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| | URM1 | Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...] (144 aa) |
| | L202_08190 | Uncharacterized protein; Belongs to the peptidase C19 family. (1015 aa) |
| | L202_07720 | Uncharacterized protein. (725 aa) |
| | L202_07805 | ANAPC4 domain-containing protein. (831 aa) |
| | L202_07787 | E3 ubiquitin protein ligase. (822 aa) |
| | L202_07845 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | L202_07838 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | L202_08007 | Uncharacterized protein. (470 aa) |
| | L202_08451 | RING-type domain-containing protein. (1042 aa) |
| | L202_07373 | RING-type domain-containing protein. (163 aa) |
| | L202_07400 | Uncharacterized protein. (783 aa) |
| | L202_07410 | RING-type domain-containing protein. (895 aa) |
| | L202_07951 | Uncharacterized protein. (3349 aa) |
| | L202_07504 | Uncharacterized protein. (588 aa) |
| | L202_07514 | E3 ubiquitin-protein ligase PEP5. (1070 aa) |
| | L202_07540 | ThiF domain-containing protein. (349 aa) |
| | L202_07585 | Uncharacterized protein. (948 aa) |
| | L202_08086 | Uncharacterized protein. (326 aa) |
| | L202_07659 | Uncharacterized protein. (889 aa) |
| | L202_06813 | Uncharacterized protein. (341 aa) |
| | L202_06840 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (236 aa) |
| | L202_06901 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (267 aa) |
| | L202_07511 | CULLIN_2 domain-containing protein; Belongs to the cullin family. (730 aa) |
| | L202_07035 | RING-type domain-containing protein. (723 aa) |
| | L202_07055 | MPN domain-containing protein. (367 aa) |
| | L202_07355 | USP domain-containing protein; Belongs to the peptidase C19 family. (649 aa) |
| | L202_07452 | OTU domain-containing protein. (326 aa) |
| | L202_07185 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (209 aa) |
| | L202_07657 | WD_REPEATS_REGION domain-containing protein. (1228 aa) |
| | L202_06400 | LisH domain-containing protein. (397 aa) |
| | L202_06442 | Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (275 aa) |
| | L202_06814 | PCI domain-containing protein. (482 aa) |
| | L202_06557 | RING-type domain-containing protein. (1640 aa) |
| | L202_06570 | Ubiquitin carboxyl-terminal hydrolase. (167 aa) |
| | L202_06569 | Uncharacterized protein. (166 aa) |
| | L202_06574 | Rhodanese domain-containing protein. (414 aa) |
| | L202_06942 | Ubiquitin-conjugating enzyme E2-16 kDa; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | L202_06648 | WD_REPEATS_REGION domain-containing protein. (648 aa) |
| | L202_06950 | Ubiquitin carboxyl-terminal hydrolase. (809 aa) |
| | L202_05762 | OTU domain-containing protein. (349 aa) |
| | L202_06724 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (659 aa) |
| | SUS1 | Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...] (99 aa) |
| | L202_06683 | WD_REPEATS_REGION domain-containing protein. (573 aa) |
| | L202_06154 | USP domain-containing protein; Belongs to the peptidase C19 family. (1018 aa) |
| | L202_06527 | Uncharacterized protein. (599 aa) |
| | L202_05228 | Uncharacterized protein. (684 aa) |
| | L202_05879 | Polyubiquitin-C, variant. (533 aa) |
| | L202_05484 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (251 aa) |
| | L202_05489 | Uncharacterized protein. (773 aa) |
| | L202_05563 | RING-type domain-containing protein. (750 aa) |
| | L202_05556 | Uncharacterized protein. (842 aa) |
| | L202_06053 | TIP120 domain-containing protein. (1264 aa) |
| | L202_05415 | BTB domain-containing protein. (324 aa) |
| | L202_05683 | Uncharacterized protein. (328 aa) |
| | L202_04582 | PCI domain-containing protein. (457 aa) |
| | L202_04597 | Uncharacterized protein. (682 aa) |
| | L202_04600 | CULLIN_2 domain-containing protein; Belongs to the cullin family. (841 aa) |
| | L202_05213 | RING-type domain-containing protein. (764 aa) |
| | L202_04648 | CULLIN_2 domain-containing protein; Belongs to the cullin family. (832 aa) |
| | L202_04666 | Ubiquitin carboxyl-terminal hydrolase. (483 aa) |
| | L202_04678 | USP domain-containing protein; Belongs to the peptidase C19 family. (1459 aa) |
| | L202_04737 | RING-type domain-containing protein. (667 aa) |
| | L202_04811 | Josephin domain-containing protein. (390 aa) |
| | L202_04763 | HECT domain-containing protein. (1961 aa) |
| | L202_05575 | RING-type domain-containing protein. (431 aa) |
| | L202_05055 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (571 aa) |
| | L202_05113 | Uncharacterized protein. (692 aa) |
| | L202_04580 | CULLIN_2 domain-containing protein; Belongs to the cullin family. (841 aa) |
| | L202_05714 | E3 ubiquitin-protein ligase. (828 aa) |
| | L202_03944 | PCI domain-containing protein. (540 aa) |
| | L202_03960 | Uncharacterized protein. (972 aa) |
| | L202_04107 | USP domain-containing protein; Belongs to the peptidase C19 family. (898 aa) |
| | L202_04158 | SAGA-associated factor 11. (323 aa) |
| | L202_04797 | Uncharacterized protein. (642 aa) |
| | L202_04236 | Uncharacterized protein. (627 aa) |
| | L202_04265 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (175 aa) |
| | L202_04325 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (311 aa) |
| | L202_04337 | RING-type domain-containing protein. (568 aa) |
| | L202_04335 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1885 aa) |
| | L202_04359 | Uncharacterized protein. (207 aa) |
| | L202_04401 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (167 aa) |
| | NCS6 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (368 aa) |
| | L202_04434 | Uncharacterized protein. (440 aa) |
| | L202_04292 | APC1_C domain-containing protein. (1968 aa) |
| | L202_04517 | Zf-rbx1 domain-containing protein. (466 aa) |
| | L202_04518 | Uncharacterized protein. (855 aa) |
| | L202_04529 | RING-type domain-containing protein. (620 aa) |
| | L202_04092 | Uncharacterized protein. (343 aa) |
| | L202_04539 | RING-type domain-containing protein. (805 aa) |
| | L202_03389 | Uncharacterized protein. (369 aa) |
| | L202_03390 | Uncharacterized protein. (183 aa) |
| | L202_04381 | TPR_REGION domain-containing protein. (801 aa) |
| | L202_04323 | RING-type domain-containing protein. (1818 aa) |
| | L202_03594 | NEDD8-conjugating enzyme UBC12; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | L202_04361 | Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (167 aa) |
| | L202_03658 | Uncharacterized protein. (89 aa) |
| | L202_03525 | HECT domain-containing protein. (1053 aa) |
| | L202_03696 | CTLH domain-containing protein. (425 aa) |
| | L202_03724 | MPN domain-containing protein. (309 aa) |
| | L202_03711 | Pex2_Pex12 domain-containing protein. (401 aa) |
| | L202_03690 | USP domain-containing protein. (753 aa) |
| | L202_03761 | UBA_e1_C domain-containing protein. (1014 aa) |
| | L202_03818 | Histone chaperone ASF1. (205 aa) |
| | L202_03445 | COP9 signalosome complex subunit 5. (366 aa) |
| | L202_03682 | USP domain-containing protein; Belongs to the peptidase C19 family. (1437 aa) |
| | L202_02751 | U-box domain-containing protein. (1160 aa) |
| | L202_02685 | ULP_PROTEASE domain-containing protein. (1647 aa) |
| | L202_02705 | ULP_PROTEASE domain-containing protein. (505 aa) |
| | L202_02819 | ANAPC5 domain-containing protein. (779 aa) |
| | L202_02948 | RING-type domain-containing protein. (360 aa) |
| | L202_02958 | DNA repair protein rad18. (355 aa) |
| | L202_02850 | Uncharacterized protein; Belongs to the peptidase C19 family. (1163 aa) |
| | L202_03054 | Uncharacterized protein. (1023 aa) |
| | L202_03112 | GLTSCR1 domain-containing protein. (489 aa) |
| | L202_03127 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (151 aa) |
| | L202_03244 | Uncharacterized protein. (287 aa) |
| | L202_03133 | Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family. (651 aa) |
| | L202_01962 | RBR-type E3 ubiquitin transferase. (524 aa) |
| | L202_02002 | Polyubiquitin. (988 aa) |
| | L202_02006 | Uncharacterized protein. (572 aa) |
| | L202_02096 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (135 aa) |
| | L202_03227 | RING-type domain-containing protein. (681 aa) |
| | L202_02111 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (603 aa) |
| | L202_02112 | SP-RING-type domain-containing protein. (327 aa) |
| | L202_02184 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (257 aa) |
| | L202_02193 | Helicase ATP-binding domain-containing protein. (1224 aa) |
| | L202_02281 | Uncharacterized protein. (420 aa) |
| | L202_02328 | Ubiquitin-60S ribosomal protein L40. (164 aa) |
| | L202_02371 | USP domain-containing protein; Belongs to the peptidase C19 family. (472 aa) |
| | L202_02502 | Ubiquitin-conjugating enzyme E2 8; Belongs to the ubiquitin-conjugating enzyme family. (232 aa) |
| | L202_02032 | Uncharacterized protein. (860 aa) |
| | L202_02534 | Peptidyl-prolyl cis-trans isomerase-like 2. (589 aa) |
| | L202_02365 | Uncharacterized protein. (764 aa) |
| | L202_02060 | Ubiquitin-like domain-containing protein. (158 aa) |
| | L202_00945 | Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (167 aa) |
| | L202_01012 | USP domain-containing protein; Belongs to the peptidase C19 family. (1378 aa) |
| | L202_01127 | Uncharacterized protein; Belongs to the SKP1 family. (168 aa) |
| | L202_01226 | YDG domain-containing protein. (330 aa) |
| | L202_01167 | Uncharacterized protein. (1022 aa) |
| | L202_01333 | RING-box protein 1A. (105 aa) |
| | L202_01284 | E2_bind domain-containing protein. (431 aa) |
| | L202_01316 | RING-type domain-containing protein. (559 aa) |
| | L202_01375 | RING-type domain-containing protein. (866 aa) |
| | L202_01069 | RING-type domain-containing protein. (1338 aa) |
| | L202_01678 | Uncharacterized protein. (939 aa) |
| | L202_01169 | Urb2 domain-containing protein. (1303 aa) |
| | L202_01851 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (141 aa) |
| | L202_01813 | CULLIN_2 domain-containing protein; Belongs to the cullin family. (703 aa) |
| | L202_01755 | RING-type domain-containing protein. (814 aa) |
| | L202_01342 | RING-type domain-containing protein. (287 aa) |
| | L202_01429 | Uncharacterized protein. (1440 aa) |
| | L202_01412 | USP domain-containing protein; Belongs to the peptidase C19 family. (946 aa) |
| | L202_00007 | Pex2_Pex12 domain-containing protein. (421 aa) |
| | L202_00176 | Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family. (223 aa) |
| | L202_00129 | RING-type domain-containing protein. (841 aa) |
| | L202_00217 | CIA30 domain-containing protein. (281 aa) |
| | NCS2 | Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (525 aa) |
| | L202_00490 | RBR-type E3 ubiquitin transferase. (574 aa) |
| | L202_00617 | Uncharacterized protein. (306 aa) |
| | L202_00508 | OTU domain-containing protein. (583 aa) |
| | L202_00541 | Uncharacterized protein. (252 aa) |
| | L202_00492 | Uncharacterized protein. (520 aa) |
| | L202_00005 | UCH domain-containing protein. (775 aa) |
| | L202_00031 | Ubiquitin-like domain-containing protein. (101 aa) |
| | L202_00677 | Uncharacterized protein. (445 aa) |
| | L202_00803 | Uncharacterized protein. (792 aa) |
| | L202_00795 | Uncharacterized protein. (948 aa) |
| | L202_00231 | Uncharacterized protein. (622 aa) |
| | L202_00260 | Uncharacterized protein. (553 aa) |
| | L202_00848 | RING-type domain-containing protein. (601 aa) |
| | L202_00315 | Ubiquitin-like domain-containing protein. (78 aa) |
| | L202_00846 | Uncharacterized protein. (470 aa) |
| | L202_00629 | Uncharacterized protein. (502 aa) |
