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| | cdc6 | Cell division control protein 6 Cdc6/Orc1; Involved in regulation of DNA replication. (413 aa) |
| | AGN25422.1 | H(+)-transporting ATP synthase, subunit H. (114 aa) |
| | rpl1P | 50S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa) |
| | rplP0 | Acidic ribosomal protein P0; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (332 aa) |
| | rpl12p | 50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (102 aa) |
| | rrmJ | 23S rRNA methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (210 aa) |
| | AGN25442.1 | Putative ATP-dependent helicase; COG1201 Lhr-like helicases. (910 aa) |
| | xerA | Tyrosine recombinase Xer; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. XerA subfamily. (319 aa) |
| | AGN25502.1 | COG1201 Lhr-like helicases. (646 aa) |
| | AGN25517.1 | COG0863 DNA modification methylase. (305 aa) |
| | AGN25527.1 | Putative AAA-ATPase. (480 aa) |
| | AGN25528.1 | Hypothetical protein; COG1326 Uncharacterized archaeal Zn-finger protein. (173 aa) |
| | rps17E | COG1383 Ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (63 aa) |
| | AGN25534.1 | COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP. (640 aa) |
| | AGN25550.1 | Ig domain-containing protein group 2 domain-containing protein. (1097 aa) |
| | rps2P | COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (203 aa) |
| | AGN25568.1 | COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins. (447 aa) |
| | AGN25571.1 | Ribosome biogenesis protein. (187 aa) |
| | AGN25584.1 | COG2073 Cobalamin biosynthesis protein CbiG. (347 aa) |
| | AGN25585.1 | COG2099 Precorrin-6x reductase. (668 aa) |
| | AGN25596.1 | Uracil-DNA glycosylase, family 4; COG1573 Uracil-DNA glycosylase. (175 aa) |
| | csl4 | RNA-binding protein, containing S1 domain; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (184 aa) |
| | AGN25634.1 | Radical SAM protein; COG1533 DNA repair photolyase. (302 aa) |
| | AGN25635.1 | COG0266 Formamidopyrimidine-DNA glycosylase. (274 aa) |
| | AGN25644.1 | COG0350 Methylated DNA-protein cysteine methyltransferase. (323 aa) |
| | AGN25675.1 | Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (115 aa) |
| | rps15p | COG0184 Ribosomal protein S15P/S13E. (151 aa) |
| | prf1 | Peptide chain release factor 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (417 aa) |
| | argS | COG0018 Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (570 aa) |
| | AGN25702.1 | COG2035 Predicted membrane protein. (295 aa) |
| | rps3ae | COG1890 Ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (261 aa) |
| | AGN25725.1 | Hypothetical protein. (146 aa) |
| | rpl37e | 50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (55 aa) |
| | AGN25747.1 | COG2016 Predicted RNA-binding protein (contains PUA domain). (165 aa) |
| | AGN25772.1 | Alanyl-tRNA synthetase; COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain. (393 aa) |
| | aspS | aspartyl-tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (609 aa) |
| | gatB | aspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (448 aa) |
| | gatA | COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases. (436 aa) |
| | AGN25780.1 | glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit; COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit. (92 aa) |
| | rnhB | Ribonuclease RNAseHII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (215 aa) |
| | tyrS | tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (349 aa) |
| | AGN25807.1 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (748 aa) |
| | rpl3p | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (332 aa) |
| | rpl4lp | 50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (254 aa) |
| | rpl23 | 50S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (93 aa) |
| | rpl2p | COG0090 Ribosomal protein L2. (200 aa) |
| | rps19p | 30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (154 aa) |
| | rpl22 | Ribosomal protein L22(archaeal)/L17(eukaryotic/archaeal); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (148 aa) |
| | rps3p | 30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (263 aa) |
| | rpl29 | COG0255 Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (67 aa) |
| | AGN25821.1 | COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related proteins; Belongs to the SUI1 family. (99 aa) |
| | rps17 | Archaeal ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (109 aa) |
| | rpl14p | 50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (134 aa) |
| | rpl24p | 50S ribosomal protein L24P; Located at the polypeptide exit tunnel on the outside of the subunit. (124 aa) |
| | rps4e | COG1471 Ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (236 aa) |
| | rpl5p | 50S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (171 aa) |
| | rps14P | 30S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (48 aa) |
| | rps8p | 30S ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (129 aa) |
| | rpl6p | 50S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (184 aa) |
| | rpl32e | COG1717 Ribosomal protein L32E; Belongs to the eukaryotic ribosomal protein eL32 family. (160 aa) |
| | rpl19e | 50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (152 aa) |
| | rpl18p | 50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (166 aa) |
| | rps5p | 30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (229 aa) |
| | rpl30p | COG1841 Ribosomal protein L30/L7E. (154 aa) |
| | rpl15p | 50S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (142 aa) |
| | rpl37ae | 50S ribosomal protein L37Ae; Binds to the 23S rRNA. (96 aa) |
| | rrp42 | Exosome complex RNA-binding protein Rrp42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (256 aa) |
| | rrp41 | Exosome complex exonuclease Rrp41; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (262 aa) |
| | rrp4 | Exosome complex RNA-binding protein Rrp4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (232 aa) |
| | psmA | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (240 aa) |
| | rps8e | COG2007 Ribosomal protein S8E. (127 aa) |
| | eif2b | Translation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (248 aa) |
| | AGN25903.1 | COG1091 dTDP-4-dehydrorhamnose reductase. (316 aa) |
| | AGN25908.1 | Hef nuclease; COG1111 ERCC4-like helicases. (524 aa) |
| | lig | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (585 aa) |
| | radB | DNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. (221 aa) |
| | rpl44e | 50S ribosomal protein L44e; Binds to the 23S rRNA. (92 aa) |
| | rps27e | COG2051 Ribosomal protein S27E. (59 aa) |
| | AGN25937.1 | COG1093 Translation initiation factor 2, alpha subunit (eIF-2alpha). (261 aa) |
| | AGN25945.1 | PHP C-terminal domain protein; COG0613 Predicted metal-dependent phosphoesterases (PHP family). (291 aa) |
| | AGN25964.1 | Cell wall/surface repeat-containing protein. (1058 aa) |
| | radA | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (313 aa) |
| | AGN25969.1 | tRNA-(G10-N2) methyltransferase; COG1041 Predicted DNA modification methylase. (338 aa) |
| | AGN25998.1 | S-layer protein. (1312 aa) |
| | AGN26000.1 | SMC domain-containing protein; COG0419 ATPase involved in DNA repair. (794 aa) |
| | AGN26001.1 | DNA double-strand break repair protein; COG0420 DNA repair exonuclease. (375 aa) |
| | AGN26018.1 | Mrr restriction system protein; COG1715 Restriction endonuclease. (299 aa) |
| | AGN26023.1 | COG1184 Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family; Belongs to the eIF-2B alpha/beta/delta subunits family. (280 aa) |
| | AGN26063.1 | Hypothetical protein; COG3357 Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon. (239 aa) |
| | AGN26064.1 | Hypothetical protein; COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain. (196 aa) |
| | rps24e | COG2004 Ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (105 aa) |
| | rps27ae | COG1998 Ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. (65 aa) |
| | AGN26112.1 | Hypothetical protein; COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain. (194 aa) |
| | AGN26116.1 | COG0013 Alanyl-tRNA synthetase. (593 aa) |
| | rps13p | 30S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (173 aa) |
| | rps4p | 30S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (214 aa) |
| | rps11p | 30S ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (127 aa) |
| | ogt | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (180 aa) |
| | AGY50169.1 | PHP domain protein; COG0613 Predicted metal-dependent phosphoesterases (PHP family). (308 aa) |
| | AGN26146.1 | ATPase RIL; COG1245 Predicted ATPase, RNase L inhibitor (RLI) homolog. (560 aa) |
| | AGN26147.1 | Hypothetical protein; COG0613 Predicted metal-dependent phosphoesterases (PHP family). (218 aa) |
| | metG | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (736 aa) |
| | rfc | Replication factor C small subunit; COG0470 ATPase involved in DNA replication. (284 aa) |
| | rpl40e | COG1552 Ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (49 aa) |
| | nth | HhH-GPD family protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (218 aa) |
| | nfo | Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (277 aa) |
| | cysS | COG0215 Cysteinyl-tRNA synthetase. (464 aa) |
| | AGN26252.1 | COG0016 Phenylalanyl-tRNA synthetase alpha subunit. (275 aa) |
| | AGN26264.1 | Ribonucleoside-triphosphate reductase class III catalytic subunit; COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase. (698 aa) |
| | AGN26274.1 | Hypothetical protein. (901 aa) |
| | cas1 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (330 aa) |
| | cas2 | CRISPR protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (98 aa) |
| | AGY50181.1 | peptidyl-tRNA hydrolase. (144 aa) |
| | AGN26300.1 | Radical SAM-superfamily protein; COG1533 DNA repair photolyase. (292 aa) |
| | AGN26307.1 | DNA methylase N-4/N-6 domain-containing protein; COG0863 DNA modification methylase. (301 aa) |
| | AGN26355.1 | Hypothetical protein. (321 aa) |
| | AGN26370.1 | D12 class N6 adenine-specific DNA methyltransferase; COG0338 Site-specific DNA methylase. (287 aa) |
| | AGN26381.1 | Site-specific recombinase XerD; COG0582 Integrase. (370 aa) |
| | valS | valyl-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (870 aa) |
| | AGN26391.1 | COG0423 Glycyl-tRNA synthetase (class II). (569 aa) |
| | AGN26423.1 | Site-specific recombinase for integration and excision; COG1961 Site-specific recombinases, DNA invertase Pin homologs. (275 aa) |
| | AGN26424.1 | Site-specific recombinase for integration and excision; COG1961 Site-specific recombinases, DNA invertase Pin homologs. (271 aa) |
| | AGY50184.1 | COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins. (137 aa) |
| | AGN26427.1 | COG1533 DNA repair photolyase. (259 aa) |
| | AGN26428.1 | Hypothetical protein; Involved in DNA damage repair. (427 aa) |
| | AGN26430.1 | PHP domain-containing protein; COG1796 DNA polymerase IV (family X). (542 aa) |
| | trmY | Hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (196 aa) |
| | pheT | COG0072 Phenylalanyl-tRNA synthetase beta subunit. (551 aa) |
| | AGN26450.1 | Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism. (134 aa) |
| | eif6 | Translation initiation factor IF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (218 aa) |
| | rpl31e | COG2097 Ribosomal protein L31E; Belongs to the ribosomal protein L31e family. (90 aa) |
| | rpl39e | COG2167 Ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | rps19e | 30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (142 aa) |
| | leuS | COG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1015 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (469 aa) |
| | AGN26512.1 | Transposase, IS4 family protein; COG5421 Transposase. (321 aa) |
| | AGY50190.1 | COG0338 Site-specific DNA methylase. (242 aa) |
| | AGN26516.1 | Hypothetical protein; COG4172 ABC-type uncharacterized transport system, duplicated ATPase component. (747 aa) |
| | AGN26517.1 | COG0464 ATPases of the AAA+ class. (384 aa) |
| | AGN26519.1 | Hypothetical protein. (211 aa) |
| | aspC | aspartyl-tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (439 aa) |
| | AGN26556.1 | COG1867 N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (365 aa) |
| | gltX | glutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (559 aa) |
| | rfcL | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (463 aa) |
| | AGN26601.1 | Hypothetical protein; COG1533 DNA repair photolyase. (290 aa) |
| | ileS | isoleucyl-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1047 aa) |
| | fen | Flap structure-specific endonuclease FEN-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision [...] (350 aa) |
| | lysK | COG1384 Lysyl-tRNA synthetase (class I); Belongs to the class-I aminoacyl-tRNA synthetase family. (514 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa) |
| | rpl10e | COG0197 Ribosomal protein L16/L10E; Belongs to the universal ribosomal protein uL16 family. (172 aa) |
| | AGN26685.1 | COG0441 Threonyl-tRNA synthetase. (612 aa) |
| | AGN26688.1 | COG0438 Glycosyltransferase. (358 aa) |
| | eif1a | Translation initiation factor IF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (108 aa) |
| | rpl21e | COG2139 Ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa) |
| | ksgA | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (263 aa) |
| | AGN26701.1 | COG0417 DNA polymerase elongation subunit (family B). (802 aa) |
| | polC | DNA polymerase D large subunit (DPL); Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1116 aa) |
| | AGN26722.1 | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase. (190 aa) |
| | AGN26724.1 | Elongation factor Tu domain-containing protein; COG3276 Selenocysteine-specific translation elongation factor. (313 aa) |
| | hisS | COG0124 Histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (413 aa) |
| | AGN26740.1 | Small GTP-binding protein domain protein; COG1163 Predicted GTPase. (371 aa) |
| | top6B | DNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (666 aa) |
| | top6A | DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (366 aa) |
| | pelA | Putative cell division protein; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (349 aa) |
| | AGN26777.1 | Hypothetical protein; COG1387 Histidinol phosphatase and related hydrolases of the PHP family. (217 aa) |
| | rps10p | 30S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa) |
| | tuf | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (421 aa) |
| | fusA | Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (732 aa) |
| | rps7 | 30S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (195 aa) |
| | rps12P | 30S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa) |
| | AGN26790.1 | peptidyl-tRNA hydrolase. (117 aa) |
| | AGN26823.1 | Hypothetical protein. (347 aa) |
| | AGN26837.1 | Hypothetical protein. (369 aa) |
| | hel308 | Ski2-like helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (731 aa) |
| | AGN26885.1 | Putative phosphoesterase, SbcD/Mre11-related protein; COG1407 Predicted ICC-like phosphoesterases. (241 aa) |
| | AGN26890.1 | SMC domain-containing protein; COG1196 Chromosome segregation ATPases. (427 aa) |
| | rpl15e | COG1632 Ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. (192 aa) |
| | smc | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1201 aa) |
| | eif5a | Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (126 aa) |
| | AGN26950.1 | Translation initiation factor IF-2B subunit alpha; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (335 aa) |
| | pheS | COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (501 aa) |
| | trpS | Tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (372 aa) |
| | AGN26956.1 | Xylose isomerase domain protein TIM barrel; COG0648 Endonuclease IV. (396 aa) |
| | rpl18e | COG1727 Ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. (120 aa) |
| | rpl13 | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (139 aa) |
| | rps9p | COG0103 Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (133 aa) |
| | AGN26961.1 | D12 class N6 adenine-specific DNA methyltransferase; COG0338 Site-specific DNA methylase. (287 aa) |
| | AGN26967.1 | Resolvase domain protein; COG1961 Site-specific recombinases, DNA invertase Pin homologs. (211 aa) |
| | AGN26991.1 | Hypothetical protein; COG4974 Site-specific recombinase XerD. (313 aa) |
| | rpl11p | 50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (165 aa) |
| | spt5 | Putative transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (291 aa) |
| | AGN27039.1 | tRNA cytosine methylase Pos56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (175 aa) |
| | AGY50219.1 | tRNA 2'-O-methylase; COG1418 Predicted HD superfamily hydrolase. (144 aa) |
| | pcn | Proliferating Cell Nuclear Antigen PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. (245 aa) |
| | AGN27080.1 | Hypothetical protein; COG1082 Sugar phosphate isomerases/epimerases. (250 aa) |
| | polB | DNA polymerase D small subunit (DPS); Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (484 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (383 aa) |
| | eif2g | Translation initiation factor IF-2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (408 aa) |
| | rps6e | COG2125 Ribosomal protein S6E (S10); Belongs to the eukaryotic ribosomal protein eS6 family. (131 aa) |
| | AGY50225.1 | Zn-dependent hydrolase (beta-lactamase superfamily) protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I. (253 aa) |
| | AGN27113.1 | Hypothetical protein; COG4974 Site-specific recombinase XerD. (331 aa) |
| | AGY50226.1 | COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferases. (254 aa) |
| | proS | prolyl-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (468 aa) |
| | infB | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (583 aa) |
| | AGN27157.1 | COG0178 Excinuclease ATPase subunit. (850 aa) |
| | AGN27158.1 | Origin of replication recognition protein / Cell division control protein 6 Cdc6/Orc1; Involved in regulation of DNA replication. (393 aa) |
| | gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (842 aa) |
| | gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (633 aa) |
| | AGN27166.1 | DNA-(apurinic or apyrimidinic site) lyase; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. (263 aa) |
| | AGN27169.1 | Hypothetical protein; COG0582 Integrase. (279 aa) |
| | AGN27173.1 | RNA methyltransferase, TrmH family, group 1; COG0565 rRNA methylase. (238 aa) |
| | priL | Primase large subunit (PriL); Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (352 aa) |
| | rpl24e | 50S ribosomal protein L24e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL24 family. (138 aa) |
| | rps28e | COG2053 Ribosomal protein S28E/S33; Belongs to the eukaryotic ribosomal protein eS28 family. (69 aa) |
| | rpl7ae | 50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (123 aa) |
| | rpl18a | COG2157 Ribosomal protein L20A (L18A). (77 aa) |
| | priS | Primase small subunit (PriS); Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesi [...] (406 aa) |
| | gatE | glutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (619 aa) |
| | gatD | glutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (431 aa) |
| | AGN27225.1 | Oligosaccharyl transferase STT3 subunit; COG1287 Uncharacterized membrane protein, required for N-linked glycosylation. (2117 aa) |
| | AGN27229.1 | COG1911 Ribosomal protein L30E. (92 aa) |
| | ef1B | Elongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (88 aa) |
