(20 nodes) Cul4-RING E3 ubiquitin ligase complex, and COP9 signalosome network (Cryptococcus amylolentus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	L202_07296	Uncharacterized protein. (444 aa)
	L202_07261	WD_REPEATS_REGION domain-containing protein. (686 aa)
	L202_06968	Uncharacterized protein. (361 aa)
	L202_06876	CPSF_A domain-containing protein. (1279 aa)
	L202_07055	MPN domain-containing protein. (367 aa)
	L202_06814	PCI domain-containing protein. (482 aa)
	L202_06648	WD_REPEATS_REGION domain-containing protein. (648 aa)
	L202_06053	TIP120 domain-containing protein. (1264 aa)
	L202_04582	PCI domain-containing protein. (457 aa)
	L202_04600	CULLIN_2 domain-containing protein; Belongs to the cullin family. (841 aa)
	L202_04580	CULLIN_2 domain-containing protein; Belongs to the cullin family. (841 aa)
	L202_03944	PCI domain-containing protein. (540 aa)
	L202_03445	COP9 signalosome complex subunit 5. (366 aa)
	L202_02857	Uncharacterized protein. (560 aa)
	L202_01876	Uncharacterized protein. (789 aa)
	L202_01971	PCI domain-containing protein. (297 aa)
	L202_01918	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (592 aa)
	L202_02440	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (111 aa)
	L202_01333	RING-box protein 1A. (105 aa)
	L202_01402	WD_REPEATS_REGION domain-containing protein. (628 aa)

Your Current Organism:

Cryptococcus amylolentus

NCBI taxonomy Id: 1295533
Other names: C. amylolentus CBS 6039, Cryptococcus amylolentus CBS 6039, Cryptococcus amylolentus CBS6039

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L202_01333	L202_01402	A0A1E3I3A3	A0A1E3I3Y9	RING-box protein 1A.	WD_REPEATS_REGION domain-containing protein.	0.721
L202_01333	L202_01876	A0A1E3I3A3	A0A1E3HYV6	RING-box protein 1A.	Uncharacterized protein.	0.699
L202_01333	L202_01918	A0A1E3I3A3	A0A1E3I0H2	RING-box protein 1A.	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	0.911
L202_01333	L202_01971	A0A1E3I3A3	A0A1E3HYX2	RING-box protein 1A.	PCI domain-containing protein.	0.875
L202_01333	L202_02440	A0A1E3I3A3	A0A1E3I0L3	RING-box protein 1A.	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.998
L202_01333	L202_02857	A0A1E3I3A3	A0A1E3HWH6	RING-box protein 1A.	Uncharacterized protein.	0.929
L202_01333	L202_03445	A0A1E3I3A3	A0A1E3HVA6	RING-box protein 1A.	COP9 signalosome complex subunit 5.	0.956
L202_01333	L202_03944	A0A1E3I3A3	A0A1E3HPL6	RING-box protein 1A.	PCI domain-containing protein.	0.959
L202_01333	L202_04580	A0A1E3I3A3	A0A1E3HNW1	RING-box protein 1A.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.944
L202_01333	L202_04582	A0A1E3I3A3	A0A1E3HM33	RING-box protein 1A.	PCI domain-containing protein.	0.975
L202_01333	L202_04600	A0A1E3I3A3	A0A1E3HM58	RING-box protein 1A.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.944
L202_01333	L202_06053	A0A1E3I3A3	A0A1E3HKZ8	RING-box protein 1A.	TIP120 domain-containing protein.	0.978
L202_01333	L202_06648	A0A1E3I3A3	A0A1E3HGQ0	RING-box protein 1A.	WD_REPEATS_REGION domain-containing protein.	0.991
L202_01333	L202_06814	A0A1E3I3A3	A0A1E3HG70	RING-box protein 1A.	PCI domain-containing protein.	0.965
L202_01333	L202_06876	A0A1E3I3A3	A0A1E3HEC2	RING-box protein 1A.	CPSF_A domain-containing protein.	0.998
L202_01333	L202_06968	A0A1E3I3A3	A0A1E3HE71	RING-box protein 1A.	Uncharacterized protein.	0.612
L202_01333	L202_07055	A0A1E3I3A3	A0A1E3HEF5	RING-box protein 1A.	MPN domain-containing protein.	0.929
L202_01333	L202_07261	A0A1E3I3A3	A0A1E3HE55	RING-box protein 1A.	WD_REPEATS_REGION domain-containing protein.	0.721
L202_01333	L202_07296	A0A1E3I3A3	A0A1E3HBQ5	RING-box protein 1A.	Uncharacterized protein.	0.673
L202_01402	L202_01333	A0A1E3I3Y9	A0A1E3I3A3	WD_REPEATS_REGION domain-containing protein.	RING-box protein 1A.	0.721