STRINGSTRING
AGN25618.1 AGN25618.1 AGN25659.1 AGN25659.1 guaAB guaAB argS argS AGN25706.1 AGN25706.1 tyrS tyrS AGN25931.1 AGN25931.1 AGN26094.1 AGN26094.1 argG argG AGN26138.1 AGN26138.1 metG metG AGN26152.1 AGN26152.1 ribL ribL AGN26161.1 AGN26161.1 AGY50171.1 AGY50171.1 cysS cysS valS valS AGN26393.1 AGN26393.1 AGN26432.1 AGN26432.1 AGN26441.1 AGN26441.1 leuS leuS gltX gltX ileS ileS lysK lysK queC queC nadE nadE AGN26839.1 AGN26839.1 AGN26905.1 AGN26905.1 trpS trpS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGN25618.1Hypothetical protein; COG0301 Thiamine biosynthesis ATP pyrophosphatase. (208 aa)
AGN25659.1COG0518 GMP synthase - Glutamine amidotransferase domain. (429 aa)
guaABGMP synthase subunit B; Catalyzes the synthesis of GMP from XMP. (315 aa)
argSCOG0018 Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (570 aa)
AGN25706.1Hypothetical protein; COG5270 PUA domain (predicted RNA-binding domain). (627 aa)
tyrStyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (349 aa)
AGN25931.1Hypothetical protein; COG2102 Predicted ATPases of PP-loop superfamily. (225 aa)
AGN26094.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (148 aa)
argGCOG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (429 aa)
AGN26138.1COG0367 Asparagine synthase (glutamine-hydrolyzing). (321 aa)
metGMethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (736 aa)
AGN26152.1Hypothetical protein; COG5270 PUA domain (predicted RNA-binding domain). (600 aa)
ribLCytidyltransferase-related enzyme; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (154 aa)
AGN26161.1N-type ATP pyrophosphatase superfamily / TilS and TtcA-like protein; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control. (304 aa)
AGY50171.1COG0367 Asparagine synthase (glutamine-hydrolyzing). (254 aa)
cysSCOG0215 Cysteinyl-tRNA synthetase. (464 aa)
valSvalyl-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (870 aa)
AGN26393.1COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (153 aa)
AGN26432.1Hypothetical protein; COG1606 ATP-utilizing enzymes of the PP-loop superfamily. (261 aa)
AGN26441.1Phosphopantetheine adenylyltransferase/unknown domain fusion protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. (321 aa)
leuSCOG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1015 aa)
gltXglutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (559 aa)
ileSisoleucyl-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1047 aa)
lysKCOG1384 Lysyl-tRNA synthetase (class I); Belongs to the class-I aminoacyl-tRNA synthetase family. (514 aa)
queCpreQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (227 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (263 aa)
AGN26839.1COG1056 Nicotinamide mononucleotide adenylyltransferase. (169 aa)
AGN26905.1tRNA S(4)U 4-thiouridine synthase (former ThiI); COG0301 Thiamine biosynthesis ATP pyrophosphatase. (285 aa)
trpSTryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (372 aa)
Your Current Organism:
Methanomassiliicoccus intestinalis
NCBI taxonomy Id: 1295009
Other names: C. Methanomassiliicoccus intestinalis Issoire-Mx1, Candidatus Methanomassiliicoccus intestinalis Issoire-Mx1
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