(10 nodes) Mitotic DNA replication checkpoint signaling network (Atta cephalotes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A158NM71	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (561 aa)
	A0A158NF17	Uncharacterized protein. (1267 aa)
	A0A158NFI1	Checkpoint protein; Belongs to the HUS1 family. (275 aa)
	A0A158NHE7	Ig-like domain-containing protein. (163 aa)
	A0A158NKZ0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (471 aa)
	A0A158NLB5	Uncharacterized protein. (1200 aa)
	A0A158NS73	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2428 aa)
	A0A158NW28	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (415 aa)
	A0A158NY25	Uncharacterized protein. (436 aa)
	A0A158P3T8	Uncharacterized protein. (301 aa)

Your Current Organism:

Atta cephalotes

NCBI taxonomy Id: 12957
Other names: A. cephalotes

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A158NF17	A0A158NFI1	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.847
A0A158NF17	A0A158NHE7	Uncharacterized protein.	Ig-like domain-containing protein.	0.848
A0A158NF17	A0A158NKZ0	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.896
A0A158NF17	A0A158NLB5	Uncharacterized protein.	Uncharacterized protein.	0.882
A0A158NF17	A0A158NM71	Uncharacterized protein.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.716
A0A158NF17	A0A158NS73	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.974
A0A158NF17	A0A158NY25	Uncharacterized protein.	Uncharacterized protein.	0.875
A0A158NFI1	A0A158NF17	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.847
A0A158NFI1	A0A158NKZ0	Checkpoint protein; Belongs to the HUS1 family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.809
A0A158NFI1	A0A158NLB5	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.625
A0A158NFI1	A0A158NS73	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.880
A0A158NFI1	A0A158NY25	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.993
A0A158NHE7	A0A158NF17	Ig-like domain-containing protein.	Uncharacterized protein.	0.848
A0A158NHE7	A0A158NKZ0	Ig-like domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.480
A0A158NHE7	A0A158NLB5	Ig-like domain-containing protein.	Uncharacterized protein.	0.410
A0A158NHE7	A0A158NM71	Ig-like domain-containing protein.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.525
A0A158NKZ0	A0A158NF17	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.896
A0A158NKZ0	A0A158NFI1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Checkpoint protein; Belongs to the HUS1 family.	0.809
A0A158NKZ0	A0A158NHE7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Ig-like domain-containing protein.	0.480
A0A158NKZ0	A0A158NLB5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.980