(84 nodes) Mixed, incl. Regulation of actin dynamics for phagocytic cup formation, and CDC42 GTPase cycle network (Atta cephalotes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A158N932	Uncharacterized protein. (475 aa)
	A0A158N943	Uncharacterized protein. (638 aa)
	A0A158NDB8	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (368 aa)
	A0A158NDR9	Transgelin; Belongs to the calponin family. (188 aa)
	A0A158NDX7	BHLH domain-containing protein. (2400 aa)
	A0A158NE73	F-box domain-containing protein. (338 aa)
	A0A158NEC6	Uncharacterized protein. (1094 aa)
	A0A158NEF1	WH2 domain-containing protein. (595 aa)
	A0A158NEL8	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1291 aa)
	A0A158NEN1	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2301 aa)
	A0A158NFW0	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (160 aa)
	A0A158NGD4	Adenylyl cyclase-associated protein; Belongs to the CAP family. (915 aa)
	A0A158NGD5	Uncharacterized protein. (169 aa)
	A0A158NGD6	Uncharacterized protein. (430 aa)
	A0A158NHK5	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	A0A158NHY3	LIM zinc-binding domain-containing protein. (812 aa)
	A0A158NI22	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1010 aa)
	A0A158NI52	Uncharacterized protein. (191 aa)
	A0A158NID7	Urb2 domain-containing protein. (1223 aa)
	A0A158NIF2	Uncharacterized protein. (1546 aa)
	A0A158NIP0	SH3 domain-containing protein. (473 aa)
	A0A158NIU2	Uncharacterized protein. (1087 aa)
	A0A158NIZ6	Uncharacterized protein. (1199 aa)
	A0A158NJD7	Uncharacterized protein. (471 aa)
	A0A158NJF7	Uncharacterized protein. (3063 aa)
	A0A158NJL5	Rho-GAP domain-containing protein. (897 aa)
	A0A158NKA8	BAR domain-containing protein. (266 aa)
	A0A158NKD5	Uncharacterized protein. (1193 aa)
	A0A158NKH8	WH2 domain-containing protein. (444 aa)
	A0A158NKK1	Uncharacterized protein. (187 aa)
	A0A158NKY9	Non-specific serine/threonine protein kinase. (586 aa)
	A0A158NL62	Uncharacterized protein. (1756 aa)
	A0A158NLB8	Uncharacterized protein. (76 aa)
	A0A158NLU4	HP domain-containing protein. (814 aa)
	A0A158NMI2	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1142 aa)
	A0A158NMS9	Uncharacterized protein. (1122 aa)
	A0A158NMV6	Uncharacterized protein. (523 aa)
	A0A158NN34	Uncharacterized protein. (961 aa)
	A0A158NNA5	Uncharacterized protein. (285 aa)
	A0A158NNE4	Uncharacterized protein. (1312 aa)
	A0A158NNE7	Uncharacterized protein. (1043 aa)
	A0A158NNL7	WD_REPEATS_REGION domain-containing protein. (602 aa)
	A0A158NP91	Uncharacterized protein. (1810 aa)
	A0A158NQC2	Rho-GAP domain-containing protein. (632 aa)
	A0A158NQW0	Uncharacterized protein. (2434 aa)
	A0A158NR15	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1168 aa)
	A0A158NRQ5	Uncharacterized protein. (740 aa)
	A0A158NRT3	Uncharacterized protein. (192 aa)
	A0A158NRW3	Non-specific serine/threonine protein kinase. (672 aa)
	A0A158NRZ0	Uncharacterized protein. (1025 aa)
	A0A158NS81	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
	A0A158NSH9	Uncharacterized protein. (192 aa)
	A0A158NSI4	Uncharacterized protein. (244 aa)
	A0A158NSN3	Uncharacterized protein. (674 aa)
	A0A158NSR8	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1764 aa)
	A0A158NTI9	SH3 domain-containing protein. (664 aa)
	A0A158NTJ8	Uncharacterized protein. (191 aa)
	A0A158NTK8	Uncharacterized protein. (979 aa)
	A0A158NU55	Uncharacterized protein. (1084 aa)
	A0A158NUK2	BTB domain-containing protein. (622 aa)
	A0A158NV61	Uncharacterized protein. (694 aa)
	A0A158NVH7	Uncharacterized protein. (260 aa)
	A0A158NWB1	Uncharacterized protein. (1643 aa)
	A0A158NWC1	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (356 aa)
	A0A158NWF6	Non-specific serine/threonine protein kinase. (524 aa)
	A0A158NXB0	Uncharacterized protein. (169 aa)
	A0A158NXD4	Uncharacterized protein. (376 aa)
	A0A158NXF9	CRAL-TRIO domain-containing protein. (233 aa)
	A0A158NXU2	Uncharacterized protein. (376 aa)
	A0A158NY32	PH domain-containing protein. (1198 aa)
	A0A158NYA1	Uncharacterized protein. (252 aa)
	A0A158NYK4	FH2 domain-containing protein. (1296 aa)
	A0A158NYK5	Uncharacterized protein. (1179 aa)
	A0A158NYT1	Uncharacterized protein. (1238 aa)
	A0A158NYT8	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (160 aa)
	A0A158NZ36	Rho-GAP domain-containing protein. (262 aa)
	A0A158NZV1	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1371 aa)
	A0A158P094	Uncharacterized protein. (399 aa)
	A0A158P0Z8	Uncharacterized protein; Belongs to the actin family. (417 aa)
	A0A158P168	Transgelin; Belongs to the calponin family. (189 aa)
	A0A158P1D2	Uncharacterized protein. (421 aa)
	A0A158P3N0	Uncharacterized protein. (350 aa)
	A0A158P3R1	Uncharacterized protein. (2161 aa)
	A0A158P3W9	Uncharacterized protein. (195 aa)

Your Current Organism:

Atta cephalotes

NCBI taxonomy Id: 12957
Other names: A. cephalotes

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A158N932	A0A158NKH8	Uncharacterized protein.	WH2 domain-containing protein.	0.457
A0A158N932	A0A158NMV6	Uncharacterized protein.	Uncharacterized protein.	0.810
A0A158N932	A0A158NP91	Uncharacterized protein.	Uncharacterized protein.	0.852
A0A158N932	A0A158NTI9	Uncharacterized protein.	SH3 domain-containing protein.	0.509
A0A158N932	A0A158NTK8	Uncharacterized protein.	Uncharacterized protein.	0.586
A0A158N943	A0A158NDR9	Uncharacterized protein.	Transgelin; Belongs to the calponin family.	0.477
A0A158N943	A0A158NE73	Uncharacterized protein.	F-box domain-containing protein.	0.486
A0A158N943	A0A158NFW0	Uncharacterized protein.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.625
A0A158N943	A0A158NGD4	Uncharacterized protein.	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.611
A0A158N943	A0A158NGD5	Uncharacterized protein.	Uncharacterized protein.	0.477
A0A158N943	A0A158NGD6	Uncharacterized protein.	Uncharacterized protein.	0.477
A0A158N943	A0A158NHK5	Uncharacterized protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.711
A0A158N943	A0A158NI22	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.438
A0A158N943	A0A158NID7	Uncharacterized protein.	Urb2 domain-containing protein.	0.509
A0A158N943	A0A158NJD7	Uncharacterized protein.	Uncharacterized protein.	0.799
A0A158N943	A0A158NKH8	Uncharacterized protein.	WH2 domain-containing protein.	0.545
A0A158N943	A0A158NLU4	Uncharacterized protein.	HP domain-containing protein.	0.582
A0A158N943	A0A158NMV6	Uncharacterized protein.	Uncharacterized protein.	0.666
A0A158N943	A0A158NN34	Uncharacterized protein.	Uncharacterized protein.	0.486
A0A158N943	A0A158NNL7	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.554