(27 nodes) Homologous DNA Pairing and Strand Exchange, and Removal of the Flap Intermediate network (Atta cephalotes)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A158NCF3	Uncharacterized protein. (1855 aa)
	A0A158NCJ6	Uncharacterized protein. (270 aa)
	A0A158NDY3	Uncharacterized protein. (114 aa)
	A0A158NF12	RECA_2 domain-containing protein. (321 aa)
	A0A158NGW1	SAE2 domain-containing protein. (530 aa)
	A0A158NHD5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (966 aa)
	A0A158NHS6	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (340 aa)
	A0A158NHW7	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (608 aa)
	A0A158NI06	Uncharacterized protein. (507 aa)
	A0A158NK54	Uncharacterized protein. (1235 aa)
	A0A158NK63	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1105 aa)
	A0A158NL65	Uncharacterized protein. (1521 aa)
	A0A158NLC7	RECA_2 domain-containing protein. (255 aa)
	A0A158NNR0	Tower domain-containing protein. (1646 aa)
	A0A158NQK9	RPA_C domain-containing protein. (241 aa)
	A0A158NQL1	Uncharacterized protein. (290 aa)
	A0A158NUV6	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (627 aa)
	A0A158NW56	Uncharacterized protein. (1251 aa)
	A0A158NWB9	Uncharacterized protein. (416 aa)
	A0A158NXW4	DUF1767 domain-containing protein. (596 aa)
	A0A158NYL9	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (626 aa)
	A0A158NZ22	Zinc-hook domain-containing protein. (1369 aa)
	A0A158NZK4	Uncharacterized protein. (693 aa)
	A0A158NZS5	Helicase ATP-binding domain-containing protein. (950 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (622 aa)
	A0A158P3P5	Uncharacterized protein. (784 aa)
	A0A158P3Z2	Rad51 domain-containing protein. (268 aa)

Your Current Organism:

Atta cephalotes

NCBI taxonomy Id: 12957
Other names: A. cephalotes

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A158NCF3	A0A158NCJ6	A0A158NCF3	A0A158NCJ6	Uncharacterized protein.	Uncharacterized protein.	0.762
A0A158NCF3	A0A158NDY3	A0A158NCF3	A0A158NDY3	Uncharacterized protein.	Uncharacterized protein.	0.455
A0A158NCF3	A0A158NF12	A0A158NCF3	A0A158NF12	Uncharacterized protein.	RECA_2 domain-containing protein.	0.738
A0A158NCF3	A0A158NGW1	A0A158NCF3	A0A158NGW1	Uncharacterized protein.	SAE2 domain-containing protein.	0.999
A0A158NCF3	A0A158NHD5	A0A158NCF3	A0A158NHD5	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.461
A0A158NCF3	A0A158NHS6	A0A158NCF3	A0A158NHS6	Uncharacterized protein.	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.	0.977
A0A158NCF3	A0A158NHW7	A0A158NCF3	A0A158NHW7	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.717
A0A158NCF3	A0A158NI06	A0A158NCF3	A0A158NI06	Uncharacterized protein.	Uncharacterized protein.	0.911
A0A158NCF3	A0A158NK54	A0A158NCF3	A0A158NK54	Uncharacterized protein.	Uncharacterized protein.	0.764
A0A158NCF3	A0A158NK63	A0A158NCF3	A0A158NK63	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.573
A0A158NCF3	A0A158NL65	A0A158NCF3	A0A158NL65	Uncharacterized protein.	Uncharacterized protein.	0.584
A0A158NCF3	A0A158NLC7	A0A158NCF3	A0A158NLC7	Uncharacterized protein.	RECA_2 domain-containing protein.	0.744
A0A158NCF3	A0A158NNR0	A0A158NCF3	A0A158NNR0	Uncharacterized protein.	Tower domain-containing protein.	0.996
A0A158NCF3	A0A158NW56	A0A158NCF3	A0A158NW56	Uncharacterized protein.	Uncharacterized protein.	0.793
A0A158NCF3	A0A158NWB9	A0A158NCF3	A0A158NWB9	Uncharacterized protein.	Uncharacterized protein.	0.401
A0A158NCF3	A0A158NXW4	A0A158NCF3	A0A158NXW4	Uncharacterized protein.	DUF1767 domain-containing protein.	0.641
A0A158NCF3	A0A158NYL9	A0A158NCF3	A0A158NYL9	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.987
A0A158NCF3	A0A158NZ22	A0A158NCF3	A0A158NZ22	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.885
A0A158NCF3	A0A158NZS5	A0A158NCF3	A0A158NZS5	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.985
A0A158NCF3	A0A158P3P5	A0A158NCF3	A0A158P3P5	Uncharacterized protein.	Uncharacterized protein.	0.982