(30 nodes) Regulation of actin dynamics for phagocytic cup formation, and ADF-H/Gelsolin-like domain superfamily network (Atta cephalotes)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	A0A158N943	Uncharacterized protein. (638 aa)
	A0A158NDB8	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (368 aa)
	A0A158NE73	F-box domain-containing protein. (338 aa)
	A0A158NEF1	WH2 domain-containing protein. (595 aa)
	A0A158NEL8	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1291 aa)
	A0A158NFW0	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (160 aa)
	A0A158NGD4	Adenylyl cyclase-associated protein; Belongs to the CAP family. (915 aa)
	A0A158NGD5	Uncharacterized protein. (169 aa)
	A0A158NGD6	Uncharacterized protein. (430 aa)
	A0A158NI22	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1010 aa)
	A0A158NID7	Urb2 domain-containing protein. (1223 aa)
	A0A158NIF2	Uncharacterized protein. (1546 aa)
	A0A158NIP0	SH3 domain-containing protein. (473 aa)
	A0A158NJD7	Uncharacterized protein. (471 aa)
	A0A158NLB8	Uncharacterized protein. (76 aa)
	A0A158NLU4	HP domain-containing protein. (814 aa)
	A0A158NMI2	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1142 aa)
	A0A158NMS9	Uncharacterized protein. (1122 aa)
	A0A158NNL7	WD_REPEATS_REGION domain-containing protein. (602 aa)
	A0A158NS81	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
	A0A158NTI9	SH3 domain-containing protein. (664 aa)
	A0A158NVH7	Uncharacterized protein. (260 aa)
	A0A158NWC1	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (356 aa)
	A0A158NXB0	Uncharacterized protein. (169 aa)
	A0A158NXU2	Uncharacterized protein. (376 aa)
	A0A158NYA1	Uncharacterized protein. (252 aa)
	A0A158NYT8	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (160 aa)
	A0A158P094	Uncharacterized protein. (399 aa)
	A0A158P0Z8	Uncharacterized protein; Belongs to the actin family. (417 aa)
	A0A158P3N0	Uncharacterized protein. (350 aa)

Your Current Organism:

Atta cephalotes

NCBI taxonomy Id: 12957
Other names: A. cephalotes

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A158N943	A0A158NE73	Uncharacterized protein.	F-box domain-containing protein.	0.486
A0A158N943	A0A158NFW0	Uncharacterized protein.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.625
A0A158N943	A0A158NGD4	Uncharacterized protein.	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.611
A0A158N943	A0A158NGD5	Uncharacterized protein.	Uncharacterized protein.	0.477
A0A158N943	A0A158NGD6	Uncharacterized protein.	Uncharacterized protein.	0.477
A0A158N943	A0A158NI22	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.438
A0A158N943	A0A158NID7	Uncharacterized protein.	Urb2 domain-containing protein.	0.509
A0A158N943	A0A158NJD7	Uncharacterized protein.	Uncharacterized protein.	0.799
A0A158N943	A0A158NLU4	Uncharacterized protein.	HP domain-containing protein.	0.582
A0A158N943	A0A158NNL7	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.554
A0A158N943	A0A158NWC1	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.758
A0A158N943	A0A158NXB0	Uncharacterized protein.	Uncharacterized protein.	0.616
A0A158N943	A0A158NXU2	Uncharacterized protein.	Uncharacterized protein.	0.616
A0A158N943	A0A158NYA1	Uncharacterized protein.	Uncharacterized protein.	0.616
A0A158N943	A0A158P094	Uncharacterized protein.	Uncharacterized protein.	0.486
A0A158N943	A0A158P0Z8	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.758
A0A158N943	A0A158P3N0	Uncharacterized protein.	Uncharacterized protein.	0.765
A0A158NDB8	A0A158NE73	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	F-box domain-containing protein.	0.607
A0A158NDB8	A0A158NEF1	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	WH2 domain-containing protein.	0.699
A0A158NDB8	A0A158NEL8	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	0.659