(32 nodes) Ubiquitin-dependent ERAD pathway network (Cryptococcus amylolentus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	L202_03407	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (268 aa)
	L202_02751	U-box domain-containing protein. (1160 aa)
	L202_02670	J domain-containing protein. (362 aa)
	L202_03199	UAS domain-containing protein. (539 aa)
	L202_02402	TPR_REGION domain-containing protein. (358 aa)
	L202_01101	UV excision repair protein Rad23. (377 aa)
	L202_01156	Uncharacterized protein. (876 aa)
	L202_01802	N-acetyltransferase domain-containing protein. (264 aa)
	L202_00176	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family. (223 aa)
	L202_00491	Nuclear protein localization protein 4. (681 aa)
	L202_00901	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (407 aa)
	L202_07527	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (235 aa)
	L202_07447	Chaperone DnaK; Belongs to the heat shock protein 70 family. (674 aa)
	L202_08384	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (877 aa)
	L202_03314	Uncharacterized protein. (487 aa)
	L202_04451	UBX domain-containing protein. (295 aa)
	L202_04325	UBIQUITIN_CONJUGAT_2 domain-containing protein. (311 aa)
	L202_04265	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (175 aa)
	L202_04062	Uncharacterized protein. (287 aa)
	L202_04053	Uncharacterized protein. (782 aa)
	L202_05306	bVLRF1 domain-containing protein. (693 aa)
	L202_05563	RING-type domain-containing protein. (750 aa)
	L202_05484	UBIQUITIN_CONJUGAT_2 domain-containing protein. (251 aa)
	L202_05784	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (790 aa)
	L202_06625	Uncharacterized protein. (370 aa)
	L202_07452	OTU domain-containing protein. (326 aa)
	L202_07117	J domain-containing protein. (441 aa)
	L202_07083	RING-CH-type domain-containing protein. (1500 aa)
	L202_06836	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (601 aa)
	L202_03409	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (810 aa)
	L202_03499	PRKCSH domain-containing protein. (521 aa)
	L202_03525	HECT domain-containing protein. (1053 aa)

Your Current Organism:

Cryptococcus amylolentus

NCBI taxonomy Id: 1295533
Other names: C. amylolentus CBS 6039, Cryptococcus amylolentus CBS 6039, Cryptococcus amylolentus CBS6039

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L202_00176	L202_00491	A0A1E3I667	A0A1E3I7M3	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	Nuclear protein localization protein 4.	0.568
L202_00176	L202_00901	A0A1E3I667	A0A1E3I8N4	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.423
L202_00176	L202_01101	A0A1E3I667	A0A1E3I2U9	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	UV excision repair protein Rad23.	0.668
L202_00176	L202_02402	A0A1E3I667	A0A1E3I0Q6	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	TPR_REGION domain-containing protein.	0.607
L202_00176	L202_02751	A0A1E3I667	A0A1E3HW46	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	U-box domain-containing protein.	0.593
L202_00176	L202_03525	A0A1E3I667	A0A1E3HTV5	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	HECT domain-containing protein.	0.500
L202_00176	L202_04265	A0A1E3I667	A0A1E3HQT7	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.746
L202_00176	L202_04325	A0A1E3I667	A0A1E3HQW7	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.712
L202_00176	L202_05484	A0A1E3I667	A0A1E3HKP0	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.812
L202_00176	L202_05563	A0A1E3I667	A0A1E3HKX9	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	RING-type domain-containing protein.	0.601
L202_00176	L202_07083	A0A1E3I667	A0A1E3HEJ5	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	RING-CH-type domain-containing protein.	0.527
L202_00491	L202_00176	A0A1E3I7M3	A0A1E3I667	Nuclear protein localization protein 4.	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	0.568
L202_00491	L202_00901	A0A1E3I7M3	A0A1E3I8N4	Nuclear protein localization protein 4.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.640
L202_00491	L202_01101	A0A1E3I7M3	A0A1E3I2U9	Nuclear protein localization protein 4.	UV excision repair protein Rad23.	0.851
L202_00491	L202_01156	A0A1E3I7M3	A0A1E3I3F9	Nuclear protein localization protein 4.	Uncharacterized protein.	0.653
L202_00491	L202_02751	A0A1E3I7M3	A0A1E3HW46	Nuclear protein localization protein 4.	U-box domain-containing protein.	0.955
L202_00491	L202_03199	A0A1E3I7M3	A0A1E3HZD9	Nuclear protein localization protein 4.	UAS domain-containing protein.	0.944
L202_00491	L202_03314	A0A1E3I7M3	A0A1E3HSL0	Nuclear protein localization protein 4.	Uncharacterized protein.	0.999
L202_00491	L202_03407	A0A1E3I7M3	A0A1E3HUJ5	Nuclear protein localization protein 4.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.952
L202_00491	L202_03409	A0A1E3I7M3	A0A1E3HST2	Nuclear protein localization protein 4.	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	0.998