(7 nodes) 5-flap endonuclease activity network (Atta cephalotes)

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Your Input:
	A0A158NIG0	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (268 aa)
	A0A158NK54	Uncharacterized protein. (1235 aa)
	A0A158NKL2	Uncharacterized protein. (722 aa)
	A0A158P3D6	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (902 aa)
	A0A158NYU3	Uncharacterized protein. (744 aa)
	Fen1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (381 aa)
	A0A158NSN9	Uncharacterized protein. (1114 aa)

Your Current Organism:

Atta cephalotes

NCBI taxonomy Id: 12957
Other names: A. cephalotes

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A158NIG0	A0A158NK54	A0A158NIG0	A0A158NK54	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	Uncharacterized protein.	0.781
A0A158NIG0	A0A158NKL2	A0A158NIG0	A0A158NKL2	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	Uncharacterized protein.	0.817
A0A158NIG0	A0A158NSN9	A0A158NIG0	A0A158NSN9	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	Uncharacterized protein.	0.737
A0A158NIG0	A0A158NYU3	A0A158NIG0	A0A158NYU3	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	Uncharacterized protein.	0.544
A0A158NIG0	A0A158P3D6	A0A158NIG0	A0A158P3D6	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.728
A0A158NIG0	Fen1	A0A158NIG0	A0A158NF76	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.697
A0A158NK54	A0A158NIG0	A0A158NK54	A0A158NIG0	Uncharacterized protein.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.781
A0A158NK54	A0A158NKL2	A0A158NK54	A0A158NKL2	Uncharacterized protein.	Uncharacterized protein.	0.952
A0A158NK54	A0A158NSN9	A0A158NK54	A0A158NSN9	Uncharacterized protein.	Uncharacterized protein.	0.822
A0A158NK54	A0A158NYU3	A0A158NK54	A0A158NYU3	Uncharacterized protein.	Uncharacterized protein.	0.848
A0A158NK54	Fen1	A0A158NK54	A0A158NF76	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.941
A0A158NKL2	A0A158NIG0	A0A158NKL2	A0A158NIG0	Uncharacterized protein.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.817
A0A158NKL2	A0A158NK54	A0A158NKL2	A0A158NK54	Uncharacterized protein.	Uncharacterized protein.	0.952
A0A158NKL2	A0A158NSN9	A0A158NKL2	A0A158NSN9	Uncharacterized protein.	Uncharacterized protein.	0.509
A0A158NKL2	A0A158NYU3	A0A158NKL2	A0A158NYU3	Uncharacterized protein.	Uncharacterized protein.	0.735
A0A158NKL2	Fen1	A0A158NKL2	A0A158NF76	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.851
A0A158NSN9	A0A158NIG0	A0A158NSN9	A0A158NIG0	Uncharacterized protein.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.737
A0A158NSN9	A0A158NK54	A0A158NSN9	A0A158NK54	Uncharacterized protein.	Uncharacterized protein.	0.822
A0A158NSN9	A0A158NKL2	A0A158NSN9	A0A158NKL2	Uncharacterized protein.	Uncharacterized protein.	0.509
A0A158NYU3	A0A158NIG0	A0A158NYU3	A0A158NIG0	Uncharacterized protein.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.544