(174 nodes) DNA repair, and Activation of the pre-replicative complex network (Atta cephalotes)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	A0A158N8V5	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (567 aa)
	A0A158N8Y4	Uncharacterized protein. (541 aa)
	A0A158N8Y5	Uncharacterized protein. (561 aa)
	A0A158N8Y6	Uncharacterized protein. (555 aa)
	A0A158N982	Uncharacterized protein. (562 aa)
	A0A158N983	Uncharacterized protein. (551 aa)
	A0A158N984	zf-CCHH domain-containing protein. (681 aa)
	A0A158N9C7	Uncharacterized protein. (1044 aa)
	A0A158N9D0	DNA polymerase. (1092 aa)
	A0A158N9J8	Uncharacterized protein. (200 aa)
	A0A158N9W1	Uncharacterized protein. (1541 aa)
	A0A158NA02	Uncharacterized protein. (234 aa)
	A0A158NA26	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (337 aa)
	A0A158NA76	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2243 aa)
	A0A158NA90	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (362 aa)
	A0A158NAF4	DNA helicase; Belongs to the MCM family. (734 aa)
	A0A158NAH5	ENDO3c domain-containing protein. (324 aa)
	A0A158NAI4	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (521 aa)
	A0A158NAL0	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	A0A158NAS2	Uncharacterized protein. (217 aa)
	A0A158NAS3	Uncharacterized protein. (154 aa)
	A0A158NAS4	MutL_C domain-containing protein. (179 aa)
	A0A158NB18	DRMBL domain-containing protein. (360 aa)
	A0A158NB58	ORC_WH_C domain-containing protein. (657 aa)
	A0A158NBJ9	WD_REPEATS_REGION domain-containing protein. (932 aa)
	A0A158NC88	Sld5 domain-containing protein. (202 aa)
	A0A158NCB2	AAA domain-containing protein. (354 aa)
	A0A158NCF3	Uncharacterized protein. (1855 aa)
	A0A158NCJ6	Uncharacterized protein. (270 aa)
	A0A158NCX1	DNA polymerase. (1942 aa)
	A0A158ND01	Piezo-type mechanosensitive ion channel component. (2572 aa)
	A0A158ND29	MCM domain-containing protein; Belongs to the MCM family. (626 aa)
	A0A158ND76	Uncharacterized protein. (458 aa)
	A0A158NDI3	CDT1 domain-containing protein. (443 aa)
	A0A158NDY3	Uncharacterized protein. (114 aa)
	A0A158NE72	DNA_MISMATCH_REPAIR_2 domain-containing protein. (660 aa)
	A0A158NED4	Uncharacterized protein. (1065 aa)
	A0A158NEJ2	TP6A_N domain-containing protein. (419 aa)
	A0A158NEQ3	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (3698 aa)
	A0A158NEQ8	DNA ligase. (976 aa)
	A0A158NF12	RECA_2 domain-containing protein. (321 aa)
	A0A158NF17	Uncharacterized protein. (1267 aa)
	A0A158NF22	NTF2 domain-containing protein. (130 aa)
	Fen1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (381 aa)
	A0A158NFG0	Uncharacterized protein. (423 aa)
	A0A158NFI1	Checkpoint protein; Belongs to the HUS1 family. (275 aa)
	A0A158NFQ4	Uncharacterized protein. (672 aa)
	A0A158NG68	Enkurin domain-containing protein. (391 aa)
	A0A158NG92	DNA_binding_1 domain-containing protein. (193 aa)
	A0A158NGE9	DNA helicase; Belongs to the MCM family. (893 aa)
	A0A158NGJ7	Uncharacterized protein. (198 aa)
	A0A158NGQ4	Uncharacterized protein. (469 aa)
	A0A158NGT7	Uncharacterized protein. (965 aa)
	A0A158NGW1	SAE2 domain-containing protein. (530 aa)
	A0A158NGW6	BRCT domain-containing protein. (487 aa)
	A0A158NH93	Uncharacterized protein. (1447 aa)
	A0A158NHB2	ERCC4 domain-containing protein. (453 aa)
	A0A158NHD5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (966 aa)
	A0A158NHN9	Uncharacterized protein. (518 aa)
	A0A158NHS6	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (340 aa)
	A0A158NHT5	Uncharacterized protein. (447 aa)
	A0A158NHW7	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (608 aa)
	A0A158NI06	Uncharacterized protein. (507 aa)
	A0A158NI10	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (573 aa)
	NTH1	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (342 aa)
	A0A158NIA9	zf-C2HE domain-containing protein. (117 aa)
	A0A158NIC0	Uncharacterized protein. (860 aa)
	A0A158NIF0	Sld5 domain-containing protein. (194 aa)
	A0A158NIG0	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (268 aa)
	A0A158NIV2	Uncharacterized protein. (903 aa)
	A0A158NJ90	Uncharacterized protein. (174 aa)
	A0A158NK03	Uncharacterized protein. (118 aa)
	A0A158NK54	Uncharacterized protein. (1235 aa)
	A0A158NK63	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1105 aa)
	A0A158NKL2	Uncharacterized protein. (722 aa)
	A0A158NKW1	Ku domain-containing protein. (566 aa)
	A0A158NKZ0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (471 aa)
	A0A158NKZ4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (724 aa)
	A0A158NL65	Uncharacterized protein. (1521 aa)
	A0A158NLA0	Uncharacterized protein. (580 aa)
	A0A158NLB5	Uncharacterized protein. (1200 aa)
	A0A158NLC7	RECA_2 domain-containing protein. (255 aa)
	A0A158NLF2	Rep_fac_C domain-containing protein. (346 aa)
	A0A158NLM0	Uncharacterized protein. (675 aa)
	A0A158NLP0	MCM domain-containing protein; Belongs to the MCM family. (735 aa)
	A0A158NLR0	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (568 aa)
	A0A158NLS9	FHA_2 domain-containing protein. (562 aa)
	A0A158NLU6	AAA domain-containing protein. (356 aa)
	A0A158NM71	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (561 aa)
	A0A158NMA8	Uncharacterized protein. (848 aa)
	A0A158NMB1	Uncharacterized protein. (1413 aa)
	A0A158NME5	Non-specific serine/threonine protein kinase. (2888 aa)
	A0A158NMR3	DNA helicase; Belongs to the MCM family. (808 aa)
	A0A158NMW9	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (216 aa)
	A0A158NMX6	Uncharacterized protein. (554 aa)
	A0A158NN14	Uncharacterized protein. (1343 aa)
	A0A158NNB6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (389 aa)
	A0A158NNR0	Tower domain-containing protein. (1646 aa)
	A0A158NNS8	Uncharacterized protein. (908 aa)
	A0A158NP77	WD_REPEATS_REGION domain-containing protein. (683 aa)
	A0A158NPA7	Uncharacterized protein. (533 aa)
	A0A158NPK9	UmuC domain-containing protein. (817 aa)
	A0A158NQK9	RPA_C domain-containing protein. (241 aa)
	A0A158NQL1	Uncharacterized protein. (290 aa)
	A0A158NS59	Uncharacterized protein. (247 aa)
	A0A158NS73	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2428 aa)
	A0A158NSA3	AAA domain-containing protein. (1147 aa)
	A0A158NSK1	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1122 aa)
	A0A158NSL7	3'-5' exonuclease domain-containing protein. (612 aa)
	A0A158NSN9	Uncharacterized protein. (1114 aa)
	A0A158NT24	DNA helicase. (823 aa)
	A0A158NT44	Uncharacterized protein. (397 aa)
	A0A158NTJ1	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (322 aa)
	A0A158NTL4	AAA domain-containing protein. (328 aa)
	A0A158NTP1	Uncharacterized protein. (501 aa)
	A0A158NTR6	AAA domain-containing protein. (931 aa)
	A0A158NTT4	Uncharacterized protein. (360 aa)
	A0A158NTU3	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1131 aa)
	A0A158NTX6	HORMA domain-containing protein. (205 aa)
	A0A158NTY4	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (417 aa)
	A0A158NUV6	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (627 aa)
	A0A158NUY9	Uncharacterized protein. (471 aa)
	A0A158NVK9	Uncharacterized protein. (766 aa)
	A0A158NVT2	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (206 aa)
	A0A158NW05	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (617 aa)
	A0A158NW11	Uncharacterized protein. (300 aa)
	A0A158NW56	Uncharacterized protein. (1251 aa)
	A0A158NWB2	XPA_C domain-containing protein. (271 aa)
	A0A158NWB9	Uncharacterized protein. (416 aa)
	A0A158NWG2	Uncharacterized protein. (584 aa)
	A0A158NWI9	Uncharacterized protein. (166 aa)
	A0A158NWN0	MutS_II domain-containing protein; Belongs to the actin family. (407 aa)
	A0A158NWP4	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (149 aa)
	A0A158NXB8	Uncharacterized protein. (782 aa)
	A0A158NXD6	Uncharacterized protein. (274 aa)
	A0A158NXV4	Uncharacterized protein. (408 aa)
	A0A158NXW4	DUF1767 domain-containing protein. (596 aa)
	A0A158NY19	Uncharacterized protein. (1477 aa)
	A0A158NY25	Uncharacterized protein. (436 aa)
	A0A158NY48	ERCC4 domain-containing protein. (1031 aa)
	A0A158NYA2	Replication factor C subunit 1. (1010 aa)
	A0A158NYC1	3'-5' exonuclease domain-containing protein. (263 aa)
	A0A158NYH5	Uncharacterized protein. (1334 aa)
	A0A158NYJ2	DNA helicase; Belongs to the MCM family. (902 aa)
	A0A158NYL9	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (626 aa)
	A0A158NYU3	Uncharacterized protein. (744 aa)
	A0A158NYZ2	CBFD_NFYB_HMF domain-containing protein. (131 aa)
	A0A158NZ02	ERCC4 domain-containing protein. (436 aa)
	A0A158NZ22	Zinc-hook domain-containing protein. (1369 aa)
	A0A158NZ43	Uncharacterized protein. (440 aa)
	A0A158NZE8	Uncharacterized protein. (322 aa)
	A0A158NZK4	Uncharacterized protein. (693 aa)
	A0A158NZS5	Helicase ATP-binding domain-containing protein. (950 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (622 aa)
	A0A158P0T6	DNA_mis_repair domain-containing protein. (764 aa)
	A0A158P125	Mcm10 domain-containing protein. (738 aa)
	A0A158P1A0	Ubiquitin-like domain-containing protein. (313 aa)
	A0A158P1D7	USP domain-containing protein; Belongs to the peptidase C19 family. (641 aa)
	A0A158P1I5	Uncharacterized protein. (392 aa)
	A0A158P1W4	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (191 aa)
	A0A158P222	TNFR-Cys domain-containing protein. (339 aa)
	A0A158P247	DNA polymerase. (1472 aa)
	A0A158P2A2	DBF4-type domain-containing protein. (1577 aa)
	A0A158P2A5	Uncharacterized protein. (273 aa)
	A0A158P2Y5	Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (451 aa)
	A0A158P2Z0	CBFD_NFYB_HMF domain-containing protein. (127 aa)
	A0A158P3C0	Helicase ATP-binding domain-containing protein. (1153 aa)
	A0A158P3D6	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (902 aa)
	A0A158P3L5	UmuC domain-containing protein. (576 aa)
	A0A158P3P5	Uncharacterized protein. (784 aa)
	A0A158P3W2	Uncharacterized protein. (566 aa)
	A0A158P3X4	HMG box domain-containing protein. (746 aa)
	A0A158P3Z2	Rad51 domain-containing protein. (268 aa)
	A0A158P450	Uncharacterized protein. (1001 aa)

Your Current Organism:

Atta cephalotes

NCBI taxonomy Id: 12957
Other names: A. cephalotes

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A158N8V5	A0A158N9D0	A0A158N8V5	A0A158N9D0	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	DNA polymerase.	0.886
A0A158N8V5	A0A158NA76	A0A158N8V5	A0A158NA76	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.898
A0A158N8V5	A0A158NAF4	A0A158N8V5	A0A158NAF4	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	DNA helicase; Belongs to the MCM family.	0.812
A0A158N8V5	A0A158NAI4	A0A158N8V5	A0A158NAI4	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.879
A0A158N8V5	A0A158NAL0	A0A158N8V5	A0A158NAL0	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.830
A0A158N8V5	A0A158NB58	A0A158N8V5	A0A158NB58	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	ORC_WH_C domain-containing protein.	0.489
A0A158N8V5	A0A158NBJ9	A0A158N8V5	A0A158NBJ9	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	WD_REPEATS_REGION domain-containing protein.	0.780
A0A158N8V5	A0A158NCB2	A0A158N8V5	A0A158NCB2	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	AAA domain-containing protein.	0.727
A0A158N8V5	A0A158NCX1	A0A158N8V5	A0A158NCX1	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	DNA polymerase.	0.822
A0A158N8V5	A0A158ND29	A0A158N8V5	A0A158ND29	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	MCM domain-containing protein; Belongs to the MCM family.	0.722
A0A158N8V5	A0A158ND76	A0A158N8V5	A0A158ND76	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	Uncharacterized protein.	0.717
A0A158N8V5	A0A158NDI3	A0A158N8V5	A0A158NDI3	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	CDT1 domain-containing protein.	0.498
A0A158N8V5	A0A158NDY3	A0A158N8V5	A0A158NDY3	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	Uncharacterized protein.	0.470
A0A158N8V5	A0A158NEQ8	A0A158N8V5	A0A158NEQ8	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	DNA ligase.	0.430
A0A158N8V5	A0A158NFG0	A0A158N8V5	A0A158NFG0	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	Uncharacterized protein.	0.918
A0A158N8V5	A0A158NGE9	A0A158N8V5	A0A158NGE9	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	DNA helicase; Belongs to the MCM family.	0.845
A0A158N8V5	A0A158NHT5	A0A158N8V5	A0A158NHT5	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	Uncharacterized protein.	0.717
A0A158N8V5	A0A158NHW7	A0A158N8V5	A0A158NHW7	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.619
A0A158N8V5	A0A158NI10	A0A158N8V5	A0A158NI10	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.961
A0A158N8V5	A0A158NK03	A0A158N8V5	A0A158NK03	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	Uncharacterized protein.	0.419

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