(35 nodes) Recognition of DNA damage by PCNA-containing replication complex network (Cryptococcus amylolentus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	L202_04107	USP domain-containing protein; Belongs to the peptidase C19 family. (898 aa)
	L202_04479	Uncharacterized protein. (543 aa)
	L202_03688	AAA domain-containing protein. (978 aa)
	L202_02656	Uncharacterized protein. (224 aa)
	L202_02865	Uncharacterized protein. (189 aa)
	L202_02958	DNA repair protein rad18. (355 aa)
	L202_03055	Uncharacterized protein. (517 aa)
	L202_02002	Polyubiquitin. (988 aa)
	L202_02111	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (603 aa)
	L202_02478	Uncharacterized protein. (284 aa)
	L202_02564	Uncharacterized protein. (129 aa)
	L202_02060	Ubiquitin-like domain-containing protein. (158 aa)
	L202_02086	Uncharacterized protein. (290 aa)
	L202_00945	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
	L202_01333	RING-box protein 1A. (105 aa)
	L202_01852	Uncharacterized protein. (479 aa)
	L202_01349	Uncharacterized protein. (108 aa)
	L202_00021	Uncharacterized protein. (506 aa)
	L202_00217	CIA30 domain-containing protein. (281 aa)
	L202_08195	DUF4939 domain-containing protein. (470 aa)
	L202_08370	CCHC-type domain-containing protein. (623 aa)
	L202_08459	Uncharacterized protein. (354 aa)
	L202_07681	Amino_oxidase domain-containing protein. (509 aa)
	L202_07744	Uncharacterized protein. (354 aa)
	L202_07426	CCHC-type domain-containing protein. (372 aa)
	L202_06876	CPSF_A domain-containing protein. (1279 aa)
	L202_07657	WD_REPEATS_REGION domain-containing protein. (1228 aa)
	L202_06648	WD_REPEATS_REGION domain-containing protein. (648 aa)
	L202_06608	CCHC-type domain-containing protein. (609 aa)
	L202_05879	Polyubiquitin-C, variant. (533 aa)
	L202_05432	Uncharacterized protein. (248 aa)
	L202_05494	Zds_C domain-containing protein. (1065 aa)
	L202_04600	CULLIN_2 domain-containing protein; Belongs to the cullin family. (841 aa)
	L202_04701	CBFD_NFYB_HMF domain-containing protein. (274 aa)
	L202_04580	CULLIN_2 domain-containing protein; Belongs to the cullin family. (841 aa)

Your Current Organism:

Cryptococcus amylolentus

NCBI taxonomy Id: 1295533
Other names: C. amylolentus CBS 6039, Cryptococcus amylolentus CBS 6039, Cryptococcus amylolentus CBS6039

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L202_00021	L202_00217	A0A1E3I6K9	A0A1E3I6V1	Uncharacterized protein.	CIA30 domain-containing protein.	0.583
L202_00021	L202_00945	A0A1E3I6K9	A0A1E3I2B6	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.	0.627
L202_00021	L202_01333	A0A1E3I6K9	A0A1E3I3A3	Uncharacterized protein.	RING-box protein 1A.	0.621
L202_00021	L202_02002	A0A1E3I6K9	A0A1E3HZ29	Uncharacterized protein.	Polyubiquitin.	0.592
L202_00021	L202_02060	A0A1E3I6K9	A0A1E3I1G2	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.583
L202_00021	L202_02111	A0A1E3I6K9	A0A1E3HZL2	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.588
L202_00021	L202_02865	A0A1E3I6K9	A0A1E3HWM9	Uncharacterized protein.	Uncharacterized protein.	0.801
L202_00021	L202_02958	A0A1E3I6K9	A0A1E3HWV7	Uncharacterized protein.	DNA repair protein rad18.	0.662
L202_00021	L202_05879	A0A1E3I6K9	A0A1E3HKA8	Uncharacterized protein.	Polyubiquitin-C, variant.	0.592
L202_00021	L202_06648	A0A1E3I6K9	A0A1E3HGQ0	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.629
L202_00021	L202_06876	A0A1E3I6K9	A0A1E3HEC2	Uncharacterized protein.	CPSF_A domain-containing protein.	0.635
L202_00217	L202_00021	A0A1E3I6V1	A0A1E3I6K9	CIA30 domain-containing protein.	Uncharacterized protein.	0.583
L202_00217	L202_00945	A0A1E3I6V1	A0A1E3I2B6	CIA30 domain-containing protein.	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.	0.920
L202_00217	L202_01333	A0A1E3I6V1	A0A1E3I3A3	CIA30 domain-containing protein.	RING-box protein 1A.	0.911
L202_00217	L202_01349	A0A1E3I6V1	A0A1E3I5Q7	CIA30 domain-containing protein.	Uncharacterized protein.	0.448
L202_00217	L202_01852	A0A1E3I6V1	A0A1E3I523	CIA30 domain-containing protein.	Uncharacterized protein.	0.448
L202_00217	L202_02002	A0A1E3I6V1	A0A1E3HZ29	CIA30 domain-containing protein.	Polyubiquitin.	0.908
L202_00217	L202_02086	A0A1E3I6V1	A0A1E3I1J3	CIA30 domain-containing protein.	Uncharacterized protein.	0.448
L202_00217	L202_02111	A0A1E3I6V1	A0A1E3HZL2	CIA30 domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.623
L202_00217	L202_02478	A0A1E3I6V1	A0A1E3I104	CIA30 domain-containing protein.	Uncharacterized protein.	0.448