fbp fbp AGN26574.1 AGN26574.1 vorD vorD AGN26576.1 AGN26576.1 AGN26577.1 AGN26577.1 AGN26578.1 AGN26578.1 AGN26579.1 AGN26579.1 apgM apgM AGN26637.1 AGN26637.1 AGN26955.1 AGN26955.1 tal tal AGN27066.1 AGN27066.1 AGY50221.1 AGY50221.1 AGN27141.1 AGN27141.1 AGN27198.1 AGN27198.1 AGY50233.1 AGY50233.1 AGN27213.1 AGN27213.1 AGN27215.1 AGN27215.1 AGN27237.1 AGN27237.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGN25463.1Phosphoenolpyruvate carboxylase; COG1892 Uncharacterized protein conserved in archaea. (457 aa)
AGN25563.1COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (572 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (298 aa)
AGN25574.1COG0436 Aspartate/tyrosine/aromatic aminotransferase. (386 aa)
gapCOG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase. (338 aa)
pgkCOG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (403 aa)
AGN25653.14Fe-4S ferredoxin; COG1142 Fe-S-cluster-containing hydrogenase components 2. (144 aa)
AGN25754.12-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family protein; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (186 aa)
AGN25755.1COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit. (91 aa)
AGN25756.1Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. (388 aa)
AGN25757.1COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (313 aa)
AGN25897.1COG0473 Isocitrate/isopropylmalate dehydrogenase. (398 aa)
rpiARibose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (225 aa)
pdxTGlutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (196 aa)
AGN25979.1COG1042 Acyl-CoA synthetase (NDP forming). (699 aa)
AGN25987.1COG3635 Predicted phosphoglycerate mutase, AP superfamily. (343 aa)
AGN26031.1Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; COG0388 Predicted amidohydrolase. (278 aa)
AGN26103.1COG1048 Aconitase A. (872 aa)
AGN26108.1COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (217 aa)
AGN26124.1COG0436 Aspartate/tyrosine/aromatic aminotransferase. (372 aa)
AGN26159.1Bifunctional phosphoglucose/phosphomannose isomerase; COG0166 Glucose-6-phosphate isomerase. (347 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
AGN26200.1COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (543 aa)
AGN26201.1Cupin domain/Helix-turn-helix protein; COG1396 Predicted transcriptional regulators. (194 aa)
AGN26202.1Hypothetical protein; COG0455 ATPases involved in chromosome partitioning. (217 aa)
AGN26203.12-oxoglutarate ferredoxin oxidoreductase, delta subunit; COG1146 Ferredoxin. (69 aa)
AGN26204.1Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. (353 aa)
AGN26205.1Thiamine pyrophosphate TPP-binding domain-containing protein; COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (251 aa)
AGN26206.1COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (178 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (225 aa)
fbpFructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (380 aa)
AGN26574.12-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family protein; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (186 aa)
vorDCOG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit. (89 aa)
AGN26576.1COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. (385 aa)
AGN26577.1COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (292 aa)
AGN26578.1Indolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (604 aa)
AGN26579.1Indolepyruvate oxidoreductase subunit beta; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (202 aa)
apgMCofactor-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (410 aa)
AGN26637.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (769 aa)
AGN26955.13-hexulose-6-phosphate isomerase (6- phospho-3-hexuloisomerase) (PHI); COG0794 Predicted sugar phosphate isomerase involved in capsule formation. (179 aa)
talTranslaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (229 aa)
AGN27066.1COG3958 Transketolase, C-terminal subunit. (315 aa)
AGY50221.1COG3959 Transketolase, N-terminal subunit. (278 aa)
AGN27141.12-methylcitrate synthase/citrate synthase II; COG0372 Citrate synthase. (385 aa)
AGN27198.1Tartrate/fumarate subfamily Fe-S type hydro-lyase subunit beta; COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain. (193 aa)
AGY50233.1COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain. (277 aa)
AGN27213.1Bifunctional hexulose-6-phosphate synthase/ribonuclease regulator; COG0269 3-hexulose-6-phosphate synthase and related proteins. (431 aa)
AGN27215.1COG0183 Acetyl-CoA acetyltransferase. (392 aa)
AGN27237.1COG0281 Malic enzyme. (447 aa)
Your Current Organism:
Methanomassiliicoccus intestinalis
NCBI taxonomy Id: 1295009
Other names: C. Methanomassiliicoccus intestinalis Issoire-Mx1, Candidatus Methanomassiliicoccus intestinalis Issoire-Mx1
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