(11 nodes) HDR through Single Strand Annealing (SSA), and AAA domain network (Atta cephalotes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A158NCJ6	Uncharacterized protein. (270 aa)
	A0A158NDY3	Uncharacterized protein. (114 aa)
	A0A158NHW7	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (608 aa)
	A0A158NK54	Uncharacterized protein. (1235 aa)
	A0A158NK63	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1105 aa)
	A0A158NL65	Uncharacterized protein. (1521 aa)
	A0A158NQK9	RPA_C domain-containing protein. (241 aa)
	A0A158NW56	Uncharacterized protein. (1251 aa)
	A0A158NWB9	Uncharacterized protein. (416 aa)
	A0A158NXW4	DUF1767 domain-containing protein. (596 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (622 aa)

Your Current Organism:

Atta cephalotes

NCBI taxonomy Id: 12957
Other names: A. cephalotes

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A158NCJ6	A0A158NDY3	A0A158NCJ6	A0A158NDY3	Uncharacterized protein.	Uncharacterized protein.	0.972
A0A158NCJ6	A0A158NHW7	A0A158NCJ6	A0A158NHW7	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.997
A0A158NCJ6	A0A158NK54	A0A158NCJ6	A0A158NK54	Uncharacterized protein.	Uncharacterized protein.	0.885
A0A158NCJ6	A0A158NK63	A0A158NCJ6	A0A158NK63	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.837
A0A158NCJ6	A0A158NL65	A0A158NCJ6	A0A158NL65	Uncharacterized protein.	Uncharacterized protein.	0.891
A0A158NCJ6	A0A158NQK9	A0A158NCJ6	A0A158NQK9	Uncharacterized protein.	RPA_C domain-containing protein.	0.886
A0A158NCJ6	A0A158NW56	A0A158NCJ6	A0A158NW56	Uncharacterized protein.	Uncharacterized protein.	0.909
A0A158NCJ6	A0A158NWB9	A0A158NCJ6	A0A158NWB9	Uncharacterized protein.	Uncharacterized protein.	0.913
A0A158NCJ6	A0A158NXW4	A0A158NCJ6	A0A158NXW4	Uncharacterized protein.	DUF1767 domain-containing protein.	0.728
A0A158NCJ6	PIF1	A0A158NCJ6	A0A158P0R4	Uncharacterized protein.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	0.850
A0A158NDY3	A0A158NCJ6	A0A158NDY3	A0A158NCJ6	Uncharacterized protein.	Uncharacterized protein.	0.972
A0A158NDY3	A0A158NHW7	A0A158NDY3	A0A158NHW7	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.998
A0A158NDY3	A0A158NK54	A0A158NDY3	A0A158NK54	Uncharacterized protein.	Uncharacterized protein.	0.669
A0A158NDY3	A0A158NK63	A0A158NDY3	A0A158NK63	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.997
A0A158NDY3	A0A158NL65	A0A158NDY3	A0A158NL65	Uncharacterized protein.	Uncharacterized protein.	0.750
A0A158NDY3	A0A158NQK9	A0A158NDY3	A0A158NQK9	Uncharacterized protein.	RPA_C domain-containing protein.	0.992
A0A158NDY3	A0A158NW56	A0A158NDY3	A0A158NW56	Uncharacterized protein.	Uncharacterized protein.	0.996
A0A158NDY3	A0A158NWB9	A0A158NDY3	A0A158NWB9	Uncharacterized protein.	Uncharacterized protein.	0.919
A0A158NDY3	A0A158NXW4	A0A158NDY3	A0A158NXW4	Uncharacterized protein.	DUF1767 domain-containing protein.	0.996
A0A158NDY3	PIF1	A0A158NDY3	A0A158P0R4	Uncharacterized protein.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	0.782