(56 nodes) Cytosolic transport network (Atta cephalotes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A158P459	VPS9 domain-containing protein. (1119 aa)
	A0A158NA94	Dopey_N domain-containing protein. (2496 aa)
	A0A158NAU7	Uncharacterized protein. (381 aa)
	A0A158NBI5	Uncharacterized protein. (673 aa)
	A0A158NC78	Uncharacterized protein. (381 aa)
	A0A158NCJ7	PH domain-containing protein. (188 aa)
	A0A158NCP9	RIC1 domain-containing protein. (1416 aa)
	A0A158NDQ4	Uncharacterized protein. (1889 aa)
	A0A158NDR7	Foie-gras_1 domain-containing protein. (1180 aa)
	A0A158NDS6	Sorting nexin; Involved in several stages of intracellular trafficking. (414 aa)
	A0A158NEM1	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (268 aa)
	A0A158NHT2	Uncharacterized protein. (253 aa)
	A0A158NHU4	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1245 aa)
	A0A158NI73	Uncharacterized protein. (524 aa)
	A0A158NIK9	Uncharacterized protein. (238 aa)
	A0A158NJ95	Uncharacterized protein. (967 aa)
	A0A158NJF6	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (836 aa)
	A0A158NK85	Uncharacterized protein. (665 aa)
	A0A158NK92	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (179 aa)
	A0A158NKL6	Uncharacterized protein. (514 aa)
	A0A158NKS3	CAP-ZIP_m domain-containing protein. (1643 aa)
	A0A158NKV8	Uncharacterized protein. (1319 aa)
	A0A158NLJ4	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (803 aa)
	A0A158NMH8	Uncharacterized protein. (211 aa)
	A0A158NMP5	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1309 aa)
	A0A158NMU0	Uncharacterized protein. (643 aa)
	A0A158NN99	Uncharacterized protein. (2089 aa)
	A0A158NNH4	Uncharacterized protein. (1311 aa)
	A0A158NP16	CTP_transf_like domain-containing protein. (523 aa)
	A0A158NPW7	Uncharacterized protein. (218 aa)
	A0A158NQ09	PX domain-containing protein. (248 aa)
	A0A158NQG2	PH domain-containing protein. (215 aa)
	A0A158NQJ0	Adaptin_N domain-containing protein. (1196 aa)
	A0A158NQW0	Uncharacterized protein. (2434 aa)
	A0A158NR86	Uncharacterized protein. (207 aa)
	A0A158NRR8	WH2 domain-containing protein. (493 aa)
	A0A158NSE5	Uncharacterized protein. (299 aa)
	A0A158NSJ6	Uncharacterized protein. (304 aa)
	A0A158NT23	Uncharacterized protein. (2486 aa)
	A0A158NU36	WH1 domain-containing protein. (420 aa)
	A0A158NUC2	Protein SYS1 homolog; Involved in protein trafficking. Belongs to the SYS1 family. (160 aa)
	A0A158NUC6	Uncharacterized protein. (398 aa)
	A0A158NUM9	Uncharacterized protein. (1527 aa)
	A0A158NUW6	PX domain-containing protein. (163 aa)
	A0A158NV20	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (213 aa)
	A0A158NW37	Uncharacterized protein. (114 aa)
	A0A158NXY7	Pep3_Vps18 domain-containing protein. (1003 aa)
	A0A158NYZ4	t-SNARE coiled-coil homology domain-containing protein. (289 aa)
	A0A158NZ28	t-SNARE coiled-coil homology domain-containing protein. (231 aa)
	A0A158P0X6	Uncharacterized protein. (140 aa)
	A0A158P1G8	Vps53_N domain-containing protein. (834 aa)
	A0A158P1S9	Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (203 aa)
	A0A158P283	PX domain-containing protein. (510 aa)
	A0A158P2E0	Uncharacterized protein. (971 aa)
	A0A158P2V1	Uncharacterized protein. (1953 aa)
	A0A158P347	Uncharacterized protein. (371 aa)

Your Current Organism:

Atta cephalotes

NCBI taxonomy Id: 12957
Other names: A. cephalotes

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A158NAU7	A0A158NDS6	Uncharacterized protein.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.721
A0A158NAU7	A0A158NIK9	Uncharacterized protein.	Uncharacterized protein.	0.660
A0A158NAU7	A0A158NJF6	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.439
A0A158NAU7	A0A158NKL6	Uncharacterized protein.	Uncharacterized protein.	0.707
A0A158NAU7	A0A158NKS3	Uncharacterized protein.	CAP-ZIP_m domain-containing protein.	0.570
A0A158NAU7	A0A158NLJ4	Uncharacterized protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.999
A0A158NAU7	A0A158NMH8	Uncharacterized protein.	Uncharacterized protein.	0.416
A0A158NAU7	A0A158NQ09	Uncharacterized protein.	PX domain-containing protein.	0.406
A0A158NAU7	A0A158NSE5	Uncharacterized protein.	Uncharacterized protein.	0.536
A0A158NAU7	A0A158NUW6	Uncharacterized protein.	PX domain-containing protein.	0.987
A0A158NAU7	A0A158NV20	Uncharacterized protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.999
A0A158NAU7	A0A158P283	Uncharacterized protein.	PX domain-containing protein.	0.984
A0A158NAU7	A0A158P2V1	Uncharacterized protein.	Uncharacterized protein.	0.408
A0A158NBI5	A0A158NUW6	Uncharacterized protein.	PX domain-containing protein.	0.408
A0A158NC78	A0A158NCP9	Uncharacterized protein.	RIC1 domain-containing protein.	0.967
A0A158NC78	A0A158NK85	Uncharacterized protein.	Uncharacterized protein.	0.713
A0A158NC78	A0A158NMH8	Uncharacterized protein.	Uncharacterized protein.	0.842
A0A158NC78	A0A158NUC6	Uncharacterized protein.	Uncharacterized protein.	0.647
A0A158NC78	A0A158NW37	Uncharacterized protein.	Uncharacterized protein.	0.462
A0A158NC78	A0A158NYZ4	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.532